Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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F421699-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Potent dopamine D 2 /D 1 receptor antagonist
Synonyms | Fluphenazine dihydrochloride | Fluphenazine hydrochloride | 146-56-5 | Prolixin | Permitil | Anatensol | Fluphenazine (dihydrochloride) | Tensofin | Moditen | FLUPHENAZINE HCL | Squibb 4918 | Calmansial | Fluphenazine chloride | Dapotum | OMCA | Flufenazin | Lyorodin | Liogen | Fluorophenaz |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Potent dopamine D 2 /D 1 receptor antagonist (K i values are 0.4 (D 2 ), 2.3 (D 1 ), 1.4 (D 3 ), 7.1 (D 4 ) and 25 nM (D 5 )). Inhibits dopamine-induced increases in adenylate cyclase activity (K i = 9 nM). Antipsychotic. Active in vivo . |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
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IUPAC Name | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;dihydrochloride |
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INCHI | InChI=1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H |
InChi Key | MBHNWCYEGXQEIT-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl |
Isomeric SMILES | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl |
PubChem CID | 67356 |
Molecular Weight | 510.44 |
Enter Lot Number to search for COA:
Melt Point(°C) | 227 °C |
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Pictogram(s) | GHS06, GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H301:Toxic if swallowed H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H330:Fatal if inhaled H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H370:Causes damage to organs H362:May cause harm to breast-fed children |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
Merck Index | 4189 |