The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Febuxostat - ≥98%, high purity , Xanthine dehydrogenase inhibitor, CAS No.144060-53-7, Xanthine dehydrogenase inhibitor
Highly potent, selective, non-competitive, non-purine xanthine oxidase inhibitor
Basic Description Synonyms Febuxostat|144060-53-7|Adenuric|Uloric|2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid|Feburic|Tei 6720|TMX 67|TMX-67|Tei-6720|2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid|Zurig|C16H16N2O3S|Donifoxate|Febu Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Dry ice Grade Moligand™ Action Type INHIBITOR Mechanism of action Xanthine dehydrogenase inhibitor Product Description Product Description：
Febuxostat(TEI 6720;TMX 67 ) is selective xanthine oxidase inhibitor with Ki of 0.6 nM.An inhibitor xanthine oxidase and xanthine dehydrogenase.
Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.
Names and Identifiers IUPAC Name 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid INCHI InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20) InChi Key BQSJTQLCZDPROO-UHFFFAOYSA-N Canonical SMILES CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O Isomeric SMILES CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O Alternate CAS 144060-53-7 PubChem CID 134018 NSC Number 758874 MeSH Entry Terms 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid;6720, TEI;febuxostat;TEI 6720;TEI-6720;TEI6720;uloric Molecular Weight 316.38
Chemical and Physical Properties Solubility DMSO 63 mg/mL Water <1 mg/mL Ethanol <1 mg/mL Melt Point(°C) 209 °C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H413: May cause long lasting harmful effects to aquatic life
H302: Harmful if swallowed
Precautionary Statements P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
Merck Index 3948
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
I2214496