FTX-6058 - 99%, high purity , CAS No.2490676-18-9

  • ≥99%
Item Number
F649168
Grouped product items
SKUSizeAvailabilityPrice Qty
F649168-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,480.90
F649168-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,450.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsPociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED) . Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including si
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

FTX-6058 is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 can induce HbF protein expression in cell and murine models. FTX-6058 can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia.

In Vitro

FTX-6058 inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Associated Targets(Human)

EED Tchem Polycomb protein EED (645 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Canonical SMILES CC1=C(C=CC=N1)C2=CC3=C(NCC4=C(C=CC5=C4[C@@H](CO5)CO3)F)N6C2=NN=C6
Isomeric SMILES CC1=C(C=CC=N1)C2=CC3=C(NCC4=C(C=CC5=C4[C@@H](CO5)CO3)F)N6C2=NN=C6
PubChem CID 155286052
Molecular Weight 403.41

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 125 mg/mL (309.86 mM; Need ultrasonic)

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Solution Calculators