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Fmoc-Leu-OH - 98%, high purity , CAS No.35661-60-0, Agonist of Peroxisome proliferator-activated receptor-γ

  • Moligand™
  • ≥98%
Item Number
F100808
Grouped product items
SKUSizeAvailabilityPrice Qty
F100808-5g
5g
In stock
$23.90
F100808-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$43.90
F100808-25g
25g
In stock
$97.90
F100808-100g
100g
In stock
$349.90
F100808-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,574.90

Increases intracellular Ca2+levels

Basic Description

SynonymsFmoc-L-leucine|35661-60-0|Fmoc-Leu-OH|Fmoc-L-Leu-OH|N-Fmoc-L-leucine|fmoc-leucine|N-(9-fluorenylmethoxycarbonyl)-L-leucine|N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine|(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid|n-(fluorenyl-9-me
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsAnti-inflammatory agent; increases intracellular Ca2+levels.
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of Peroxisome proliferator-activated receptor-γ

Associated Targets

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CTNS Tbio Cystinosin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC17A5 Tbio Sialin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SNCA Tchem Alpha-synuclein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H2 Tchem Oxysterols receptor LXR-beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BRCA1 Tchem Breast cancer type 1 susceptibility protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AHR Tclin Aryl hydrocarbon receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
INCHI InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
InChi Key CBPJQFCAFFNICX-IBGZPJMESA-N
Canonical SMILES CC(C)CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES CC(C)C[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
WGK Germany 3
PubChem CID 1549133
Molecular Weight 353.41
Beilstein 2178254
Reaxy-Rn 2178254

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
C1912133Certificate of AnalysisDec 14, 2022 F100808
H2401033Certificate of AnalysisJun 16, 2022 F100808
I2215178Certificate of AnalysisJun 16, 2022 F100808
I2215179Certificate of AnalysisJun 16, 2022 F100808
I2215193Certificate of AnalysisJun 16, 2022 F100808
I2215194Certificate of AnalysisJun 16, 2022 F100808

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 35.34, Max Conc. mM: 100 with gentle warming
Specific Rotation[α]-25 ° (C=1, DMF)
Melt Point(°C)153-157°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 2178254

Related Documents

References

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