Fluphenazine hydrochloride - 95%, high purity , Dopamine D2 receptor antagonist, CAS No.146-56-5, Dopamine D2 receptor antagonist

Item Number

F276205

• Synonyms: 1-(2-Hydroxyethyl)-4-(3-(2-trifluoromethyl-10-phenothiazinylpropyl)piperazine dihydrochloride | 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-, dihydrochloride | CCRIS 4032 | 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-ph
• Specifications & Purity: ≥95%
• Biochemical and Physiological Mechanisms: Potent dopamine D 2 /D 1 receptor antagonist (K i values are 0.4 (D 2 ), 2.3 (D 1 ), 1.4 (D 3 ), 7.1 (D 4 ) and 25 nM (D 5 )). Inhibits dopamine-induced increases in adenylate cyclase activity (K i = 9 nM). Antipsychotic. Active in vivo .
• Source: Synthetic
• Storage Temp: Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Action Type: ANTAGONIST
• Mechanism of action: Dopamine D2 receptor antagonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product description：

Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.