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G protein-coupled receptors (GPCRs)
Bradykinin receptors
FR173657 , CAS No.F610396, Antagonist of B 2 receptor

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FR173657 , CAS No.F610396, Antagonist of B 2 receptor

Moligand™

PubChem CID: 5311108

Item Number

F610396

Grouped product items
SKU	Size	Availability	Price	Qty
F610396-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
F610396-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

B2 receptor Antagonist

Basic Description

Synonyms	FK-3657 \| 167838-64-4 \| FR-173657 \| FR173657 \| FR 173657 \| 262AL91J0Y \| UNII-262AL91J0Y \| CHEMBL130517 \| (E)-3-(6-acetamidopyridin-3-yl)-N-[2-[2,4-dichloro-N-methyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]prop-2-enamide \| FK 3657 \| (E)-3-((6-Acetamido-3-pyrid
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of B 2 receptor

Associated Targets(Human)

BDKRB2 Tclin B2 bradykinin receptor (5 Activities)

Discover Target: BDKRB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BDKRB2 Tclin Bradykinin B2 receptor (3970 Activities)

Discover Target: BDKRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cavia porcellus (23802 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(E)-3-(6-acetamidopyridin-3-yl)-N-[2-[[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]-methylamino]-2-oxoethyl]prop-2-enamide
INCHI	InChI=1S/C30H27Cl2N5O4/c1-18-7-10-21-5-4-6-25(30(21)35-18)41-17-22-23(31)11-12-24(29(22)32)37(3)28(40)16-34-27(39)14-9-20-8-13-26(33-15-20)36-19(2)38/h4-15H,16-17H2,1-3H3,(H,34,39)(H,33,36,38)/b14-9+
InChi Key	XCKWRUGRUFVXGC-NTEUORMPSA-N
Canonical SMILES	CC(=O)Nc1ccc(cn1)/C=C/C(=O)NCC(=O)N(c1ccc(c(c1Cl)COc1cccc2c1nc(C)cc2)Cl)C
Isomeric SMILES	CC1=NC2=C(C=CC=C2OCC3=C(C=CC(=C3Cl)N(C)C(=O)CNC(=O)/C=C/C4=CN=C(C=C4)NC(=O)C)Cl)C=C1
PubChem CID	5311108

Database links

PubChem CID	5311108
ChEMBL Ligand	CHEMBL130517
BindingDB Ligand	50067301
GPCRdb Ligand	FR173657

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