Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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F129882-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $9.90 | |
F129882-25mg | 25mg | In stock | $23.90 | |
F129882-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $79.90 | |
F129882-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $299.90 |
Potent, selective erastin-induced ferroptosis inhibitor
Synonyms | Ethyl 3-amino-4-(cyclohexylamino)benzoate | 3-Amino-4-cyclohexylaminobenzoic Acid Ethyl Ester |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Ferrostatin-1 (2 μM) prevents erastin-induced ferroptosis in cancer cells, as well as glutamate-induced cell death in postnatal rat brain slices. Ferrostatin-1 is a lipid ROS scavenger, with the N-cyclohexyl moiety serving as a lipo-philic anchor within b |
Storage Temp | Store at 2-8°C,Protected from light,Argon charged |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity.
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | ethyl 3-amino-4-(cyclohexylamino)benzoate |
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INCHI | InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3 |
InChi Key | UJHBVMHOBZBWMX-UHFFFAOYSA-N |
Canonical SMILES | CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N |
Isomeric SMILES | CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N |
PubChem CID | 4068248 |
Molecular Weight | 262.35 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2412627 | Certificate of Analysis | Nov 30, 2024 | F129882 |
L2412622 | Certificate of Analysis | Nov 30, 2024 | F129882 |
L2412621 | Certificate of Analysis | Nov 30, 2024 | F129882 |
L2412567 | Certificate of Analysis | Nov 30, 2024 | F129882 |
H2405447 | Certificate of Analysis | Jun 06, 2024 | F129882 |
H2405444 | Certificate of Analysis | Jun 06, 2024 | F129882 |
H2405445 | Certificate of Analysis | Jun 06, 2024 | F129882 |
H2405446 | Certificate of Analysis | Jun 06, 2024 | F129882 |
F2406190 | Certificate of Analysis | May 24, 2024 | F129882 |
F2406191 | Certificate of Analysis | May 24, 2024 | F129882 |
F2406192 | Certificate of Analysis | May 24, 2024 | F129882 |
C2406139 | Certificate of Analysis | Feb 06, 2024 | F129882 |
C2406138 | Certificate of Analysis | Feb 06, 2024 | F129882 |
C2406140 | Certificate of Analysis | Feb 06, 2024 | F129882 |
C2406141 | Certificate of Analysis | Feb 06, 2024 | F129882 |
J2323608 | Certificate of Analysis | Oct 11, 2023 | F129882 |
J2323607 | Certificate of Analysis | Oct 11, 2023 | F129882 |
J2323606 | Certificate of Analysis | Oct 11, 2023 | F129882 |
I2206738 | Certificate of Analysis | Sep 19, 2022 | F129882 |
I2206793 | Certificate of Analysis | Sep 19, 2022 | F129882 |
I2206792 | Certificate of Analysis | Sep 19, 2022 | F129882 |
I2206794 | Certificate of Analysis | Sep 17, 2022 | F129882 |
J2227336 | Certificate of Analysis | Aug 27, 2022 | F129882 |
J2227339 | Certificate of Analysis | Aug 27, 2022 | F129882 |
J2227381 | Certificate of Analysis | Aug 27, 2022 | F129882 |
J2307033 | Certificate of Analysis | Aug 27, 2022 | F129882 |
J2227331 | Certificate of Analysis | Aug 27, 2022 | F129882 |
I2308179 | Certificate of Analysis | Aug 27, 2022 | F129882 |
F2301028 | Certificate of Analysis | Aug 27, 2022 | F129882 |
G2320169 | Certificate of Analysis | Aug 27, 2022 | F129882 |
Solubility | DMSO 52 mg/mL Water <1 mg/mL Ethanol 52 mg/mL |
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Sensitivity | light & Air & Heat sensitive |
Melt Point(°C) | 106 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
Starting at $59.90
1. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li. (2024) A potent GPX4 degrader to induce ferroptosis in HT1080 cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 265 (116110). [PMID:38194774] |
2. Tianxiang Wang, Changmei Yang, Zhiqiang Li, Ting Li, Ran Zhang, Yujiao Zhao, Tianyi Cheng, Zhaoyun Zong, Yingying Ma, Dongyuan Zhang, Haiteng Deng. (2024) Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biology, 69 (103017). [PMID:38176315] |
3. Yijing Yang, Ying Wang, Ying Deng, Jing Lu, Li Xiao, Jie Li, Yasha Zhou, Fujiao Nie, Xiangdong Chen, Jun Peng, Hanyu Tan, Yuhui Qin, Qinghua Peng. (2023) Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa. BIOMEDICINE & PHARMACOTHERAPY, 167 (6): (115547). [PMID:37741257] |
4. Xi Wang, Wenjing Zhu, Miao Xing, Haiyan Zhu, Enqing Chen, Jie Zhou. (2023) Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis. CHEMICO-BIOLOGICAL INTERACTIONS, 384 (18): (110713). [PMID:37716422] |
5. Suleixin Yang, Yi Wu, Wenzhao Zhong, Ruie Chen, Meilin Wang, Meiwan Chen. (2023) GSH/Ph Dual Activatable Crosslinked And Fluorinated Pei for Cancer Gene Therapy Through Endogenous Iron De-Hijacking And in Situ Ros Amplification. ADVANCED MATERIALS, (2304098). [PMID:37689975] |
6. Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu. (2023) Neutrophil membrane biomimetic delivery system (Ptdser-NM-Lipo/Fer-1) designed for targeting atherosclerosis therapy. IET Nanobiotechnology, 17 (4): (387-395). [PMID:37183611] |
7. Zhao Hongting, Zhang Meng, Zhang Jinghua, Sun Zichen, Zhang Wenxin, Dong Weichen, Cheng Chen, Yao Yongzhong, Li Kuanyu. (2023) Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth. Cell and Bioscience, 13 (1): (1-15). [PMID:37179385] |
8. Yu-Chen Chen, Qiong Zheng, Hui Lu, Yi-Xin Zhuang, Ting-Ting Gong, Lie-Feng Ma, Zha-Jun Zhan. (2023) Neuroprotective flavonoids from Epimedium brevicornu by inhibition of ferroptosis. Phytochemistry Letters, 55 (80). [PMID:] |
9. Xia Chen, Rong Wu, Lei Li, Yunong Zeng, Jingrui Chen, Mingyuan Wei, Yinglin Feng, Guiming Chen, Yuhang Wang, Lizhen Lin, Haihua Luo, Ali Chen, Zhenhua Zeng, Fangjie He, Yang Bai, Siyou Zhang, Yubing Han, Zhang Wang, Xiaoshan Zhao, Wei Xiao, Yong Jiang, Shenhai Gong. (2023) Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. IMMUNITY, 56 (336-352.e9). [PMID:36792573] |
10. Wenhua Wang, Wenhao Wang, Shiwei Jin, Fangqin Fu, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan. (2023) Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. CHEMICAL ENGINEERING JOURNAL, 458 (141487). [PMID:] |
11. Huiyi Li, Qiqing Weng, Shuai Gong, Weixian Zhang, Jiaqi Wang, Yuqiao Huang, Yuanjun Li, Jiao Guo, Tian Lan. (2023) Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation. Food & Function, 14 (4): (1884-1896). [PMID:36723004] |
12. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233] |
13. Huan Huang, Yuling Chen, Na Yin, Gaojie Li, Shanshan Ye, Ling Guo, Min Feng. (2023) Unsaturated Fatty Acid Liposomes Selectively Regulate Glutathione Peroxidase 4 to Exacerbate Lipid Peroxidation as an Adaptable Liposome Platform for Anti-Tumor Therapy. MOLECULAR PHARMACEUTICS, 20 (1): (290–302). [PMID:36368878] |
14. Li Xie, Wenjie Chen, Qifang Chen, Yang Jiang, Erqun Song, Xiaokang Zhu, Yang Song. (2022) Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory. Materials Today Bio, 16 (100353). [PMID:35865409] |
15. Shuwei Qiao, Baosheng Li, Qing Cai, Zhen Li, Zhaoyi Yin, Jie He, Yuyang Li, Weiyan Meng. (2022) Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo. ORAL DISEASES, [PMID:35765229] |
16. Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma. (2022) Dual-Responsive multifunctional “core–shell” magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 622 (121898). [PMID:35688287] |
17. Feng-guo Zhai, Qi-chao Liang, Yi-yan Wu, Jia-qi Liu, Jia-wei Liu. (2022) Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis. PHARMACEUTICAL BIOLOGY, 60 (1): (909-914). [PMID:35575436] |
18. Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pan. (2022) Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS Nano, 16 (5): (8370–8387). [PMID:35575209] |
19. Fengfan Liu, Xiang Cheng, Shuang Wu, Bei Hu, Chen Yang, Shufen Deng, Qiwen Shi. (2022) Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3. ENVIRONMENTAL TOXICOLOGY, 37 (5): (1093-1103). [PMID:35061333] |
20. Haibao Peng, Xingcai Zhang, Peng Yang, Jiaxu Zhao, Wei Zhang, Nianping Feng, Wuli Yang, Jing Tang. (2023) Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance. Bioactive Materials, 19 (1). [PMID:35415315] |
21. Zhiwei Wang, Mingxing Li, Yuanfeng Liu, Zhentao Qiao, Tao Bai, Ling Yang, Bo Liu. (2021) Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression. ONCOLOGY REPORTS, 46 (5): (1-14). [PMID:34558645] |
22. Rong Fan, Jidong Sui, Xuepeng Dong, Biao Jing, Zhenming Gao. (2021) Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis. FREE RADICAL BIOLOGY AND MEDICINE, 173 (29). [PMID:34246777] |
23. Xiazhen Bao, Xuehui Cao, Yong Yuan, Bo Zhou, Congde Huo. (2021) A water-soluble, highly sensitive and ultrafast fluorescence probe for imaging of mitochondrial hypochlorous acid. SENSORS AND ACTUATORS B-CHEMICAL, 344 (130210). [PMID:] |
24. Wenjun Liu, Jieyuan Zhang, Liang Ding, Weifeng Ni, Junjie Yuan, Haijun Xiao, Jingwei Zhang. (2021) RBC-derived nanosystem with enhanced ferroptosis triggered by oxygen-boosted phototherapy for synergized tumor treatment. Biomaterials Science, 9 (21): (7228-7236). [PMID:34585181] |
25. Tao Bai, Ruopeng Liang, Rongtao Zhu, Weijie Wang, Lin Zhou, Yuling Sun. (2020) MicroRNA-214-3p enhances erastin-induced ferroptosis by targeting ATF4 in hepatoma cells. JOURNAL OF CELLULAR PHYSIOLOGY, 235 (7-8): (5637-5648). [PMID:31960438] |
1. Henning Y et al.. (2022) Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.. Cell Death Dis, 13 (7): (662). [PMID:35906211] |
2. Wenzel SE et al.. (2017) PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.. Cell, 171 (3): (628-641.e26). [PMID:29053969] |
3. Xiaosi Lin , Le Dong, Qing Miao, Zhaobin Huang, Fang Wang. (2024) Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small cell lung cancer cell lines. European Journal of Pharmacology, 无 (974): (176608). [PMID:38663542] |
4. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li. (2024) A potent GPX4 degrader to induce ferroptosis in HT1080 cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 265 (116110). [PMID:38194774] |
5. Tianxiang Wang, Changmei Yang, Zhiqiang Li, Ting Li, Ran Zhang, Yujiao Zhao, Tianyi Cheng, Zhaoyun Zong, Yingying Ma, Dongyuan Zhang, Haiteng Deng. (2024) Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biology, 69 (103017). [PMID:38176315] |
6. Yijing Yang, Ying Wang, Ying Deng, Jing Lu, Li Xiao, Jie Li, Yasha Zhou, Fujiao Nie, Xiangdong Chen, Jun Peng, Hanyu Tan, Yuhui Qin, Qinghua Peng. (2023) Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa. BIOMEDICINE & PHARMACOTHERAPY, 167 (6): (115547). [PMID:37741257] |
7. Xi Wang, Wenjing Zhu, Miao Xing, Haiyan Zhu, Enqing Chen, Jie Zhou. (2023) Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis. CHEMICO-BIOLOGICAL INTERACTIONS, 384 (18): (110713). [PMID:37716422] |
8. Suleixin Yang, Yi Wu, Wenzhao Zhong, Ruie Chen, Meilin Wang, Meiwan Chen. (2023) GSH/Ph Dual Activatable Crosslinked And Fluorinated Pei for Cancer Gene Therapy Through Endogenous Iron De-Hijacking And in Situ Ros Amplification. ADVANCED MATERIALS, (2304098). [PMID:37689975] |
9. Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu. (2023) Neutrophil membrane biomimetic delivery system (Ptdser-NM-Lipo/Fer-1) designed for targeting atherosclerosis therapy. IET Nanobiotechnology, 17 (4): (387-395). [PMID:37183611] |
10. Zhao Hongting, Zhang Meng, Zhang Jinghua, Sun Zichen, Zhang Wenxin, Dong Weichen, Cheng Chen, Yao Yongzhong, Li Kuanyu. (2023) Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth. Cell and Bioscience, 13 (1): (1-15). [PMID:37179385] |
11. Yu-Chen Chen, Qiong Zheng, Hui Lu, Yi-Xin Zhuang, Ting-Ting Gong, Lie-Feng Ma, Zha-Jun Zhan. (2023) Neuroprotective flavonoids from Epimedium brevicornu by inhibition of ferroptosis. Phytochemistry Letters, 55 (80). [PMID:] |
12. Xia Chen, Rong Wu, Lei Li, Yunong Zeng, Jingrui Chen, Mingyuan Wei, Yinglin Feng, Guiming Chen, Yuhang Wang, Lizhen Lin, Haihua Luo, Ali Chen, Zhenhua Zeng, Fangjie He, Yang Bai, Siyou Zhang, Yubing Han, Zhang Wang, Xiaoshan Zhao, Wei Xiao, Yong Jiang, Shenhai Gong. (2023) Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. IMMUNITY, 56 (336-352.e9). [PMID:36792573] |
13. Wenhua Wang, Wenhao Wang, Shiwei Jin, Fangqin Fu, Zhengwei Huang, Ying Huang, Chuanbin Wu, Xin Pan. (2023) Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. CHEMICAL ENGINEERING JOURNAL, 458 (141487). [PMID:] |
14. Huiyi Li, Qiqing Weng, Shuai Gong, Weixian Zhang, Jiaqi Wang, Yuqiao Huang, Yuanjun Li, Jiao Guo, Tian Lan. (2023) Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation. Food & Function, 14 (4): (1884-1896). [PMID:36723004] |
15. Mingbo Wu, Wenwu Ling, Jiaojun Wei, Ran Liao, Haiyue Sun, Dongqiu Li, Ye Zhao, Long Zhao. (2022) Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment. JOURNAL OF CONTROLLED RELEASE, 352 (1116). [PMID:36402233] |
16. Huan Huang, Yuling Chen, Na Yin, Gaojie Li, Shanshan Ye, Ling Guo, Min Feng. (2023) Unsaturated Fatty Acid Liposomes Selectively Regulate Glutathione Peroxidase 4 to Exacerbate Lipid Peroxidation as an Adaptable Liposome Platform for Anti-Tumor Therapy. MOLECULAR PHARMACEUTICS, 20 (1): (290–302). [PMID:36368878] |
17. Li Xie, Wenjie Chen, Qifang Chen, Yang Jiang, Erqun Song, Xiaokang Zhu, Yang Song. (2022) Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory. Materials Today Bio, 16 (100353). [PMID:35865409] |
18. Shuwei Qiao, Baosheng Li, Qing Cai, Zhen Li, Zhaoyi Yin, Jie He, Yuyang Li, Weiyan Meng. (2022) Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo. ORAL DISEASES, [PMID:35765229] |
19. Hao Chi, Guang Zhu, Yalin Yin, He Diao, Zicheng Liu, Shibo Sun, Zhaoming Guo, Weiping Xu, Jianqiang Xu, Changhao Cui, Xiao-Jin Xing, Kun Ma. (2022) Dual-Responsive multifunctional “core–shell” magnetic nanoparticles promoting Fenton reaction for tumor ferroptosis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 622 (121898). [PMID:35688287] |
20. Feng-guo Zhai, Qi-chao Liang, Yi-yan Wu, Jia-qi Liu, Jia-wei Liu. (2022) Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis. PHARMACEUTICAL BIOLOGY, 60 (1): (909-914). [PMID:35575436] |
21. Wenhao Wang, Fangqin Fu, Zhengwei Huang, Wenhua Wang, Minglong Chen, Xiao Yue, Jintao Fu, Xiaoqian Feng, Ying Huang, Chuanbin Wu, Xin Pan. (2022) Inhalable Biomimetic Protein Corona-Mediated Nanoreactor for Self-Amplified Lung Adenocarcinoma Ferroptosis Therapy. ACS Nano, 16 (5): (8370–8387). [PMID:35575209] |
22. Fengfan Liu, Xiang Cheng, Shuang Wu, Bei Hu, Chen Yang, Shufen Deng, Qiwen Shi. (2022) Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3. ENVIRONMENTAL TOXICOLOGY, 37 (5): (1093-1103). [PMID:35061333] |
23. Haibao Peng, Xingcai Zhang, Peng Yang, Jiaxu Zhao, Wei Zhang, Nianping Feng, Wuli Yang, Jing Tang. (2023) Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance. Bioactive Materials, 19 (1). [PMID:35415315] |
24. Zhiwei Wang, Mingxing Li, Yuanfeng Liu, Zhentao Qiao, Tao Bai, Ling Yang, Bo Liu. (2021) Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response‑induced upregulation of CHAC1 expression. ONCOLOGY REPORTS, 46 (5): (1-14). [PMID:34558645] |
25. Rong Fan, Jidong Sui, Xuepeng Dong, Biao Jing, Zhenming Gao. (2021) Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis. FREE RADICAL BIOLOGY AND MEDICINE, 173 (29). [PMID:34246777] |
26. Xiazhen Bao, Xuehui Cao, Yong Yuan, Bo Zhou, Congde Huo. (2021) A water-soluble, highly sensitive and ultrafast fluorescence probe for imaging of mitochondrial hypochlorous acid. SENSORS AND ACTUATORS B-CHEMICAL, 344 (130210). [PMID:] |
27. Wenjun Liu, Jieyuan Zhang, Liang Ding, Weifeng Ni, Junjie Yuan, Haijun Xiao, Jingwei Zhang. (2021) RBC-derived nanosystem with enhanced ferroptosis triggered by oxygen-boosted phototherapy for synergized tumor treatment. Biomaterials Science, 9 (21): (7228-7236). [PMID:34585181] |
28. Tao Bai, Ruopeng Liang, Rongtao Zhu, Weijie Wang, Lin Zhou, Yuling Sun. (2020) MicroRNA-214-3p enhances erastin-induced ferroptosis by targeting ATF4 in hepatoma cells. JOURNAL OF CELLULAR PHYSIOLOGY, 235 (7-8): (5637-5648). [PMID:31960438] |