Folic acid - analytical standard,≥98%, high purity , CAS No.59-30-3

78 Citations
Item Number
F103639
Grouped product items
SKUSizeAvailabilityPrice Qty
F103639-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$35.90
F103639-500mg
500mg
In stock
$83.90

Basic Description

Synonymsfolic acid | 59-30-3 | Pteroylglutamic acid | Folate | Vitamin M | Folacin | PteGlu | Folacid | Vitamin B9 | Vitamin Bc | Folicet | Folvite | Incafolic | Folettes | Foliamin | Folipac | Folsan | Millafol | Acifolic | Cytofol | Pteroyl-L-glutamic acid | Folsaure | Folbal | Folsav | Foldine | Vitamin Be | Mi
Specifications & PurityMoligand™, analytical standard, ≥98%
Biochemical and Physiological MechanismsFolic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidyli
Shipped InNormal
Gradeanalytical standard, Moligand™

Associated Targets(Human)

DHFR Tclin Dihydrofolate reductase (3072 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYMS Tclin Thymidylate synthase (1651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC29A1 Tclin Equilibrative nucleoside transporter 1 (1711 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EDNRA Tclin Endothelin receptor ET-A (5008 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FOLR1 Tclin Folate receptor alpha (184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA4 Tclin Neuronal acetylcholine receptor protein alpha-4 subunit (1265 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sus scrofa (849 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a3 Solute carrier organic anion transporter family member 1A3 (65 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cenchrus americanus (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
folC Bifunctional protein FolC (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
INCHI InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChi Key OVBPIULPVIDEAO-LBPRGKRZSA-N
Canonical SMILES C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
Isomeric SMILES C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
RTECS LP5425000
PubChem CID 135398658
Molecular Weight 441.4
Reaxy-Rn 100781

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

7 results found

Lot NumberCertificate TypeDateItem
I2222012Certificate of AnalysisJun 17, 2024 F103639
I2222013Certificate of AnalysisJun 17, 2024 F103639
K2306320Certificate of AnalysisOct 19, 2023 F103639
F2126107Certificate of AnalysisApr 11, 2023 F103639
B2307559Certificate of AnalysisJan 06, 2023 F103639
B2307622Certificate of AnalysisJan 06, 2023 F103639
G1615018Certificate of AnalysisFeb 18, 2022 F103639

Chemical and Physical Properties

SensitivityLight sensitive.
Specific Rotation[α]20° (C=1,NaOH sol.)
Melt Point(°C)250°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

RTECS LP5425000
Reaxy-Rn 100781
Merck Index 4221

Related Documents

Citations of This Product

1. Zhuoran Li, Huikang Yang, Fan Xu, Xuwen Zeng, Haowei Huang, Xinqing Jiang.  (2023)  Folic acid-decorated vitamin E Poly(ethylene glycol) monoplatinum ester with disulfide bond as theranostic nanoparticle for drug resistant tumor diagnosis and treatment.  Materials Research Express,  10  (11): (115404).  [PMID:22159412]
2. Wang Ting, Zhang Jieyuan, Wu Yue, Wang Shiyi, Jiang Xinhui, Zhang Zhengwei, Li Siqiao.  (2023)  Smartphone-integrated ratiometric fluorescence sensing platform based on bimetallic metal–organic framework nanowires for anthrax biomarker detection.  MICROCHIMICA ACTA,  190  (12): (1-9).  [PMID:38006440]
3. Zhaoyun Liu, Xi Wang, Chen Zhang, Kui Lin, Jian Yang, Yi Zhang, Jia Hao, Fei Tian.  (2024)  Folic acid-coupled bovine serum albumin-modified magnetic nanocomposites from quantum-sized Fe3O4 and layered double hydroxide for actively targeted delivery of 5-fluorouracil.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  256  (20): (128385).  [PMID:38000576]
4. Zhanpeng Ren, Jianying Wang, Chenglong Xue, Minghua Deng, Haiyang Yu, Tianci Lin, Jiayuan Zheng, Rongxiang He, Xianbao Wang, Jinhua Li.  (2023)  Ultrahighly Sensitive and Selective Glutathione Sensor Based on Carbon Dot-Functionalized Solution-Gate Graphene Transistor.  ANALYTICAL CHEMISTRY,  95  (48): (17750–17758).  [PMID:37971943]
5. Jiaxin Zhang, Kaicheng Zhou, Jingbo Lin, Xianxian Yao, Dianwen Ju, Xian Zeng, Zhiqing Pang, Wuli Yang.  (2023)  Ferroptosis-enhanced chemotherapy for triple-negative breast cancer with magnetic composite nanoparticles.  BIOMATERIALS,  303  (15): (122395).  [PMID:37988899]
6. Pan Qi, Li Ke, Kang Xueqin, Li Kaixuan, Cheng Zihe, Wang Yafei, Xu Yuye, Li Lei, Li Na, Wu Guilong, Yang Sha, Qi Shuo, Chen Guodong, Tan Xiaofeng, Zhan Yonghua, Tang Li, Zhan Wenhua, Yang Qinglai.  (2023)  Rational design of NIR-II molecule-engineered nanoplatform for preoperative downstaging and imaging-guided surgery of orthotopic hepatic tumor.  JOURNAL OF NANOBIOTECHNOLOGY,  21  (1): (1-17).  [PMID:38111035]
7. Zhu Jun, Yao Yiling, Liao Yuying, Cai Lala, Zhang Wenqi, Hong Nuo, Sun Wenlin, Xiong Chunhua, Yao Lanying.  (2023)  The interaction mechanism between zein and folic acid in alkaline aqueous solutions: an experimental and molecular simulation study.  Food Quality and Safety,    [PMID:]
8. Yingqiao Li, Zhiru Zou, Jinyu An, Xiaoyao Liu, Qian Wu, Junpeng Sun, Xiaobang Liu, Jiaqun Du, Ying Xiong, Chao Wu, Xifan Mei, He Tian.  (2024)  Folic acid-functionalized chitosan nanoparticles with bioenzyme activity for the treatment of spinal cord injury.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,  192  (106667).  [PMID:38061663]
9. Yu Fan, Yangmian Yuan, Mingrui Xiong, Muchuan Jin, Donge Zhang, Dong Yang, Chengyu Liu, Robert B. Petersen, Kun Huang, Anlin Peng, Ling Zheng.  (2023)  Tet1 deficiency exacerbates oxidative stress in acute kidney injury by regulating superoxide dismutase.  Theranostics,  13  (15): ( 5348–5364).  [PMID:37908721]
10. Jun Zhou, Chengyue Zou, Danqun Huo, Chengxiang Chu, Shasha Liu, Mei Yang, Suyi Zhang, Xianfeng Wang, Changjun Hou.  (2023)  Synthesis of N,Si co-doped carbon dots to establish a fluorescent sensor for Hg(II) detection with triple signal output.  Analytical Methods,      [PMID:37767981]
11. Zisan Zeng, Yang Zhao, Luoxing Yang, Fengna Xi, Danke Su.  (2023)  Vertically ordered mesoporous silica film-assisted electrochemical cytosensor for the sensitive detection of HeLa cells.  Frontiers in Chemistry,  11  (1222067).  [PMID:37727833]
12. Qi Zhao, Hui-Hui Mao, Mingyue Xue, Xiao-Zhen Feng, Guo-Cheng Han, Zhencheng Chen, Heinz-Bernhard Kraatz.  (2023)  One-pot synthesis of environmentally-friendly carbon quantum dots for “on-off” rapid fluorescent sensing of folic acid, Fe3+, and Ca2+.  JOURNAL OF LUMINESCENCE,  263  (120091).  [PMID:]
13. Leng Yumin, Qu Panpan, Wang Anyi, Jiang Kai, Dong Yuchen, Han Pei, Cheng Jinbing, Zhang Liwei.  (2023)  Fabrication of glass-based analytical devices by immobilizing nanomaterials on glass substrate with a fluorescent glue for the highly sensitive determination of mercury ions.  MICROCHIMICA ACTA,  190  (8): (1-8).  [PMID:37505293]
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20. Fangling Li, Dongdong Cao, Wenyi Gu, Lin Cui, Zhongpeng Qiu, Zhiyong Liu, Dongmei Li, Xuhong Guo.  (2023)  Delivery of miR-34a-5p by Folic Acid-Modified β-Cyclodextrin-Grafted Polyethylenimine Copolymer Nanocarriers to Resist KSHV.  ACS Applied Nano Materials,  (12): (10826–10836).  [PMID:]
21. Yong-Juan Gu, He-Ya Qian, Fang Zhou, Ling Zhang, Long Chen, Yu Song, Ya-Nan Chen, Hai-Long Zhang.  (2023)  Folic acid relieves bone cancer pain by downregulating P2X2/3 receptors in rats.  BRAIN RESEARCH,  1811  (148405).  [PMID:37164174]
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32. Huang Liyuan, Su Ruobing, Xi Fengna.  (2023)  Sensitive detection of noradrenaline in human whole blood based on Au nanoparticles embedded vertically-ordered silica nanochannels modified pre-activated glassy carbon electrodes.  Frontiers in Chemistry,  11    [PMID:36874060]
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35. Chengwei Yang, Ting Zhang, Jing Zhu, Yunyi Wei, Furong Zhu, Zhong Cheng.  (2023)  Heterologous Expression and Characterization of a Novel Exo-Polygalacturonase from Aspergillus fumigatus Af293 and Its Application in Juice Extraction.  JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY,  33  (4): ( 533–542).  [PMID:36788465]
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Solution Calculators