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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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F649168-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,480.90 | |
F649168-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,450.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | Pociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED) . Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including si |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | FTX-6058 is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 can induce HbF protein expression in cell and murine models. FTX-6058 can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia. In Vitro FTX-6058 inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Canonical SMILES | CC1=C(C=CC=N1)C2=CC3=C(NCC4=C(C=CC5=C4[C@@H](CO5)CO3)F)N6C2=NN=C6 |
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Isomeric SMILES | CC1=C(C=CC=N1)C2=CC3=C(NCC4=C(C=CC5=C4[C@@H](CO5)CO3)F)N6C2=NN=C6 |
PubChem CID | 155286052 |
Molecular Weight | 403.41 |
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Solubility | DMSO : 125 mg/mL (309.86 mM; Need ultrasonic) |
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