Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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F156753-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 | |
F156753-1g | 1g | In stock | $145.90 | |
F156753-5g | 5g | In stock | $654.90 |
Selective type II 5α-reductase inhibitor
Synonyms | finasteride | 98319-26-7 | Proscar | Propecia | Finastid | Prostide | Chibro-Proscar | MK-906 | Finpecia | Finasterida | Finasteridum | Finasteridum [INN-Latin] | MK 906 | Finasterida [INN-Spanish] | CCRIS 7438 | MK 0906 | MK-0906 | HSDB 6793 | N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene- |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Finasteride is a synthetic 4-azasteroid antiandrogen compound. This specifically inhibits 5α-Reductase 2, an intracellular enzyme that converts the androgen testosterone into 5α dihydrotestosterone (DHT). Finasteride inhibits 5α-reductase activity in epit |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Steroid 5-alpha-reductase 2 inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM). |
ALogP | 3 |
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IUPAC Name | (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide |
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INCHI | InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1 |
InChi Key | DBEPLOCGEIEOCV-WSBQPABSSA-N |
Canonical SMILES | CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C |
Isomeric SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C |
WGK Germany | 3 |
RTECS | CL5245000 |
PubChem CID | 57363 |
Molecular Weight | 372.55 |
Reaxy-Rn | 4269024 |
DrugBank Ligand | DB01216 |
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PubChem CID | 57363 |
CAS Registry No. | 98319-26-7 |
ChEMBL Ligand | CHEMBL710 |
Wikipedia | Finasteride |
ChEBI | CHEBI:5062 |
RCSB PDB Ligand | FIT |
PEP | finasteride |
DrugCentral Ligand | 1171 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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J1810114 | Certificate of Analysis | Aug 10, 2022 | F156753 |
J1810113 | Certificate of Analysis | Aug 10, 2022 | F156753 |
I2209494 | Certificate of Analysis | Jul 16, 2022 | F156753 |
I2209495 | Certificate of Analysis | Jul 16, 2022 | F156753 |
Solubility | Soluble in DMSO, ethanol, methanol, and chloroform. |
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Melt Point(°C) | 253°C |
Pictogram(s) | GHS08, GHS09, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H410:Very toxic to aquatic life with long lasting effects H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child |
Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | CL5245000 |
Reaxy-Rn | 4269024 |
Merck Index | 4082 |
1. Yao Wang, Lili Liu, Cheng Cheng, Shuxuan Wang, Qirui Zhai, Yunyang Song, Ronghua Dai. (2023) Study on mechanism of Zishen Pill treating benign prostatic hyperplasia based on serum pharmacochemistry and network pharmacology. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115480). [PMID:37454501] |
2. Chi-Ming Liu, ZiChen Shao, XuZhou Chen, HanWu Chen, MengQiao Su, ZiWen Zhang, ZhengPing Wu, Peng Zhang, LiJie An, YinJie Jiang, Ai-Jun Ouyang. (2023) Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGF-β/Smad signaling pathways. SAUDI PHARMACEUTICAL JOURNAL, 31 (1219). [PMID:37293563] |
1. Yao Wang, Lili Liu, Cheng Cheng, Shuxuan Wang, Qirui Zhai, Yunyang Song, Ronghua Dai. (2023) Study on mechanism of Zishen Pill treating benign prostatic hyperplasia based on serum pharmacochemistry and network pharmacology. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115480). [PMID:37454501] |
2. Chi-Ming Liu, ZiChen Shao, XuZhou Chen, HanWu Chen, MengQiao Su, ZiWen Zhang, ZhengPing Wu, Peng Zhang, LiJie An, YinJie Jiang, Ai-Jun Ouyang. (2023) Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGF-β/Smad signaling pathways. SAUDI PHARMACEUTICAL JOURNAL, 31 (1219). [PMID:37293563] |