Fenofibrate - ≥98%, high purity , Peroxisome proliferator-activated receptor alpha agonist, CAS No.49562-28-9, Peroxisome proliferator-activated receptor alpha agonist

Item Number

F129682

• Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester | Fenofibrate (Standard) | FENOFIBRATE [EP MONOGRAPH] | Fenofibratum | Prestwick_217 | CAS-49562-28-9 | Fenofibrate micronized | NCGC00015437-10 | Pharmavit | Propanoic acid, 2-(4-(
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Fenofibrate is a hypolipidemic compound which acts as a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 18 μM for mouse and EC50 = 30 μM for human). Fenofibrate also binds to PPARγ with at least 10-fold less affinity, and is inactive
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST, INHIBITOR
• Mechanism of action: Peroxisome proliferator-activated receptor alpha agonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

A hypolipidemic PPARα agonist.

Fenofibrate has been used:

• to study its effect on plasma lipids, liver phenotype and gene expression；

• to study its impact on endothelium-dependent vasodilatation of thoracic aorta；

• to administer to NASH knock-in mice along with a high fat diet (HFD) to study its effect