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Folitixorin (Mixture of Diastereomers) - ≥75%, high purity , CAS No.3432-99-3

  • ≥75%
Item Number
F339657
Grouped product items
SKUSizeAvailabilityPrice Qty
F339657-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$332.90

a folate lyophilized compound suitable for use in the treatment of cancer and other therapies.

Basic Description

SynonymsMFCD19443704 | Q192838 | Sodium chromate (51Cr) (JP17/INN) | 5,10-Methylene-5,6,7,8-tetrahydrofolic acid | N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid | N5,N10-Methylenetetrahydropteroylglutamic Acid
Specifications & Purity≥75%
Storage TempArgon charged,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Application:

A stable folate lyophilized compound suitable for use in the treatment of cancer and other therapies.

Associated Targets(Human)

TYMS Tclin Thymidylate synthase (1651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Enterococcus faecium (13803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lacticaseibacillus casei (578 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

PubMed: [1] , [2] , [3] , [4]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

DailyMed: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

DailyMed: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

DailyMed: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

PubMed: [1] , [2]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

PubMed: [1] , [2] , [3]


Thymidylate synthase antagonistANTAGONISTALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

Other: [1]


PubMed: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

FDA: [1]


PubMed: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

EMA: [1]


Thymidylate synthase inhibitorINHIBITORALA1952Thymidylate synthaseSINGLE PROTEINHomo sapiens

FDA: [1]


Names and Identifiers

IUPAC Name (2S)-2-[[4-(3-amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid
INCHI InChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/t12?,13-/m0/s1
InChi Key QYNUQALWYRSVHF-ABLWVSNPSA-N
Canonical SMILES C1C2CN(CN2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O
Isomeric SMILES C1C2CN(CN2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID 135400185
Molecular Weight 457.44

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
C2327461Certificate of AnalysisNov 23, 2022 F339657
G2230005Certificate of AnalysisJun 17, 2022 F339657
I2410143Certificate of AnalysisJun 17, 2022 F339657

Chemical and Physical Properties

SolubilitySoluble in DMSO.
Sensitivitymoisture sensitive
Melt Point(°C)>220° C

Related Documents

Solution Calculators