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Fenretinide - ≥98%, high purity , CAS No.65646-68-6

≥98%

CAS#: 65646-68-6
Formula: C₂₆H₃₃NO₂
Molecular Weight: 391.55
MDL number: MFCD00792674
PubChem CID: 5288209

Item Number

F126912

Grouped product items
SKU	Size	Availability	Price
F126912-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$64.90
F126912-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$90.90
F126912-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$115.90
F126912-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$155.90
F126912-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$351.90

Synthetic retinoid agonist

View related series

Pharmaceutical ingredients

Basic Description

Synonyms	FENRETINIDE\|65646-68-6\|N-(4-Hydroxyphenyl)retinamide\|4-HPR\|4-hydroxyphenylretinamide\|4-Hydroxyphenyl retinamide\|Retinoic acid p-hydroxyanilide\|all-trans-4'-Hydroxyretinanilide\|McN-R-1967\|Fenretinida\|Fenretinidum\|4-hydroxy(phenyl)retinamide\|N-(4-Hydroxyphe
Specifications & Purity	≥98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Dry ice
Product Description	Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death. An agonist displaying activity at retinoid receptors

Associated Targets

RBP4 Tchem Retinol-binding protein 4 1 Activities

Discover Target: RBP4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide
INCHI	InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChi Key	AKJHMTWEGVYYSE-FXILSDISSA-N
Canonical SMILES	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
Isomeric SMILES	CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)NC2=CC=C(C=C2)O)/C)/C
WGK Germany	3
RTECS	VH6420000
PubChem CID	5288209
Molecular Weight	391.55

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
A1911112	Certificate of Analysis	Jun 14, 2024	F126912
H1507111	Certificate of Analysis	Apr 13, 2023	F126912
A1911111	Certificate of Analysis	Sep 17, 2022	F126912

Chemical and Physical Properties

Solubility	Soluble in DMSO (25 mg/ml), ethanol (25 mg/ml)), chloroform, and acetone (easily soluble).
Sensitivity	Air & Heat sensitive
Melt Point(°C)	172 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H360:May damage fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	VH6420000
Merck Index	3998

References

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