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Feniralstat - 99%, high purity , CAS No.2166320-76-7

  • ≥99%
Item Number
F646248
Grouped product items
SKUSizeAvailabilityPrice Qty
F646248-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$544.90
F646248-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$879.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsFeniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC 50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC 50 >40 μM).
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Feniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC 50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC 50 >40 μM).

Form:Solid

Associated Targets

PRSS1 Tclin Trypsin-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLG Tclin Plasminogen 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLK1 Tchem Kallikrein-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLKB1 Tclin Plasma kallikrein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

F2 Tclin Prothrombin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES COCC1=NN(C=C1C(=O)NCC2=NC=CC(=C2F)OC)CC3=CC=C(C=C3)CN4C=C(C=CC4=O)F
Isomeric SMILES COCC1=NN(C=C1C(=O)NCC2=NC=CC(=C2F)OC)CC3=CC=C(C=C3)CN4C=C(C=CC4=O)F
PubChem CID 139301832
Molecular Weight 509.50

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (196.27 mM; ultrasonic and warming and heat to 60°C)

Related Documents

Solution Calculators