Grouped product items

SKU

Size

Availability

Price

Qty

F105470-5g

In stock

$15.90

F105470-10g

10g

Available within 8-12 weeks(?)

$27.90

F105470-25g

25g

In stock

$45.90

F105470-100g

100g

Available within 4-8 weeks(?)

$164.90

F105470-500g

500g

Available within 4-8 weeks(?)

$738.90

Basic Description

Synonyms	EN300-74033 \| BRD-K24518485-001-01-0 \| fluoren-9-ylmethyl N-(1-carboxy-2-methylbutyl)carbamate \| Z1123720061 \| N-.alpha.-Fmoc-L-isoleucine \| N-Fmoc-Ile-OH ( N-Fmoc-L-isoleucine) \| DTXSID801315561 \| CS-W020667 \| Fmoc-L-isoleucine \| SCHEMBL119497 \| L-Isoleu
Specifications & Purity	≥99%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	application： N-Fmoc-L-isoleucine is an unnatural amino acid used for peptidomimetics. It is also used as a pharmaceutical intermediate

Associated Targets(Human)

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SW480 (6023 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

Discover Target: MEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCD-841CoN (99 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

surA Chaperone SurA (18 Activities)

Discover Target: surA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2S,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylpentanoic acid
INCHI	InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1
InChi Key	QXVFEIPAZSXRGM-DJJJIMSYSA-N
Canonical SMILES	CCC(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES	CC[C@H](C)[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
WGK Germany	3
PubChem CID	2724629
Molecular Weight	353.41
Beilstein	4716717

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
A1917035	Certificate of Analysis	Nov 15, 2022	F105470
C2415108	Certificate of Analysis	Sep 30, 2021	F105470
D2301013	Certificate of Analysis	Sep 30, 2021	F105470
D2301014	Certificate of Analysis	Sep 30, 2021	F105470
H2325072	Certificate of Analysis	Sep 30, 2021	F105470
I2423608	Certificate of Analysis	Sep 30, 2021	F105470

Chemical and Physical Properties

Solubility	Soluble in methanol (very faint turbidity).
Specific Rotation[α]	-12±1°, c = 1% in DMF
Melt Point(°C)	144-149°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help.
WGK Germany	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhanpeng Ren, Jianying Wang, Chenglong Xue, Minghua Deng, Haiyang Yu, Tianci Lin, Jiayuan Zheng, Rongxiang He, Xianbao Wang, Jinhua Li. (2023) Ultrahighly Sensitive and Selective Glutathione Sensor Based on Carbon Dot-Functionalized Solution-Gate Graphene Transistor. ANALYTICAL CHEMISTRY, 95 (48): (17750–17758). [PMID:37971943] [10.1021/acs.analchem.3c03656]

References

1. Chiao-Ting Yen,Tsong-Long Hwang,Yang-Chang Wu,Pei-Wen Hsieh. (2008-12-27) Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents.. European journal of medicinal chemistry, 44 ((5)): (1933-1940). [PMID:19110343]
2. K R Sunil Kumar,Takashi Kamei,Tuyoshi Fukaminato,Nobuyuki Tamaoki. (2014-04-01) Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.. ACS nano, 8 ((5)): (4157-4165). [PMID:24680285]
3. Moise Ndao,Gil Goobes,Prashant S Emani,Gary P Drobny. (2016-04-05) A REDOR ssNMR Investigation of the Role of an N-Terminus Lysine in R5 Silica Recognition.. Langmuir : the ACS journal of surfaces and colloids, 34 ((29)): (8678-8684). [PMID:27039990]
4. Stefan Eissler,Markus Kley,Dirk Bächle,Günther Loidl,Thomas Meier,Daniel Samson. (2017-06-22) Substitution determination of Fmoc-substituted resins at different wavelengths.. Journal of peptide science : an official publication of the European Peptide Society, 23 ((10)): (757-762). [PMID:28635051]
5. Zdenek Kukacka,Marius Iurascu,Loredana Lupu,Hendrik Rusche,Mary Murphy,Lorenzo Altamore,Fabio Borri,Stefan Maeser,Anna Maria Papini,Julia Hennermann,Michael Przybylski. (2018-02-24) Antibody Epitope of Human α-Galactosidase\u2005A Revealed by Affinity Mass Spectrometry: A Basis for Reversing Immunoreactivity in Enzyme Replacement Therapy of Fabry Disease.. ChemMedChem, 13 ((9)): (909-915). [PMID:29473701]
6. R Ashton Lavoie,Alice di Fazio,R Kevin Blackburn,Michael B Goshe,Ruben G Carbonell,Stefano Menegatti. (2019-04-11) Targeted Capture of Chinese Hamster Ovary Host Cell Proteins: Peptide Ligand Discovery.. International journal of molecular sciences, 20 ((7)): [PMID:30965558]
7. Karthik Nadendla,Bhagyesh R Sarode,Simon H Friedman. (2019-05-24) Hydrophobic Tags for Highly Efficient Light-Activated Protein Release.. Molecular pharmaceutics, 16 ((7)): (2922-2928). [PMID:31117739]
8. Yu-I Hsu,Tetsuji Yamaoka. (2019-08-21) Improved exposure of bioactive peptides to the outermost surface of the polylactic acid nanofiber scaffold.. Journal of biomedical materials research. Part B, Applied biomaterials, 108 ((4)): (1274-1280). [PMID:31429188]
9. R Ashton Lavoie,Alice di Fazio,Taufika Islam Williams,Ruben Carbonell,Stefano Menegatti. (2019-10-28) Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis.. Biotechnology and bioengineering, 117 ((2)): (438-452). [PMID:31654407]
10. Michał Padjasek,Maciej Maciejczyk,Michał Nowakowski,Olga Kerber,Maciej Pyrka,Wiktor Koźmiński,Artur Krężel. (2019-12-18) Metal Exchange in the Interprotein ZnII -Binding Site of the Rad50 Hook Domain: Structural Insights into CdII -Induced DNA-Repair Inhibition.. Chemistry (Weinheim an der Bergstrasse, Germany), 26 ((15)): (3297-3313). [PMID:31846102]
11. Zhanpeng Ren, Jianying Wang, Chenglong Xue, Minghua Deng, Haiyang Yu, Tianci Lin, Jiayuan Zheng, Rongxiang He, Xianbao Wang, Jinhua Li. (2023) Ultrahighly Sensitive and Selective Glutathione Sensor Based on Carbon Dot-Functionalized Solution-Gate Graphene Transistor. ANALYTICAL CHEMISTRY, 95 (48): (17750–17758). [PMID:37971943] [10.1021/acs.analchem.3c03656]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Fmoc-lle-OH - 99%, high purity , CAS No.71989-23-6

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator