FASUDIL - ≥98% (HPLC), high purity , Rho-associated protein kinase inhibitor, CAS No.103745-39-7, Rho-associated protein kinase inhibitor

Item Number

F134784

• Synonyms: KBio3_000841 | 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline | 5-((HEXAHYDRO-1H-1,4-DIAZEPIN-1-YL)SULFONYL)ISOQUINOLINE | cid_163751 | HMS1990G13 | Tocris-0541 | AB00490076-08 | BDBM14027 | 1-(5-Isoquinolinylsulfonyl)homopiperazine | ISOQUINOLI
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: ROCK2 inhibitor (IC 50 = 1.9 µM). Also shown to inhibit PRK2 (IC 50 = 4 µM), MSK1 (IC 50 = 5 µM), Rsk2 (IC 50 = 15 µM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Rho-associated protein kinase inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.