Click Here for 5% Off Your First Aladdin Purchase!

Fludarabine - 98%, high purity , CAS No.21679-14-1, Inhibitor of ribonucleotide reductase catalytic subunit M1;Inhibitor of ribonucleotide reductase regulatory subunit M2

Specifications & Purity:  98%
Item Number
F122998
Grouped product items
SKUSizeAvailabilityPrice Qty
F122998-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$155.90
F122998-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$702.90
F122998-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,527.90
F122998-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$11,372.90
F122998-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$51,175.90

DNA synthesis inhibitor. Prodrug converted to active metabolite F-ara-A.

Basic Description

SynonymsFludarabine|21679-14-1|F-Ara-A|2-Fluoro Ara-A|(2R,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol|Fludarabinum|9-beta-D-Arabinofuranosyl-2-fluoroadenine|Fludarabine [INN]|Fludarabina|Fluradosa|2-F-ara-A|NSC 118218|Fl
Specifications & Purity98%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionInhibitor of ribonucleotide reductase catalytic subunit M1;Inhibitor of ribonucleotide reductase regulatory subunit M2

Associated Targets

RRM1 Tclin Ribonucleoside-diphosphate reductase large subunit 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RRM2 Tclin Ribonucleoside-diphosphate reductase subunit M2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
INCHI InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
InChi Key HBUBKKRHXORPQB-FJFJXFQQSA-N
Canonical SMILES C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N
Isomeric SMILES C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)F)N
WGK Germany 3
PubChem CID 657237
Molecular Weight 285.23
Beilstein 1225932

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
G1516071Certificate of AnalysisMar 07, 2023 F122998
E2415052Certificate of AnalysisMay 30, 2022 F122998
F2316128Certificate of AnalysisMay 30, 2022 F122998
G2208234Certificate of AnalysisMay 30, 2022 F122998
G2208313Certificate of AnalysisMay 30, 2022 F122998
G2208314Certificate of AnalysisMay 30, 2022 F122998
G2208315Certificate of AnalysisMay 30, 2022 F122998
G2208316Certificate of AnalysisMay 30, 2022 F122998

Chemical and Physical Properties

SolubilitySoluble in water (<1 mg/mL at 25 °C), DMSO (57 mg/mL at 25 °C), and ethanol (<1 mg/mL at 25 °C).
SensitivityHygroscopic
Specific Rotation[α]18° (C=0.1,EtOH)
Melt Point(°C)260 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements H302
Precautionary Statements P501,P264,P270,P330,P301+P317
WGK Germany 3
Merck Index 4126

Related Documents

Product Questions

Product Questions

Sign In Hover me Please sign in to submit a question
No questions yet. Be the first to ask the question!

Reviews

Customer Reviews

Calculator