FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
Information
FL-411 FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy -associated cell death (ACD) by blocking BRD4-AMPK interaction.
Targets
BRD4(1) (Cell-free assay) 0.43 μM
Associated Targets(Human)
BRD4TchemBromodomain-containing protein 4 (6 Activities)
