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Ferrostatin-1 (Fer-1) - ≥99%, high purity , CAS No.347174-05-4

20 Citations

≥99%

CAS#: 347174-05-4
Formula: C₁₅H₂₂N₂O₂
Molecular Weight: 262.35
PubChem CID: 4068248

Item Number

F129882

Grouped product items
SKU	Size	Availability	Price
F129882-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
F129882-25mg	25mg	In stock	$23.90
F129882-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$79.90
F129882-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$299.90

Potent, selective erastin-induced ferroptosis inhibitor

View related series

Antifungal Ingredients (for Research and Experimental Use) Antioxidant and Free Radical Scavengers [Bioactive Small Molecules] Ferroptosis inhibitors

Basic Description

Synonyms	Ferrostatin-1 \| 347174-05-4 \| Ethyl 3-amino-4-(cyclohexylamino)benzoate \| Ferrostatin-1 (Fer-1) \| Ferrostatin 1 \| Fer-1 \| Benzoic acid, 3-amino-4-(cyclohexylamino)-, ethyl ester \| 3-amino-4-cyclohexylaminobenzoic acid ethyl ester \| MFCD08072959 \| 3-amino-4-(cyclohexylamino
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Ferrostatin-1 (2 μM) prevents erastin-induced ferroptosis in cancer cells, as well as glutamate-induced cell death in postnatal rat brain slices. Ferrostatin-1 is a lipid ROS scavenger, with the N-cyclohexyl moiety serving as a lipo-philic anchor within b
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. A potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity.

Associated Targets(Human)

HT-1080 (3966 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HT-29 (80576 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IMR-32 (1082 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

T-24 (2342 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Leishmania major (2877 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LLC-MK2 (227 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NIH3T3 (5395 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HT-22 (3261 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Liver microsome (341 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	ethyl 3-amino-4-(cyclohexylamino)benzoate
INCHI	InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3
InChi Key	UJHBVMHOBZBWMX-UHFFFAOYSA-N
Canonical SMILES	CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N
Isomeric SMILES	CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N
PubChem CID	4068248
Molecular Weight	262.35

Certificates

Certificate of Analysis(COA)

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26 results found

Lot Number	Certificate Type	Date	Item
H2405444	Certificate of Analysis	Jun 06, 2024	F129882
H2405445	Certificate of Analysis	Jun 06, 2024	F129882
H2405446	Certificate of Analysis	Jun 06, 2024	F129882
H2405447	Certificate of Analysis	Jun 06, 2024	F129882
F2406190	Certificate of Analysis	May 24, 2024	F129882
F2406191	Certificate of Analysis	May 24, 2024	F129882
F2406192	Certificate of Analysis	May 24, 2024	F129882
C2406139	Certificate of Analysis	Feb 06, 2024	F129882
C2406140	Certificate of Analysis	Feb 06, 2024	F129882
C2406141	Certificate of Analysis	Feb 06, 2024	F129882
C2406138	Certificate of Analysis	Feb 06, 2024	F129882
J2323608	Certificate of Analysis	Oct 11, 2023	F129882
J2323607	Certificate of Analysis	Oct 11, 2023	F129882
J2323606	Certificate of Analysis	Oct 11, 2023	F129882
I2206792	Certificate of Analysis	Sep 19, 2022	F129882
I2206793	Certificate of Analysis	Sep 19, 2022	F129882
I2206738	Certificate of Analysis	Sep 19, 2022	F129882
I2206794	Certificate of Analysis	Sep 17, 2022	F129882
I2308179	Certificate of Analysis	Aug 27, 2022	F129882
J2227331	Certificate of Analysis	Aug 27, 2022	F129882
J2227336	Certificate of Analysis	Aug 27, 2022	F129882
J2227339	Certificate of Analysis	Aug 27, 2022	F129882
J2227381	Certificate of Analysis	Aug 27, 2022	F129882
J2307033	Certificate of Analysis	Aug 27, 2022	F129882
G2320169	Certificate of Analysis	Aug 27, 2022	F129882
F2301028	Certificate of Analysis	Aug 27, 2022	F129882

Chemical and Physical Properties

Solubility	DMSO 52 mg/mL Water <1 mg/mL Ethanol 52 mg/mL
Sensitivity	light & Air & Heat sensitive
Melt Point(°C)	106 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

Alternative Products

Citations of This Product

1. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li. (2024) A potent GPX4 degrader to induce ferroptosis in HT1080 cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 265 (116110). [PMID:38194774]
2. Tianxiang Wang, Changmei Yang, Zhiqiang Li, Ting Li, Ran Zhang, Yujiao Zhao, Tianyi Cheng, Zhaoyun Zong, Yingying Ma, Dongyuan Zhang, Haiteng Deng. (2024) Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biology, 69 (103017). [PMID:38176315]
3. Yijing Yang, Ying Wang, Ying Deng, Jing Lu, Li Xiao, Jie Li, Yasha Zhou, Fujiao Nie, Xiangdong Chen, Jun Peng, Hanyu Tan, Yuhui Qin, Qinghua Peng. (2023) Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa. BIOMEDICINE & PHARMACOTHERAPY, 167 (6): (115547). [PMID:37741257]
4. Xi Wang, Wenjing Zhu, Miao Xing, Haiyan Zhu, Enqing Chen, Jie Zhou. (2023) Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis. CHEMICO-BIOLOGICAL INTERACTIONS, 384 (18): (110713). [PMID:37716422]
5. Suleixin Yang, Yi Wu, Wenzhao Zhong, Ruie Chen, Meilin Wang, Meiwan Chen. (2023) GSH/Ph Dual Activatable Crosslinked And Fluorinated Pei for Cancer Gene Therapy Through Endogenous Iron De-Hijacking And in Situ Ros Amplification. ADVANCED MATERIALS, (2304098). [PMID:37689975]
6. Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu. (2023) Neutrophil membrane biomimetic delivery system (Ptdser-NM-Lipo/Fer-1) designed for targeting atherosclerosis therapy. IET Nanobiotechnology, 17 (4): (387-395). [PMID:37183611]
7. Zhao Hongting, Zhang Meng, Zhang Jinghua, Sun Zichen, Zhang Wenxin, Dong Weichen, Cheng Chen, Yao Yongzhong, Li Kuanyu. (2023) Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth. Cell and Bioscience, 13 (1): (1-15). [PMID:37179385]
8. Yu-Chen Chen, Qiong Zheng, Hui Lu, Yi-Xin Zhuang, Ting-Ting Gong, Lie-Feng Ma, Zha-Jun Zhan. (2023) Neuroprotective flavonoids from Epimedium brevicornu by inhibition of ferroptosis. Phytochemistry Letters, 55 (80). [PMID:]
9. Xia Chen, Rong Wu, Lei Li, Yunong Zeng, Jingrui Chen, Mingyuan Wei, Yinglin Feng, Guiming Chen, Yuhang Wang, Lizhen Lin, Haihua Luo, Ali Chen, Zhenhua Zeng, Fangjie He, Yang Bai, Siyou Zhang, Yubing Han, Zhang Wang, Xiaoshan Zhao, Wei Xiao, Yong Jiang, Shenhai Gong. (2023) Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. IMMUNITY, 56 (336-352.e9). [PMID:36792573]
10. Wenhua Wang, Wenhao Wang, Shiwei Jin, Fangqin Fu, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan. (2023) Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. CHEMICAL ENGINEERING JOURNAL, 458 (141487). [PMID:]
11. Huiyi Li, Qiqing Weng, Shuai Gong, Weixian Zhang, Jiaqi Wang, Yuqiao Huang, Yuanjun Li, Jiao Guo, Tian Lan. (2023) Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation. Food & Function, 14 (4): (1884-1896). [PMID:36723004]
12. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233]
13. Huan Huang, Yuling Chen, Na Yin, Gaojie Li, Shanshan Ye, Ling Guo, Min Feng. (2023) Unsaturated Fatty Acid Liposomes Selectively Regulate Glutathione Peroxidase 4 to Exacerbate Lipid Peroxidation as an Adaptable Liposome Platform for Anti-Tumor Therapy. MOLECULAR PHARMACEUTICS, 20 (1): (290–302). [PMID:36368878]
14. Li Xie, Wenjie Chen, Qifang Chen, Yang Jiang, Erqun Song, Xiaokang Zhu, Yang Song. (2022) Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory. Materials Today Bio, 16 (100353). [PMID:35865409]
15. Shuwei Qiao, Baosheng Li, Qing Cai, Zhen Li, Zhaoyi Yin, Jie He, Yuyang Li, Weiyan Meng. (2022) Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo. ORAL DISEASES, [PMID:35765229]
16. Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma. (2022) Dual-Responsive multifunctional “core–shell” magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 622 (121898). [PMID:35688287]
17. Feng-guo Zhai, Qi-chao Liang, Yi-yan Wu, Jia-qi Liu, Jia-wei Liu. (2022) Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis. PHARMACEUTICAL BIOLOGY, 60 (1): (909-914). [PMID:35575436]
18. Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pan. (2022) Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS Nano, 16 (5): (8370–8387). [PMID:35575209]
19. Fengfan Liu, Xiang Cheng, Shuang Wu, Bei Hu, Chen Yang, Shufen Deng, Qiwen Shi. (2022) Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3. ENVIRONMENTAL TOXICOLOGY, 37 (5): (1093-1103). [PMID:35061333]
20. Haibao Peng, Xingcai Zhang, Peng Yang, Jiaxu Zhao, Wei Zhang, Nianping Feng, Wuli Yang, Jing Tang. (2023) Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance. Bioactive Materials, 19 (1). [PMID:35415315]

References

1. Henning Y et al.. (2022) Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.. Cell Death Dis, 13 (7): (662). [PMID:35906211]
2. Wenzel SE et al.. (2017) PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.. Cell, 171 (3): (628-641.e26). [PMID:29053969]
3. Xiaosi Lin , Le Dong, Qing Miao, Zhaobin Huang, Fang Wang. (2024) Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small cell lung cancer cell lines. European Journal of Pharmacology, 无 (974): (176608). [PMID:38663542]
4. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li. (2024) A potent GPX4 degrader to induce ferroptosis in HT1080 cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 265 (116110). [PMID:38194774]
5. Tianxiang Wang, Changmei Yang, Zhiqiang Li, Ting Li, Ran Zhang, Yujiao Zhao, Tianyi Cheng, Zhaoyun Zong, Yingying Ma, Dongyuan Zhang, Haiteng Deng. (2024) Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biology, 69 (103017). [PMID:38176315]
6. Yijing Yang, Ying Wang, Ying Deng, Jing Lu, Li Xiao, Jie Li, Yasha Zhou, Fujiao Nie, Xiangdong Chen, Jun Peng, Hanyu Tan, Yuhui Qin, Qinghua Peng. (2023) Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa. BIOMEDICINE & PHARMACOTHERAPY, 167 (6): (115547). [PMID:37741257]
7. Xi Wang, Wenjing Zhu, Miao Xing, Haiyan Zhu, Enqing Chen, Jie Zhou. (2023) Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis. CHEMICO-BIOLOGICAL INTERACTIONS, 384 (18): (110713). [PMID:37716422]
8. Suleixin Yang, Yi Wu, Wenzhao Zhong, Ruie Chen, Meilin Wang, Meiwan Chen. (2023) GSH/Ph Dual Activatable Crosslinked And Fluorinated Pei for Cancer Gene Therapy Through Endogenous Iron De-Hijacking And in Situ Ros Amplification. ADVANCED MATERIALS, (2304098). [PMID:37689975]
9. Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu. (2023) Neutrophil membrane biomimetic delivery system (Ptdser-NM-Lipo/Fer-1) designed for targeting atherosclerosis therapy. IET Nanobiotechnology, 17 (4): (387-395). [PMID:37183611]
10. Zhao Hongting, Zhang Meng, Zhang Jinghua, Sun Zichen, Zhang Wenxin, Dong Weichen, Cheng Chen, Yao Yongzhong, Li Kuanyu. (2023) Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth. Cell and Bioscience, 13 (1): (1-15). [PMID:37179385]
11. Yu-Chen Chen, Qiong Zheng, Hui Lu, Yi-Xin Zhuang, Ting-Ting Gong, Lie-Feng Ma, Zha-Jun Zhan. (2023) Neuroprotective flavonoids from Epimedium brevicornu by inhibition of ferroptosis. Phytochemistry Letters, 55 (80). [PMID:]
12. Xia Chen, Rong Wu, Lei Li, Yunong Zeng, Jingrui Chen, Mingyuan Wei, Yinglin Feng, Guiming Chen, Yuhang Wang, Lizhen Lin, Haihua Luo, Ali Chen, Zhenhua Zeng, Fangjie He, Yang Bai, Siyou Zhang, Yubing Han, Zhang Wang, Xiaoshan Zhao, Wei Xiao, Yong Jiang, Shenhai Gong. (2023) Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. IMMUNITY, 56 (336-352.e9). [PMID:36792573]
13. Wenhua Wang, Wenhao Wang, Shiwei Jin, Fangqin Fu, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan. (2023) Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. CHEMICAL ENGINEERING JOURNAL, 458 (141487). [PMID:]
14. Huiyi Li, Qiqing Weng, Shuai Gong, Weixian Zhang, Jiaqi Wang, Yuqiao Huang, Yuanjun Li, Jiao Guo, Tian Lan. (2023) Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation. Food & Function, 14 (4): (1884-1896). [PMID:36723004]
15. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233]
16. Huan Huang, Yuling Chen, Na Yin, Gaojie Li, Shanshan Ye, Ling Guo, Min Feng. (2023) Unsaturated Fatty Acid Liposomes Selectively Regulate Glutathione Peroxidase 4 to Exacerbate Lipid Peroxidation as an Adaptable Liposome Platform for Anti-Tumor Therapy. MOLECULAR PHARMACEUTICS, 20 (1): (290–302). [PMID:36368878]
17. Li Xie, Wenjie Chen, Qifang Chen, Yang Jiang, Erqun Song, Xiaokang Zhu, Yang Song. (2022) Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory. Materials Today Bio, 16 (100353). [PMID:35865409]
18. Shuwei Qiao, Baosheng Li, Qing Cai, Zhen Li, Zhaoyi Yin, Jie He, Yuyang Li, Weiyan Meng. (2022) Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo. ORAL DISEASES, [PMID:35765229]
19. Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma. (2022) Dual-Responsive multifunctional “core–shell” magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 622 (121898). [PMID:35688287]
20. Feng-guo Zhai, Qi-chao Liang, Yi-yan Wu, Jia-qi Liu, Jia-wei Liu. (2022) Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis. PHARMACEUTICAL BIOLOGY, 60 (1): (909-914). [PMID:35575436]
21. Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pan. (2022) Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS Nano, 16 (5): (8370–8387). [PMID:35575209]
22. Fengfan Liu, Xiang Cheng, Shuang Wu, Bei Hu, Chen Yang, Shufen Deng, Qiwen Shi. (2022) Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3. ENVIRONMENTAL TOXICOLOGY, 37 (5): (1093-1103). [PMID:35061333]
23. Haibao Peng, Xingcai Zhang, Peng Yang, Jiaxu Zhao, Wei Zhang, Nianping Feng, Wuli Yang, Jing Tang. (2023) Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance. Bioactive Materials, 19 (1). [PMID:35415315]

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