Fluoxetine HCl - ≥98%(HPLC), high purity , Serotonin transporter inhibitor, CAS No.56296-78-7, Serotonin transporter inhibitor

  • ≥98%(HPLC)
Item Number
F131623
Grouped product items
SKUSizeAvailabilityPrice Qty
F131623-1g
1g
In stock
$66.90
F131623-5g
5g
In stock
$200.90
F131623-25g
25g
In stock
$902.90
F131623-100g
100g
In stock
$3,247.90
F131623-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$14,612.90

5-HT reuptake inhibitor

Basic Description

SynonymsFlunil | Fluoxetine (as hydrochloride) | Fluxen | Pragmaten | Prozac 20 | CPD000058452 | Fluoxil | Fluox-Puren | HY-B0102A | Opera_ID_1538 | SMR000058452 | Fluxil | HMS1569H03 | CHEBI:145458 | Deproxin | EINECS 260-101-2 | MLS002222264 | Nopres | Fluoxeti
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsFluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionSerotonin transporter inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
An ST (SERT) inhibitor.


application:

Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. It is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder and premenstrual dysphoric disorder (PMDD).


product description:

Fluoxetine hydrochloride is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs).

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1D Tchem Casein kinase I delta (4546 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
S1PR1 Tclin Sphingosine 1-phosphate receptor Edg-1 (5806 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C5AR1 Tclin C5a anaphylatoxin chemotactic receptor (2677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CX3CR1 Tchem C-X3-C chemokine receptor 1 (1686 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FPR2 Tchem Lipoxin A4 receptor (3472 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FFAR4 Tchem G-protein coupled receptor 120 (2999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UBE2N Tchem Ubiquitin-conjugating enzyme E2 N (1570 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPR35 Tchem G-protein coupled receptor 35 (2643 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRIM24 Tchem Transcription intermediary factor 1-alpha (2087 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRPF1 Tchem Peregrin (2217 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aplnr Apelin receptor (201 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gpr119 Glucose-dependent insulinotropic receptor (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NET Transporter (332 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488183615
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183615
IUPAC Name N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride
INCHI InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
InChi Key GIYXAJPCNFJEHY-UHFFFAOYSA-N
Canonical SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
Isomeric SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
WGK Germany 3
RTECS UI4050000
PubChem CID 62857
Molecular Weight 345.79
Reaxy-Rn 6759273

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
C2324684Certificate of AnalysisJan 02, 2023 F131623
C2324766Certificate of AnalysisJan 02, 2023 F131623
C2324770Certificate of AnalysisJan 02, 2023 F131623
C2324771Certificate of AnalysisJan 02, 2023 F131623
C2324774Certificate of AnalysisJan 02, 2023 F131623
C2324779Certificate of AnalysisJan 02, 2023 F131623
C2324782Certificate of AnalysisJan 02, 2023 F131623
C2324834Certificate of AnalysisJan 02, 2023 F131623
I2222530Certificate of AnalysisNov 13, 2021 F131623

Chemical and Physical Properties

SolubilitySoluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol.
Melt Point(°C)159 °C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H302:Harmful if swallowed

H318:Causes serious eye damage

H400:Very toxic to aquatic life

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 3
RTECS UI4050000
Reaxy-Rn 6759273

Related Documents

Citations of This Product

1. Lin Sheng, Yumeng Wei, Chao Pi, Ju Cheng, Zhilian Su, Yuanyuan Wang, Tao Chen, Jie Wen, Yuxun Wei, Jingwen Ma, Jia Tang, Huiyang Liu, Zerong Liu, Hongping Shen, Ying Zuo, Wenwu Zheng, Ling Zhao.  (2023)  Preparation and Evaluation of Curcumin Derivatives Nanoemulsion Based on Turmeric Extract and Its Antidepressant Effect.  International Journal of Nanomedicine,      [PMID:38162571] [10.2147/IJN.S430769]
2. Zhou Can, Zhou Yiming, Liang Yu, Chen Lijuan, Liu Li, Wei Fang, Li Guolin.  (2023)  Fluoxetine Promotes Longevity via Reactive Oxygen Species in Caenorhabditis elegans.  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES,  79  (1):   [PMID:37708096] [10.1093/gerona/glad220]
3. Shangmin Yu, Xinying Wang, Linlin Lv, Tongyan Liu, Qingxiang Guan.  (2023)  Borneol-modified PEGylated graphene oxide as a nanocarrier for brain-targeted delivery of ginsenoside Rg1 against depression.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  643  (123284).  [PMID:37527732] [10.1016/j.ijpharm.2023.123284]
4. Weiwei Wang, Xin Li, Qiuhui Qian, Jin Yan, Haishan Huang, Xuedong Wang, Huili Wang.  (2023)  Mechanistic exploration on neurodevelopmental toxicity induced by upregulation of alkbh5 targeted by triclosan exposure to larval zebrafish.  JOURNAL OF HAZARDOUS MATERIALS,  457  (131831).  [PMID:37320907] [10.1016/j.jhazmat.2023.131831]
5. Jiaqi Xie, Yihong Li, Yulu Liang, Hongqian Kui, Can Wang, Jianmei Huang.  (2023)  Integration of non-targeted metabolomics with network pharmacology deciphers the anxiolytic mechanisms of Platycladi Semen extracts in CUMS mice.  JOURNAL OF ETHNOPHARMACOLOGY,  315  (116571).  [PMID:37201666] [10.1016/j.jep.2023.116571]
6. Jiang Chuan, Wang Hua, Qi Jiaying, Li Jinghan, He Qianqian, Wang Chaonan, Gao Yonggang.  (2022)  Antidepressant effects of cherry leaf decoction on a chronic unpredictable mild stress rat model based on the Glu/GABA-Gln metabolic loop.  METABOLIC BRAIN DISEASE,  37  (8): (2883-2901).  [PMID:36181653] [10.1007/s11011-022-01081-7]
7. Zhuo Rengong, Cheng Xiaoling, Luo Lili, Yang Luying, Zhao Yun, Zhou Yu, Peng Lu, Jin Xin, Cui Lishan, Liu Feng, Yang Lichao.  (2022)  Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.  PHARMACOLOGY,  107  (5-6): (281-289).  [PMID:35325888] [10.1159/000520990]
8. Chai Yuhui, Cai Yawen, Fu Yu, Wang Yingdi, Zhang Yiming, Zhang Xue, Zhu Lingpeng, Miao Mingxing, Yan Tianhua.  (2022)  Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.  Frontiers in Pharmacology,  13    [PMID:35496273] [10.3389/fphar.2022.812362]
9. Yiwei Liu, Xiaopeng Hu, Yide Xia, Faqiong Zhao, Baizhao Zeng.  (2022)  A novel ratiometric electrochemical sensor based on dual-monomer molecularly imprinted polymer and Pt/Co3O4 for sensitive detection of chlorpromazine hydrochloride.  ANALYTICA CHIMICA ACTA,  1190  (339245).  [PMID:34857150] [10.1016/j.aca.2021.339245]
10. Shangmin Yu, Shan Liu, Ning Wang, Di Yu, Meng Qin, Ji Wu, Qingxiang Guan.  (2021)  Novel insights into antidepressant mechanism of Kai Xin San formula: Inhibiting NLRP3 inflammasome activation by promoting autophagy.  PHYTOMEDICINE,  93  (153792).  [PMID:34735906] [10.1016/j.phymed.2021.153792]
11. Jiang Ning, Wang Haixia, Huang Hong, Lv Jingwei, Zeng Guirong, Wang Qiong, Bao Yu, Chen Ying, Liu Xinmin.  (2021)  The Antidepressant-Like Effects of Shen Yuan in a Chronic Unpredictable Mild Stress Rat Model.  Frontiers in Psychiatry,  12    [PMID:33584387] [10.3389/fpsyt.2021.622204]
12. Hang Mei, Huajing Liu, Qianqian Shang, Ying Dong, Stig Pedersen-Bjergaard, Chuixiu Huang, Xiantao Shen.  (2021)  Organic-solvent-free electromembrane extraction based on semi-interpenetrating polymer networks.  GREEN CHEMISTRY,  23  (4): (1782-1793).  [PMID:] [10.1039/D1GC00148E]
13. Yunfeng Zhou, Mingzhu Yan, Ruile Pan, Zhi Wang, Xue Tao, Chenchen Li, Tianji Xia, Xinmin Liu, Qi Chang.  (2021)  Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation.  JOURNAL OF ETHNOPHARMACOLOGY,  265  (113317).  [PMID:32861821] [10.1016/j.jep.2020.113317]
14. Rui Bai, Weifu Yan, Yong Xiao, Siqi Wang, Xiaochun Tian, Junpeng Li, Xiaofeng Xiao, Xiaoquan Lu, Feng Zhao.  (2020)  Acceleration of peroxymonosulfate decomposition by a magnetic MoS2/CuFe2O4 heterogeneous catalyst for rapid degradation of fluoxetine.  CHEMICAL ENGINEERING JOURNAL,  397  (125501).  [PMID:] [10.1016/j.cej.2020.125501]
15. Yunfeng Zhou, Xue Tao, Zhi Wang, Li Feng, Lisha Wang, Xinmin Liu, Ruile Pan, Yonghong Liao, Qi Chang.  (2019)  Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  20  (17): (4282).  [PMID:31480539] [10.3390/ijms20174282]
16. Yun-Feng Zhou, Li Feng, Xin-Min Liu, Xue Tao, Li-Sha Wang, Meng-Di Zhang, Zhi Wang, Shan-Guang Chen, Qi Chang.  (2019)  Urinary metabolic disturbance in the olfactory bulbectomized rats and the modulatory effects of fluoxetine.  LIFE SCIENCES,  234  (116751).  [PMID:31415771] [10.1016/j.lfs.2019.116751]
17. Libin Wan, Bin Lin, Ruiqin Zhu, Chuixiu Huang, Stig Pedersen-Bjergaard, Xiantao Shen.  (2019)  Liquid-Phase Microextraction or Electromembrane Extraction?.  ANALYTICAL CHEMISTRY,  91  (13): (8267–8273).  [PMID:31141346] [10.1021/acs.analchem.9b00946]
18. Li Yang, Liu Jing, Liu Xu, Su Cun-Jin, Zhang Qi-Lin, Wang Zhi-Hong, Cao Lei-Fang, Guo Xue-Yan, Huang Ya, Luo Weifeng, Liu Tong.  (2019)  Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain.  Neuroscience Bulletin,  35  (4): (661-672).  [PMID:30900142] [10.1007/s12264-019-00367-8]
19. Shujie Zhu, Shaowei Lei, Sisi Zhou, Lisha Jin, Su Zeng, Huidi Jiang, Hui Zhou.  (2019)  Luteolin shows antidepressant-like effect by inhibiting and downregulating plasma membrane monoamine transporter (PMAT, Slc29a4).  Journal of Functional Foods,  54  (440).  [PMID:] [10.1016/j.jff.2019.01.048]
20. Chang-An Geng, Tong-Hua Yang, Xiao-Yan Huang, Yun-Bao Ma, Xue-Mei Zhang, Ji-Jun Chen.  (2019)  Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors.  JOURNAL OF ETHNOPHARMACOLOGY,  232  (39).  [PMID:30543912] [10.1016/j.jep.2018.12.013]

References

1. Lin Sheng, Yumeng Wei, Chao Pi, Ju Cheng, Zhilian Su, Yuanyuan Wang, Tao Chen, Jie Wen, Yuxun Wei, Jingwen Ma, Jia Tang, Huiyang Liu, Zerong Liu, Hongping Shen, Ying Zuo, Wenwu Zheng, Ling Zhao.  (2023)  Preparation and Evaluation of Curcumin Derivatives Nanoemulsion Based on Turmeric Extract and Its Antidepressant Effect.  International Journal of Nanomedicine,      [PMID:38162571] [10.2147/IJN.S430769]
2. Zhou Can, Zhou Yiming, Liang Yu, Chen Lijuan, Liu Li, Wei Fang, Li Guolin.  (2023)  Fluoxetine Promotes Longevity via Reactive Oxygen Species in Caenorhabditis elegans.  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES,  79  (1):   [PMID:37708096] [10.1093/gerona/glad220]
3. Shangmin Yu, Xinying Wang, Linlin Lv, Tongyan Liu, Qingxiang Guan.  (2023)  Borneol-modified PEGylated graphene oxide as a nanocarrier for brain-targeted delivery of ginsenoside Rg1 against depression.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  643  (123284).  [PMID:37527732] [10.1016/j.ijpharm.2023.123284]
4. Weiwei Wang, Xin Li, Qiuhui Qian, Jin Yan, Haishan Huang, Xuedong Wang, Huili Wang.  (2023)  Mechanistic exploration on neurodevelopmental toxicity induced by upregulation of alkbh5 targeted by triclosan exposure to larval zebrafish.  JOURNAL OF HAZARDOUS MATERIALS,  457  (131831).  [PMID:37320907] [10.1016/j.jhazmat.2023.131831]
5. Jiaqi Xie, Yihong Li, Yulu Liang, Hongqian Kui, Can Wang, Jianmei Huang.  (2023)  Integration of non-targeted metabolomics with network pharmacology deciphers the anxiolytic mechanisms of Platycladi Semen extracts in CUMS mice.  JOURNAL OF ETHNOPHARMACOLOGY,  315  (116571).  [PMID:37201666] [10.1016/j.jep.2023.116571]
6. Jiang Chuan, Wang Hua, Qi Jiaying, Li Jinghan, He Qianqian, Wang Chaonan, Gao Yonggang.  (2022)  Antidepressant effects of cherry leaf decoction on a chronic unpredictable mild stress rat model based on the Glu/GABA-Gln metabolic loop.  METABOLIC BRAIN DISEASE,  37  (8): (2883-2901).  [PMID:36181653] [10.1007/s11011-022-01081-7]
7. Zhuo Rengong, Cheng Xiaoling, Luo Lili, Yang Luying, Zhao Yun, Zhou Yu, Peng Lu, Jin Xin, Cui Lishan, Liu Feng, Yang Lichao.  (2022)  Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.  PHARMACOLOGY,  107  (5-6): (281-289).  [PMID:35325888] [10.1159/000520990]
8. Chai Yuhui, Cai Yawen, Fu Yu, Wang Yingdi, Zhang Yiming, Zhang Xue, Zhu Lingpeng, Miao Mingxing, Yan Tianhua.  (2022)  Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.  Frontiers in Pharmacology,  13    [PMID:35496273] [10.3389/fphar.2022.812362]
9. Yiwei Liu, Xiaopeng Hu, Yide Xia, Faqiong Zhao, Baizhao Zeng.  (2022)  A novel ratiometric electrochemical sensor based on dual-monomer molecularly imprinted polymer and Pt/Co3O4 for sensitive detection of chlorpromazine hydrochloride.  ANALYTICA CHIMICA ACTA,  1190  (339245).  [PMID:34857150] [10.1016/j.aca.2021.339245]
10. Shangmin Yu, Shan Liu, Ning Wang, Di Yu, Meng Qin, Ji Wu, Qingxiang Guan.  (2021)  Novel insights into antidepressant mechanism of Kai Xin San formula: Inhibiting NLRP3 inflammasome activation by promoting autophagy.  PHYTOMEDICINE,  93  (153792).  [PMID:34735906] [10.1016/j.phymed.2021.153792]
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Solution Calculators