Fostamatinib Disodium Hexahydrate - 98%, high purity , Tyrosine-protein kinase SYK inhibitor, CAS No.914295-16-2, Tyrosine-protein kinase SYK inhibitor

Item Number

F336802

Grouped product items
SKU	Size	Availability	Price
F336802-1mg	1mg	In stock	$22.90
F336802-5mg	5mg	In stock	$94.90
F336802-25mg	25mg	In stock	$261.90
F336802-50mg	50mg	In stock	$426.90
F336802-100mg	100mg	In stock	$699.90

Basic Description

Synonyms	Fostamatinib disodium \| Fostamatinib disodium [USAN] \| Fostamatinib disodium hexahydrate \| R-935788 \| Tamatinib fosdium \| Disulfoton [BSI:ISO] \| R935788 SODIUM HYDRATE \| R-935788 SODIUM HYDRATE \| 86EEZ49YVB \| Fostamatinib disodium (USAN) \| Sodium (6-((5-f
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Tyrosine-protein kinase SYK inhibitor

Associated Targets(Human)

SYK Tclin Tyrosine-protein kinase SYK (7372 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488200699
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488200699
IUPAC Name	disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate;hexahydrate
INCHI	InChI=1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;;;;;;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29);;;61H2/q;2+1;;;;;;/p-2
InChi Key	ZQGJCHHKJNSPMS-UHFFFAOYSA-L
Canonical SMILES	CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
Isomeric SMILES	CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
PubChem CID	24828759
Molecular Weight	732.51

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
D23061548	Certificate of Analysis	Feb 15, 2023	F336802
D23061549	Certificate of Analysis	Feb 15, 2023	F336802
D23061559	Certificate of Analysis	Feb 15, 2023	F336802
D23061560	Certificate of Analysis	Feb 15, 2023	F336802
D23061561	Certificate of Analysis	Feb 15, 2023	F336802
D23061562	Certificate of Analysis	Feb 15, 2023	F336802
D23061563	Certificate of Analysis	Feb 15, 2023	F336802
D23061564	Certificate of Analysis	Feb 15, 2023	F336802
D23061565	Certificate of Analysis	Feb 15, 2023	F336802
D23061566	Certificate of Analysis	Feb 15, 2023	F336802

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice.

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Basic Description