Click Here for 5% Off Your First Aladdin Purchase!

Folic acid - ≥97%(HPLC), high purity , CAS No.59-30-3

  • Moligand™
  • ≥97%(HPLC)
Item Number
F103635
Grouped product items
SKUSizeAvailabilityPrice Qty
F103635-5g
5g
In stock
$17.90
F103635-10g
10g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$27.90
F103635-25g
25g
In stock
$52.90
F103635-100g
100g
In stock
$188.90
F103635-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$423.90
F103635-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$761.90

Basic Description

Synonymsfolic acid|59-30-3|Pteroylglutamic acid|Folate|Vitamin M|Folacin|PteGlu|Folacid|Vitamin B9|Vitamin Bc|Folicet|Folvite|Incafolic|Folettes|Foliamin|Folipac|Folsan|Millafol|Acifolic|Cytofol|Pteroyl-L-glutamic acid|Folsaure|Folbal|Folsav|Foldine|Vitamin Be|Mi
Specifications & PurityMoligand™, ≥97%(HPLC)
Biochemical and Physiological MechanismsFolic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidyli
Shipped InNormal
GradeMoligand™

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CXCL14 Tbio C-X-C motif chemokine 14 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CNR1 Tclin Cannabinoid receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DHFR Tclin Dihydrofolate reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SNCA Tchem Alpha-synuclein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AKR1B1 Tclin Aldose reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MLNR Tchem Motilin receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488202824
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488202824
IUPAC Name (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
INCHI InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChi Key OVBPIULPVIDEAO-LBPRGKRZSA-N
Canonical SMILES C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
Isomeric SMILES C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
RTECS LP5425000
PubChem CID 135398658
Molecular Weight 441.4
Reaxy-Rn 100781

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

19 results found

Lot NumberCertificate TypeDateItem
J2016033Certificate of AnalysisAug 16, 2024 F103635
D2410048Certificate of AnalysisMay 08, 2024 F103635
D2415373Certificate of AnalysisApr 29, 2024 F103635
G2419025Certificate of AnalysisApr 29, 2024 F103635
D2303898Certificate of AnalysisApr 10, 2023 F103635
D2303900Certificate of AnalysisApr 10, 2023 F103635
D2303949Certificate of AnalysisApr 10, 2023 F103635
D2303899Certificate of AnalysisApr 09, 2023 F103635
D2303901Certificate of AnalysisApr 09, 2023 F103635
D2303911Certificate of AnalysisApr 09, 2023 F103635
D2303897Certificate of AnalysisApr 09, 2023 F103635
H2408065Certificate of AnalysisApr 09, 2023 F103635
L2301153Certificate of AnalysisDec 18, 2021 F103635
L2115599Certificate of AnalysisDec 18, 2021 F103635
G2230070Certificate of AnalysisDec 18, 2021 F103635
G2230069Certificate of AnalysisDec 18, 2021 F103635
G2230068Certificate of AnalysisDec 18, 2021 F103635
G2230067Certificate of AnalysisDec 18, 2021 F103635
G2230066Certificate of AnalysisDec 18, 2021 F103635

more

Chemical and Physical Properties

Sensitivitylight sensitiv
Specific Rotation[α]20° (C=1,NaOH sol.)
Melt Point(°C)250°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

RTECS LP5425000
Reaxy-Rn 100781
Merck Index 4221

Related Documents

References

1. H Firat,M C Giarratana,L Kobari,A Poloni,S Bouchet,M Labopin,N C Gorin,L Douay.  (1998-06-05)  Comparison of CD34+ bone marrow cells purified by immunomagnetic and immunoadsorption cell separation techniques..  Bone marrow transplantation,  21  ((9)): (933-938).  [PMID:9613787]
2. Thommey P Thomas,Istvan J Majoros,Alina Kotlyar,Jolanta F Kukowska-Latallo,Anna Bielinska,Andrzej Myc,James R Baker.  (2005-05-27)  Targeting and inhibition of cell growth by an engineered dendritic nanodevice..  Journal of medicinal chemistry,  48  ((11)): (3729-3735).  [PMID:15916424]
3. Alexis Nzila.  (2006-09-26)  Inhibitors of de novo folate enzymes in Plasmodium falciparum..  Drug discovery today,  11  ((19-20)): (939-944).  [PMID:16997145]
4. Nigel Greene,Lilia Fisk,Russell T Naven,Reine R Note,Mukesh L Patel,Dennis J Pelletier.  (2010-06-18)  Developing structure-activity relationships for the prediction of hepatotoxicity..  Chemical research in toxicology,  23  ((7)): (1215-1222).  [PMID:20553011]
5. Gianni Ciofani,Vittoria Raffa,Arianna Menciassi,Alfred Cuschieri.  (2008-01-01)  Folate Functionalized Boron Nitride Nanotubes and their Selective Uptake by Glioblastoma Multiforme Cells: Implications for their Use as Boron Carriers in Clinical Boron Neutron Capture Therapy..  Nanoscale research letters,  ((2)): (113-121).  [PMID:20596476]
6. Sean Ekins,Antony J Williams,Jinghai J Xu.  (2010-09-17)  A predictive ligand-based Bayesian model for human drug-induced liver injury..  Drug metabolism and disposition: the biological fate of chemicals,  38  ((12)): (2302-2308).  [PMID:20843939]
7. Amir Al-Dabagh,Scott A Davis,Megan A Kinney,Karen Huang,Steven R Feldman.  (2013-04-12)  The effect of folate supplementation on methotrexate efficacy and toxicity in psoriasis patients and folic acid use by dermatologists in the USA..  American journal of clinical dermatology,  14  ((3)): (155-161).  [PMID:23575550]
8. Timothy Craig Allen.  (2013-06-01)  Targeted molecular therapy for lung cancer: exuberance reestablished..  Archives of pathology & laboratory medicine,  137  ((6)): (747-747).  [PMID:23721267]
9. Yarlini Balarajan,S V Subramanian,Wafaie W Fawzi.  (2013-06-14)  Maternal iron and folic acid supplementation is associated with lower risk of low birth weight in India..  The Journal of nutrition,  143  ((8)): (1309-1315).  [PMID:23761647]
10. Alvin Nursalim,Parlindungan Siregar,Indah S Widyahening.  (2013-06-19)  Effect of folic acid, vitamin B6 and vitamin B12 supplementation on mortality and cardiovascular complication among patients with chronic kidney disease: an evidence-based case report..  Acta medica Indonesiana,  45  ((2)): (150-156).  [PMID:23770797]
11. Zhiyao He,Yiyi Yu,Ying Zhang,Yongdong Yan,Yu Zheng,Jun He,Yongmei Xie,Gu He,Yuquan Wei,Xiangrong Song.  (2013-06-28)  Gene delivery with active targeting to ovarian cancer cells mediated by folate receptor alpha..  Journal of biomedical nanotechnology,  ((5)): (833-844).  [PMID:23802413]
12. Apolline Imbard,Jean-François Benoist,Henk J Blom.  (2013-09-21)  Neural tube defects, folic acid and methylation..  International journal of environmental research and public health,  10  ((9)): (4352-4389).  [PMID:24048206]
13. P M Tedeschi,E K Markert,M Gounder,H Lin,D Dvorzhinski,S C Dolfi,L L-Y Chan,J Qiu,R S DiPaola,K M Hirshfield,L G Boros,J R Bertino,Z N Oltvai,A Vazquez.  (2013-10-26)  Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells..  Cell death & disease,  (e877-e877).  [PMID:24157871]
14. András Jeney.  (2013-10-29)  [History of the therapy of pernicious anemia]..  Orvosi hetilap,  154  ((44)): (1754-1758).  [PMID:24161600]
15. Sachin Yadav,Swati Gupta.  (2013-11-08)  Development and in vitro characterization of docetaxel-loaded ligand appended solid fat nanoemulsions for potential use in breast cancer therapy..  Artificial cells, nanomedicine, and biotechnology,  43  ((2)): (93-102).  [PMID:24195582]
16. Cristina Müller,Maruta Bunka,Josefine Reber,Cindy Fischer,Konstantin Zhernosekov,Andreas Türler,Roger Schibli.  (2013-11-08)  Promises of cyclotron-produced 44Sc as a diagnostic match for trivalent β--emitters: in vitro and in vivo study of a 44Sc-DOTA-folate conjugate..  Journal of nuclear medicine : official publication, Society of Nuclear Medicine,  54  ((12)): (2168-2174).  [PMID:24198390]
17. Collin J Weber,Susan Müller,Susan A Safley,Kereen B Gordon,Praveen Amancha,Francois Villinger,Vernon M Camp,Malgorzata Lipowska,Jyotirmay Sharma,Cristina Müller,Roger Schibli,Philip S Low,Christopher P Leamon,Raghuveer K Halkar.  (2013-11-12)  Expression of functional folate receptors by human parathyroid cells..  Surgery,  154  ((6)): (1385-1393).  [PMID:24206618]
18. Jack Metz.  (2013-12-05)  Haematological implications of folate food fortification..  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,  103  ((12 Suppl 1)): (978-981).  [PMID:24300642]
19. Aline H Guariento,Kelly S Furtado,Aline de Conti,Adriana Campos,Eduardo Purgatto,Jéssica Carrilho,Elvira Maria Guerra Shinohara,Volodymyr Tryndyak,Tao Han,James C Fuscoe,Sharon A Ross,Frederick A Beland,Igor P Pogribny,Fernando S Moreno.  (2013-12-05)  Transcriptomic responses provide a new mechanistic basis for the chemopreventive effects of folic acid and tributyrin in rat liver carcinogenesis..  International journal of cancer,  135  ((1)): (7-18).  [PMID:24302446]
20. Barbara Anne Jennings,Gavin Willis.  (2014-03-13)  How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy..  Cancer letters,  356  ((2 Pt A)): (224-230).  [PMID:24614284]
21. Myra A Carpenter,Alin John,Matthew R Weir,Stephen R Smith,Lawrence Hunsicker,Bertram L Kasiske,John W Kusek,Andrew Bostom,Anastasia Ivanova,Andrew S Levey,Scott Solomon,Todd Pesavento,Daniel E Weiner.  (2014-03-15)  BP, cardiovascular disease, and death in the Folic Acid for Vascular Outcome Reduction in Transplantation trial..  Journal of the American Society of Nephrology : JASN,  25  ((7)): (1554-1562).  [PMID:24627349]
22. Maika Kissei,Tomoo Itoh,Tomoya Narawa.  (2014-04-04)  Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter..  Drug metabolism and pharmacokinetics,  29  ((5)): (367-372).  [PMID:24695276]
23. Jian-Zhuang Tan,Yu-Ming Guo,Todd J Applegate,En-Cun Du,Xu Zhao.  (2014-04-15)  Dietary L-arginine modulates immunosuppression in broilers inoculated with an intermediate strain of infectious bursa disease virus..  Journal of the science of food and agriculture,  95  ((1)): (126-135).  [PMID:24728981]
24. Alan H Maurer,Philip Elsinga,Stefano Fanti,Binh Nguyen,Wim J G Oyen,Wolfgang A Weber.  (2014-04-16)  Imaging the folate receptor on cancer cells with 99mTc-etarfolatide: properties, clinical use, and future potential of folate receptor imaging..  Journal of nuclear medicine : official publication, Society of Nuclear Medicine,  55  ((5)): (701-704).  [PMID:24732155]
25. Wei-liang Ye,Jiang-bo Du,Bang-le Zhang,Ren Na,Yan-feng Song,Qi-bing Mei,Ming-gao Zhao,Si-yuan Zhou.  (2014-05-16)  Cellular uptake and antitumor activity of DOX-hyd-PEG-FA nanoparticles..  PloS one,  ((5)): (e97358-e97358).  [PMID:24828815]
26. Audrey J Gaskins,Janet W Rich-Edwards,Russ Hauser,Paige L Williams,Matthew W Gillman,Elizabeth S Ginsburg,Stacey A Missmer,Jorge E Chavarro.  (2014-06-06)  Maternal prepregnancy folate intake and risk of spontaneous abortion and stillbirth..  Obstetrics and gynecology,  124  ((1)): (23-31).  [PMID:24901281]
27. Peter Baxter.  (2014-06-14)  Valproate and folic acid in pregnancy: associations with autism..  Developmental medicine and child neurology,  56  ((7)): (604-604).  [PMID:24924417]
28. Roxana Daneshjou,Eric R Gamazon,Ben Burkley,Larisa H Cavallari,Julie A Johnson,Teri E Klein,Nita Limdi,Sara Hillenmeyer,Bethany Percha,Konrad J Karczewski,Taimour Langaee,Shitalben R Patel,Carlos D Bustamante,Russ B Altman,Minoli A Perera.  (2014-08-01)  Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans..  Blood,  124  ((14)): (2298-2305).  [PMID:25079360]
29. Henrik Kempe,Anna Parareda Pujolràs,Maria Kempe.  (2014-08-12)  Molecularly imprinted polymer nanocarriers for sustained release of erythromycin..  Pharmaceutical research,  32  ((2)): (375-388).  [PMID:25103333]
30. Shaolian Zhang,Haihua Bai,Jinmei Luo,Peihui Yang,Jiye Cai.  (2014-10-15)  A recyclable chitosan-based QCM biosensor for sensitive and selective detection of breast cancer cells in real time..  The Analyst,  139  ((23)): (6259-6265).  [PMID:25313373]
31. Inong R Gunanti,Geoffrey C Marks,Abdullah Al-Mamun,Kurt Z Long.  (2014-11-21)  Low serum vitamin B-12 and folate concentrations and low thiamin and riboflavin intakes are inversely associated with greater adiposity in Mexican American children..  The Journal of nutrition,  144  ((12)): (2027-2033).  [PMID:25411037]
32. Reiko Nishihara,Molin Wang,Zhi Rong Qian,Yoshifumi Baba,Mai Yamauchi,Kosuke Mima,Yasutaka Sukawa,Sun A Kim,Kentaro Inamura,Xuehong Zhang,Kana Wu,Edward L Giovannucci,Andrew T Chan,Charles S Fuchs,Shuji Ogino,Eva S Schernhammer.  (2014-11-21)  Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region..  The American journal of clinical nutrition,  100  ((6)): (1479-1488).  [PMID:25411283]
33. Estelle Cateau,Elodie Maisonneuve,Samuel Peguilhan,Nathalie Quellard,Yann Hechard,Marie-Helene Rodier.  (2014-12-03)  Stenotrophomonas maltophilia and Vermamoeba vermiformis relationships: bacterial multiplication and protection in amoebal-derived structures..  Research in microbiology,  165  ((10)): (847-851).  [PMID:25463386]
34. Van-Minh Le,Jing-Jing Wang,Ming Yuan,The-Long Nguyen,Gui-Fang Yin,Yuan-Hong Zheng,Wei-Bin Shi,Mei-Dong Lang,Lei-Ming Xu,Jian-Wen Liu.  (2015-02-14)  An investigation of antitumor efficiency of novel sustained and targeted 5-fluorouracil nanoparticles..  European journal of medicinal chemistry,  92  (882-889).  [PMID:25676729]
35. Suranjana Mukherjee,Joanna Kim,Olivia L Mooren,Stefanie T Shahan,Megan Cohan,John A Cooper.  (2015-02-28)  Role of cortactin homolog HS1 in transendothelial migration of natural killer cells..  PloS one,  10  ((2)): (e0118153-e0118153).  [PMID:25723543]
36. Anna E Stanhewicz,Lacy M Alexander,W Larry Kenney.  (2015-03-10)  Folic acid supplementation improves microvascular function in older adults through nitric oxide-dependent mechanisms..  Clinical science (London, England : 1979),  129  ((2)): (159-167).  [PMID:25748442]
37. Tor A Strand,Sunita Taneja,Tivendra Kumar,Mari S Manger,Helga Refsum,Chittaranjan S Yajnik,Nita Bhandari.  (2015-03-25)  Vitamin B-12, folic acid, and growth in 6- to 30-month-old children: a randomized controlled trial..  Pediatrics,  135  ((4)): (e918-e926).  [PMID:25802345]
38. Camila Simioni Vanzin,Caroline Paula Mescka,Bruna Donida,Tatiane Grazieli Hammerschimidt,Graziela S Ribas,Janaína Kolling,Emilene B Scherer,Laura Vilarinho,Célia Nogueira,Adriana Simon Coitinho,Moacir Wajner,Angela T S Wyse,Carmen Regla Vargas.  (2015-03-26)  Lipid, Oxidative and Inflammatory Profile and Alterations in the Enzymes Paraoxonase and Butyrylcholinesterase in Plasma of Patients with Homocystinuria Due CBS Deficiency: The Vitamin B12 and Folic Acid Importance..  Cellular and molecular neurobiology,  35  ((6)): (899-911).  [PMID:25805165]
39. Ilayaraja Muthuramu,Neha Singh,Ruhul Amin,Elena Nefyodova,Mirjam Debasse,Isa Van Horenbeeck,Frank Jacobs,Bart De Geest.  (2015-04-11)  Selective homocysteine-lowering gene transfer attenuates pressure overload-induced cardiomyopathy via reduced oxidative stress..  Journal of molecular medicine (Berlin, Germany),  93  ((6)): (609-618).  [PMID:25860230]
40. Qing Li,Maiko Kobayashi,Tomoyuki Kawada.  (2015-04-30)  Effect of carbamate pesticides on perforin, granzymes A-B-3/K, and granulysin in human natural killer cells..  International journal of immunopathology and pharmacology,  28  ((3)): (403-410).  [PMID:25921628]
41. Bing-Feng Zhang,Lei Xing,Peng-Fei Cui,Feng-Zhen Wang,Rong-Lin Xie,Jia-Liang Zhang,Mei Zhang,Yu-Jing He,Jin-Yuan Lyu,Jian-Bin Qiao,Bao-An Chen,Hu-Lin Jiang.  (2015-05-26)  Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine..  Biomaterials,  61  (178-189).  [PMID:26004233]
42. Rongqiang Liao,Shouhui Yi,Manshuo Liu,Wenling Jin,Bo Yang.  (2015-06-03)  Folic-Acid-Targeted Self-Assembling Supramolecular Carrier for Gene Delivery..  Chembiochem : a European journal of chemical biology,  16  ((11)): (1622-1628).  [PMID:26032689]
43. Luis Guzmán,Esteban F Durán-Lara,Wendy Donoso,Fabiane M Nachtigall,Leonardo S Santos.  (2015-06-18)  In Vivo Nanodetoxication for Acute Uranium Exposure..  Molecules (Basel, Switzerland),  20  ((6)): (11017-11033).  [PMID:26083036]
44. Vanesa Crujeiras,Luis Aldámiz-Echevarría,Jaime Dalmau,Isidro Vitoria,Fernando Andrade,Iria Roca,Rosaura Leis,Ana Fernandez-Marmiesse,María L Couce.  (2015-07-01)  Vitamin and mineral status in patients with hyperphenylalaninemia..  Molecular genetics and metabolism,  115  ((4)): (145-150).  [PMID:26123187]
45. Dawid Lewandowski,Piotr Ruszkowski,Anita Pińska,Grzegorz Schroeder,Joanna Kurczewska.  (2015-07-08)  SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity..  PloS one,  10  ((7)): (e0132541-e0132541).  [PMID:26151908]
46. Daniel E Roth,Alison D Gernand,Shaun K Morris,Brendon Pezzack,M Munirul Islam,Michelle C Dimitris,Shaila S Shanta,Stanley H Zlotkin,Andrew R Willan,Tahmeed Ahmed,Prakesh S Shah,Kellie E Murphy,Rosanna Weksberg,Sanaa Choufani,Rashed Shah,Abdullah Al Mahmud.  (2015-07-15)  Maternal vitamin D supplementation during pregnancy and lactation to promote infant growth in Dhaka, Bangladesh (MDIG trial): study protocol for a randomized controlled trial..  Trials,  16  (300-300).  [PMID:26169781]
47. Qin Zhao,Chengcheng Wang,Chengyuan Wang,Hui Guo,Zhihao Bao,Minhua Zhang,Peng Zhang.  (2015-07-23)  Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters..  Nature communications,  (7661-7661).  [PMID:26198469]
48. Yoshinori Yamada,Hiroshi Nakatani,Hisashi Yanaihara,Masahiro Omote.  (2015-08-05)  Phase I clinical trial of 99mTc-etarfolatide, an imaging agent for folate receptor in healthy Japanese adults..  Annals of nuclear medicine,  29  ((9)): (792-798).  [PMID:26238440]
49. Sergey Zakharov,Daniela Pelclova,Pavel Diblik,Pavel Urban,Pavel Kuthan,Olga Nurieva,Katerina Kotikova,Tomas Navratil,Martin Komarc,Jaromir Belacek,Zdenek Seidl,Manuela Vaneckova,Jaroslav A Hubacek,Ondrej Bezdicek,Jiri Klempir,Maksim Yurchenko,Evzen Ruzicka,Michal Miovsky,Barbara Janikova,Knut Erik Hovda.  (2015-09-15)  Long-term visual damage after acute methanol poisonings: Longitudinal cross-sectional study in 50 patients..  Clinical toxicology (Philadelphia, Pa.),  53  ((9)): (884-892).  [PMID:26364866]
50. Mahesh S Desai,Anna M Seekatz,Nicole M Koropatkin,Nobuhiko Kamada,Christina A Hickey,Mathis Wolter,Nicholas A Pudlo,Sho Kitamoto,Nicolas Terrapon,Arnaud Muller,Vincent B Young,Bernard Henrissat,Paul Wilmes,Thaddeus S Stappenbeck,Gabriel Núñez,Eric C Martens.  (2016-11-20)  A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility..  Cell,  167  ((5)): (1339-1353).  [PMID:27863247]
51. Xiaoyu Wang,Mingzhen Zhang,Shireen R L Flores,Regina R Woloshun,Chunhua Yang,Liangjie Yin,Ping Xiang,Xiaodong Xu,Michael D Garrick,Sadasivan Vidyasagar,Didier Merlin,James F Collins.  (2019-02-05)  Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis..  Molecular therapy : the journal of the American Society of Gene Therapy,  27  ((3)): (493-506).  [PMID:30713087]
52. Gerta Hoxhaj,Issam Ben-Sahra,Sophie E Lockwood,Rebecca C Timson,Vanessa Byles,Graham T Henning,Peng Gao,Laura M Selfors,John M Asara,Brendan D Manning.  (2019-03-09)  Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase..  Science (New York, N.Y.),  363  ((6431)): (1088-1092).  [PMID:30846598]
53. Wen Zhang,Yunwen Yang,Huiping Gao,Yue Zhang,Zhanjun Jia,Songming Huang.  (2019-09-26)  Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury..  Kidney & blood pressure research,  44  ((5)): (1002-1013).  [PMID:31553975]
54. Silvia Ferrè,Yingfeng Deng,Sarah C Huen,Christopher Y Lu,Philipp E Scherer,Peter Igarashi,Orson W Moe.  (2019-10-12)  Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation..  Kidney international,  96  ((6)): (1359-1373).  [PMID:31601454]
55. Haeri Choi,Sung Chun Cho,Young Wan Ha,Billie Ocampo,Shirley Park,Shiwen Chen,Christopher F Bennett,Jeehae Han,Ryan Rossner,Jong-Sun Kang,Yun-Ll Lee,Sang Chul Park,Matt Kaeberlein.  (2019-01-01)  DDS promotes longevity through a microbiome-mediated starvation signal..  Translational medicine of aging,  (64-69).  [PMID:32190786]
56. Daniel J Kim,Arvind Venkataraman,Priyanka Caroline Jain,Eleanor P Wiesler,Melody DeBlasio,Jonathan Klein,Stephanie S Tu,Seohyuk Lee,Ruslan Medzhitov,Akiko Iwasaki.  (2020-06-24)  Vitamin B12 and folic acid alleviate symptoms of nutritional deficiency by antagonizing aryl hydrocarbon receptor..  Proceedings of the National Academy of Sciences of the United States of America,  117  ((27)): (15837-15845).  [PMID:32571957]
57. Frédéric Bigey,Diego Segond,Anne Friedrich,Stephane Guezenec,Aurélie Bourgais,Lucie Huyghe,Nicolas Agier,Thibault Nidelet,Delphine Sicard.  (2020-12-11)  Evidence for Two Main Domestication Trajectories in Saccharomyces cerevisiae Linked to Distinct Bread-Making Processes..  Current biology : CB,  31  ((4)): (722-732).  [PMID:33301710]
58. Tzu-Heng Huang,Hsiao-Huang Chang,Yu-Ru Guo,Wei-Chiao Chang,Yi-Fan Chen.  (2021-11-14)  Vitamin B Mitigates Thoracic Aortic Dilation in Marfan Syndrome Mice by Restoring the Canonical TGF-β Pathway..  International journal of molecular sciences,  22  ((21)):   [PMID:34769168]
59. R Wendel Naumann,Robert L Coleman,Robert A Burger,Edward A Sausville,Elzbieta Kutarska,Sharad A Ghamande,Nashat Y Gabrail,Stephen E Depasquale,Elzbieta Nowara,Lucy Gilbert,Robert H Gersh,Michael G Teneriello,Wael A Harb,Panagiotis A Konstantinopoulos,Richard T Penson,James T Symanowski,Chandra D Lovejoy,Christopher P Leamon,David E Morgenstern,Richard A Messmann.  (2013-10-16)  PRECEDENT: a randomized phase II trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer..  Journal of clinical oncology : official journal of the American Society of Clinical Oncology,  31  ((35)): (4400-4406).  [PMID:24127448]
60. David W Baker,Jun Zhou,Yi-Ting Tsai,Kaitlen M Patty,Hong Weng,Ewin N Tang,Ashwin Nair,Wen-Jing Hu,Liping Tang.  (2014-04-15)  Development of optical probes for in vivo imaging of polarized macrophages during foreign body reactions..  Acta biomaterialia,  10  ((7)): (2945-2955).  [PMID:24726956]
61. Suhair Sunoqrot,Jason Bugno,Daniel Lantvit,Joanna E Burdette,Seungpyo Hong.  (2014-05-20)  Prolonged blood circulation and enhanced tumor accumulation of folate-targeted dendrimer-polymer hybrid nanoparticles..  Journal of controlled release : official journal of the Controlled Release Society,  191  (115-122).  [PMID:24837188]
62. Juan M Rodriguez,Dante Miranda,Daniel Bunout,Ana María Ronco,María Pía de la Maza,Sandra Hirsch.  (2015-03-25)  Folates Induce Colorectal Carcinoma HT29 Cell Line Proliferation Through Notch1 Signaling..  Nutrition and cancer,  67  ((4)): (706-711).  [PMID:25802929]
63. Gülşah Kaner,Meltem Soylu,Nimet Yüksel,Neriman Inanç,Dilek Ongan,Eda Başmısırlı.  (2015-09-29)  Evaluation of Nutritional Status of Patients with Depression..  BioMed research international,  2015  (521481-521481).  [PMID:26413529]
64. Sungjun Beck,Zhe Zhu,Michelli F Oliveira,Davey M Smith,Jeremy N Rich,Jean A Bernatchez,Jair L Siqueira-Neto.  (2019-04-13)  Mechanism of Action of Methotrexate Against Zika Virus..  Viruses,  11  ((4)):   [PMID:30974762]
65. Dandan Chu,Longfei Li,Yanli Jiang,Jianxin Tan,Jie Ji,Yongli Zhang,Nana Jin,Fei Liu.  (2019-04-27)  Excess Folic Acid Supplementation Before and During Pregnancy and Lactation Activates Fos Gene Expression and Alters Behaviors in Male Mouse Offspring..  Frontiers in neuroscience,  13  (313-313).  [PMID:31024236]
66. B Le,A P T Ngoc,S H Yang.  (2019-12-14)  Synbiotic fermented soymilk with Weissella cibaria FB069 and xylooligosaccharides prevents proliferation in human colon cancer cells..  Journal of applied microbiology,  128  ((5)): (1486-1496).  [PMID:31834648]
67. Ali Razaghi,Antje Maria Zickler,Julian Spallholz,Gilbert Kirsch,Mikael Björnstedt.  (2021-06-26)  Selenofolate inhibits the proliferation of IGROV1 cancer cells independently from folate receptor alpha..  Heliyon,  ((6)): (e07254-e07254).  [PMID:34169173]
68. Qi Yuan,Yunhui Lv,Hao Ding,Qingqing Ke,Caifeng Shi,Jing Luo,Lei Jiang,Junwei Yang,Yang Zhou.  (2021-08-16)  CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair..  Cell death & disease,  12  ((8)): (792-792).  [PMID:34392303]

Solution Calculators