Fertirelin - 99%, high purity , CAS No.38234-21-8

  • ≥99%
Item Number
F650250
Grouped product items
SKUSizeAvailabilityPrice Qty
F650250-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$72.90
F650250-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$120.90
F650250-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$168.90
F650250-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$228.90
View related series
GnRH Receptor GPCR/G Protein

Basic Description

SynonymsFertirelin | 38234-21-8 | Fertirelin acetate | DTXSID8057728 | 1-9-Luteinizing hormone-releasing factor (swine),9-(N-ethyl-L-prolinamide)- | Fertirelina | Fertireline | Fertirelinum | Fertireline [INN-French] | Fertirelin [INN:BAN] | Fertirelinum [INN-Latin] | Fertirelina [INN
Specifications & Purity≥99%
Biochemical and Physiological MechanismsFertirelin is a GnRH and LH-RH analogue; it also becomes the treatment choice for reversing cow follicular cysts.
Storage TempDesiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Fertirelin is a GnRH and LH-RH analogue; it also becomes the treatment choice for reversing cow follicular cysts.

In Vivo

Fertirelin, an analog of GnRH 2.5 to 10 times more potent than native GnRH , has become the treatment of choice for reversing follicular cysts . Administration of high doses of Fertirelin is found to reduce superovulatory responses. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal administration

Mice iparious female mice weighed 25-28 g (8-9 weeks) are used throughout the study. The mice are ddY strain and specific pathohen-free. As ovulation can be induced in mice at any time with administration of human chorionic gonadotrophin (hCG), 5.0 IU of hCG is injected subcutaneously into each mouse at 17:00, irrespective of the stage of the estrus cycle. This day is designated as Day 0. Nine groups are established according to the dose of Fertirelin ranging from 0.001 to 1.0 μg , and the administration are carried out at 22:00 on Day 0 and at 2:00, 6:00, 10:00 and 14:00 on Day 1 . aladdin has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Associated Targets(Human)

LHCGR Tclin Lutropin-choriogonadotropic hormone receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GNRHR Tclin Gonadotropin-releasing hormone receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LHCGR Tclin Luteinizing hormone/Choriogonadotropin receptor (373 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNRHR Tclin Gonadotropin-releasing hormone receptor (3398 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
INCHI InChI=1S/C55H76N16O12/c1-4-59-53(82)44-12-8-20-71(44)54(83)38(11-7-19-60-55(56)57)66-49(78)39(21-30(2)3)65-46(75)27-62-47(76)40(22-31-13-15-34(73)16-14-31)67-52(81)43(28-72)70-50(79)41(23-32-25-61-36-10-6-5-9-35(32)36)68-51(80)42(24-33-26-58-29-63-33)69-48(77)37-17-18-45(74)64-37/h5-6,9-10,13-16,25-26,29-30,37-44,61,72-73H,4,7-8,11-12,17-24,27-28H2,1-3H3,(H,58,63)(H,59,82)(H,62,76)(H,64,74)(H,65,75)(H,66,78)(H,67,81)(H,68,80)(H,69,77)(H,70,79)(H4,56,57,60)/t37-,38-,39-,40-,41-,42-,43-,44-/m0/s1
InChi Key DGCPIBPDYFLAAX-YTAGXALCSA-N
Canonical SMILES CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
Isomeric SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
Alternate CAS 38234-21-8,66002-66-2 (acetate)
PubChem CID 188304
MeSH Entry Terms 9-(N)-Et-ProNH2-10-des-GlyNH2-LHRH;9-N-Et-ProNH2-LHRH;desGly(10)-Pro(9)-LHRH ethylamide;DGNH-LHRH;fertilerine;fertilerine acetate;fertirelin;fertirelin acetate;GnRH, (N)-Et-ProNH2(9)-;GnRH, N-Et-ProNH2(9)-;LHRH, (N)-Et-ProNH2(9)-;LHRH, (N)-ethylprolinamid
Molecular Weight 1153.29

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : ≥ 100 mg/mL (86.71 mM) H2O : 100 mg/mL (86.71 mM; Need ultrasonic)

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Solution Calculators