Febuxostat - ≥98%, high purity , Xanthine dehydrogenase inhibitor, CAS No.144060-53-7, Xanthine dehydrogenase inhibitor

Item Number

F125720

• Synonyms: Febuxostat | 144060-53-7 | Adenuric | Uloric | 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | Feburic | Tei 6720 | TMX 67 | TMX-67 | Tei-6720 | 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid | Zurig | C16H16N2O3S | Donifoxate | Febu
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.Highly potent, selective, non-competitive, non-purine xanthine oxidase inhibitor (K i = 0.6 nM). Inhibits xanthi
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Xanthine dehydrogenase inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

 Product Description：

Febuxostat(TEI 6720;TMX 67 ) is selective xanthine oxidase inhibitor with Ki of 0.6 nM.An inhibitor xanthine oxidase and xanthine dehydrogenase.

Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.