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FK-453 , Adenosine A1 receptor antagonist, CAS No.121524-18-3, Adenosine A1 receptor antagonist
Basic Description
| Synonyms | FK-453 | 121524-18-3 | FK 453 | (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one | (+)-(R)-((E)-3-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)acryloyl)-2-piperidineethanol | CHEMBL440115 | FK453 | FR-113453 | FR113452 | FR113453 |
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| Specifications & Purity | Moligand™ |
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| Grade | Moligand™ |
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| Action Type | ANTAGONIST |
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| Mechanism of action | Adenosine A1 receptor antagonist |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one |
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| INCHI | InChI=1S/C23H25N3O2/c27-17-14-19-10-4-6-15-25(19)22(28)13-12-20-21-11-5-7-16-26(21)24-23(20)18-8-2-1-3-9-18/h1-3,5,7-9,11-13,16,19,27H,4,6,10,14-15,17H2/b13-12+/t19-/m1/s1 |
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| InChi Key | OPLOPFHUHFGKMJ-JXOMPUQVSA-N |
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| Canonical SMILES | OCC[C@H]1CCCCN1C(=O)/C=C/c1c(nn2c1cccc2)c1ccccc1 |
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| Isomeric SMILES | C1CCN([C@H](C1)CCO)C(=O)/C=C/C2=C3C=CC=CN3N=C2C4=CC=CC=C4 |
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| PubChem CID | 6439091 |
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| Molecular Weight | 375.5 |
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