Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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F111388-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $101.90 | |
F111388-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $300.90 | |
F111388-500mg | 500mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $700.90 | |
F111388-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,029.90 | |
F111388-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $2,609.90 |
Synonyms | BDBM50021398 | BIDD:ER0119 | NCGC00095207-03 | Spectrum5_000258 | formononetine | KBio1_001263 | BRD-K55567017-001-02-4 | Spectrum4_001429 | SR-01000765510-3 | AB00052676-07 | CCG-38727 | FORMONONETIN (CONSTITUENT OF ASTRAGALUS) | KBio2_005989 | LMPK12050 |
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Specifications & Purity | analytical standard, ≥98% |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Grade | analytical standard |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 7-hydroxy-3-(4-methoxyphenyl)chromen-4-one |
---|---|
INCHI | InChI=1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3 |
InChi Key | HKQYGTCOTHHOMP-UHFFFAOYSA-N |
Canonical SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O |
Isomeric SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O |
WGK Germany | 3 |
RTECS | DJ3100114 |
PubChem CID | 5280378 |
Molecular Weight | 268.26 |
Beilstein | 237979 |
Reaxy-Rn | 237979 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2423023 | Certificate of Analysis | Feb 27, 2024 | F111388 |
A2207519 | Certificate of Analysis | Oct 10, 2023 | F111388 |
A2207520 | Certificate of Analysis | Oct 10, 2023 | F111388 |
A2207649 | Certificate of Analysis | Oct 10, 2023 | F111388 |
H1914185 | Certificate of Analysis | Mar 10, 2023 | F111388 |
C1717027 | Certificate of Analysis | Sep 20, 2022 | F111388 |
K2222475 | Certificate of Analysis | Jun 30, 2022 | F111388 |
Melt Point(°C) | 256-260°C |
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Pictogram(s) | GHS07 |
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Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
WGK Germany | 3 |
RTECS | DJ3100114 |
Reaxy-Rn | 237979 |
Merck Index | 4244 |
1. Lei Qian, Hu Xu, Ruqiang Yuan, Weijing Yun, Yufang Ma. (2024) Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction. BIOMEDICINE & PHARMACOTHERAPY, 170 (116000). [PMID:38070245] |
2. Chun Li, Yuxin Xie, Shaoyu Hu, Hong Yu, Yunke Xu, Hongping Shen, Yuan Yuan, Long Gu, Bangming Pu. (2023) Identification of formononetin as the active compound of CR-SR in hepatocellular carcinoma treatment: An integrated approach combining network pharmacology and weighted gene co-expression networks. Chemical Biology & Drug Design, 103 (1): (e14363). [PMID:37793997] |
3. Yang Jun, Sha Xiaowei, Wu Di, Wu Bo, Pan Xiaohua, Pan Li-Long, Gu Yuanlong, Dong Xiaoliang. (2023) Formononetin alleviates acute pancreatitis by reducing oxidative stress and modulating intestinal barrier. Chinese Medicine, 18 (1): (1-12). [PMID:37370098] |
4. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu. (2023) Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection. JOURNAL OF CHROMATOGRAPHY A, 1704 (464116). [PMID:37290349] |
5. Lijun Zheng, Hongjia Xu, Hanxin Zhang, Caihong Shi, Wei Zhou, Xiangrong Zhang. (2023) Nanostructured lipid carrier as a strategy for encapsulation of formononetin and perilla seed oil: In vitro characterization and stability studies. Food Bioscience, 53 (102707). [PMID:] |
6. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen. (2023) Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach. FOOD CHEMISTRY, 422 (136231). [PMID:37141754] |
7. Boshu Ouyang, Lingling Deng, Fangyong Yang, Hanlin Shi, Na Wang, Weifeng Tang, Xi Huang, Yaolong Zhou, Hang Yu, Ying Wei, Jingcheng Dong. (2023) Albumin-based formononetin nanomedicines for lung injury and fibrosis therapy via blocking macrophage pyroptosis. Materials Today Bio, 20 (100643). [PMID:37214555] |
8. Zili Guo, Yilin Liu, Jiani Xiang, Xianrui Liang. (2023) Mechanochemical preparation of red clover extract/β-cyclodextrin dispersion: Enhanced water solubility and activities in alleviating high-fat diet-induced lipid accumulation and gut microbiota dysbiosis in mice. FOOD CHEMISTRY, 420 (136084). [PMID:37060670] |
9. Jiahui Ji, Lianggong Zhao, Xiaohua Liu, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen, Shilan Feng. (2022) Green synthesis, characterization of formononetin mediated AgNPs and its testing for formothion in typical fruit and vegetable samples. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 112 (104572). [PMID:] |
10. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] |
11. Jiahui Ji, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen, Shilan Feng. (2022) Green synthesis, characterization of Radix Hedysari-mediated silver nanoparticles and their use for sensitive colorimetric detection of Pb2+ in the Yellow River medium. Analytical Methods, 14 (6): (643-651). [PMID:35080529] |
12. Cui Zhanding, Wang Qian, Li Dengliang, Zhao Shihui, Zhang Qian, Tan Yuxin, Gong Qianwen, Liu Ting, Shao Jiang, Zhang Shuang, Huang Hailong, Wang Junzheng, Pei Zhihua, Dong Hao, Wang Kai, Hu Guixue, Li Zhiyong. (2021) Icariin, Formononetin and Caffeic Acid Phenethyl Ester Inhibit Feline Calicivirus Replication In Vitro. ARCHIVES OF VIROLOGY, 166 (9): (2443-2450). [PMID:34173062] |
13. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] |
14. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] |
15. Haifeng Li, Shuang Wang, Fan Cui, Beibei Zhuo, Shuang Wang, Chenrui Zhao, Weilu Liu. (2020) Sensitive and selective detection of puerarin based on the hybrid of reduced graphene oxide and molecularly imprinted polymer. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 185 (113221). [PMID:32145538] |
16. Li-Ting NIU, Gen-Gen LI, Hai-Feng LI, Fan CUI, Jing ZHANG, Ying HUANG, Kai CHEN, Jian-Fu ZHANG, Wen-Fei LI, Wei-Lu LIU. (2019) A Novel Genistein Electrochemical Sensor Based on Molecularly Imprinted Polycarbazole/Carboxylated Multiwalled Carbon Nanotubes Nanocomposite. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 47 (e19095). [PMID:] |
17. Dacheng Wu, Keyan Wu, Qingtian Zhu, Weiming Xiao, Qing Shan, Zhigang Yan, Jian Wu, Bin Deng, Yan Xue, Weijuan Gong, Guotao Lu, Yanbing Ding. (2018) Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway. MEDIATORS OF INFLAMMATION, 2018 (3048532). [PMID:29507526] |
18. Xiafen Xu, Xinhui Li, Xianrui Liang. (2018) Application of ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry in identification of three isoflavone glycosides and their corresponding metabolites. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 32 (3): (262-268). [PMID:29222826] |
19. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |
1. Lei Qian, Hu Xu, Ruqiang Yuan, Weijing Yun, Yufang Ma. (2024) Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction. BIOMEDICINE & PHARMACOTHERAPY, 170 (116000). [PMID:38070245] |
2. Chun Li, Yuxin Xie, Shaoyu Hu, Hong Yu, Yunke Xu, Hongping Shen, Yuan Yuan, Long Gu, Bangming Pu. (2023) Identification of formononetin as the active compound of CR-SR in hepatocellular carcinoma treatment: An integrated approach combining network pharmacology and weighted gene co-expression networks. Chemical Biology & Drug Design, 103 (1): (e14363). [PMID:37793997] |
3. Yang Jun, Sha Xiaowei, Wu Di, Wu Bo, Pan Xiaohua, Pan Li-Long, Gu Yuanlong, Dong Xiaoliang. (2023) Formononetin alleviates acute pancreatitis by reducing oxidative stress and modulating intestinal barrier. Chinese Medicine, 18 (1): (1-12). [PMID:37370098] |
4. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu. (2023) Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection. JOURNAL OF CHROMATOGRAPHY A, 1704 (464116). [PMID:37290349] |
5. Lijun Zheng, Hongjia Xu, Hanxin Zhang, Caihong Shi, Wei Zhou, Xiangrong Zhang. (2023) Nanostructured lipid carrier as a strategy for encapsulation of formononetin and perilla seed oil: In vitro characterization and stability studies. Food Bioscience, 53 (102707). [PMID:] |
6. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen. (2023) Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach. FOOD CHEMISTRY, 422 (136231). [PMID:37141754] |
7. Boshu Ouyang, Lingling Deng, Fangyong Yang, Hanlin Shi, Na Wang, Weifeng Tang, Xi Huang, Yaolong Zhou, Hang Yu, Ying Wei, Jingcheng Dong. (2023) Albumin-based formononetin nanomedicines for lung injury and fibrosis therapy via blocking macrophage pyroptosis. Materials Today Bio, 20 (100643). [PMID:37214555] |
8. Zili Guo, Yilin Liu, Jiani Xiang, Xianrui Liang. (2023) Mechanochemical preparation of red clover extract/β-cyclodextrin dispersion: Enhanced water solubility and activities in alleviating high-fat diet-induced lipid accumulation and gut microbiota dysbiosis in mice. FOOD CHEMISTRY, 420 (136084). [PMID:37060670] |
9. Jiahui Ji, Lianggong Zhao, Xiaohua Liu, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen, Shilan Feng. (2022) Green synthesis, characterization of formononetin mediated AgNPs and its testing for formothion in typical fruit and vegetable samples. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 112 (104572). [PMID:] |
10. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] |
11. Jiahui Ji, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen, Shilan Feng. (2022) Green synthesis, characterization of Radix Hedysari-mediated silver nanoparticles and their use for sensitive colorimetric detection of Pb2+ in the Yellow River medium. Analytical Methods, 14 (6): (643-651). [PMID:35080529] |
12. Cui Zhanding, Wang Qian, Li Dengliang, Zhao Shihui, Zhang Qian, Tan Yuxin, Gong Qianwen, Liu Ting, Shao Jiang, Zhang Shuang, Huang Hailong, Wang Junzheng, Pei Zhihua, Dong Hao, Wang Kai, Hu Guixue, Li Zhiyong. (2021) Icariin, Formononetin and Caffeic Acid Phenethyl Ester Inhibit Feline Calicivirus Replication In Vitro. ARCHIVES OF VIROLOGY, 166 (9): (2443-2450). [PMID:34173062] |
13. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] |
14. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] |
15. Haifeng Li, Shuang Wang, Fan Cui, Beibei Zhuo, Shuang Wang, Chenrui Zhao, Weilu Liu. (2020) Sensitive and selective detection of puerarin based on the hybrid of reduced graphene oxide and molecularly imprinted polymer. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 185 (113221). [PMID:32145538] |
16. Li-Ting NIU, Gen-Gen LI, Hai-Feng LI, Fan CUI, Jing ZHANG, Ying HUANG, Kai CHEN, Jian-Fu ZHANG, Wen-Fei LI, Wei-Lu LIU. (2019) A Novel Genistein Electrochemical Sensor Based on Molecularly Imprinted Polycarbazole/Carboxylated Multiwalled Carbon Nanotubes Nanocomposite. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 47 (e19095). [PMID:] |
17. Dacheng Wu, Keyan Wu, Qingtian Zhu, Weiming Xiao, Qing Shan, Zhigang Yan, Jian Wu, Bin Deng, Yan Xue, Weijuan Gong, Guotao Lu, Yanbing Ding. (2018) Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway. MEDIATORS OF INFLAMMATION, 2018 (3048532). [PMID:29507526] |
18. Xiafen Xu, Xinhui Li, Xianrui Liang. (2018) Application of ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry in identification of three isoflavone glycosides and their corresponding metabolites. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 32 (3): (262-268). [PMID:29222826] |
19. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |