FR 139317 - ≥98%, high purity , CAS No.142375-60-8, Antagonist of ET A receptor

Item Number

F276147

• Synonyms: D-Alanine,N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-1-methyl-D-tryptophyl-3-(2-pyridinyl)- | FR139317 | AKOS024456467 | (R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-pyridin-2-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Highly selective, potent, competitive ET A receptor antagonist (K i values are 1 nM and 7.3 μM for ET A and ET B , respectively). Inhibits endothelin-1-induced vasoconstriction in vivo.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Antagonist of ET A receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.