| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A424756-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $162.90 |
Inhibitory neurotransmitter
| Synonyms | 4-aminobutyric acid | 4-Aminobutanoic acid | gamma-aminobutyric acid | GABA | 56-12-2 | Piperidic acid | Piperidinic acid | Aminalon | Gaballon | Gammalon | Gammalone | Gammasol | Mielogen | Mielomade | Gamarex | Gammar | butanoic acid, 4-amino- | Reanal | Butyric acid, 4-amino- | gamma-amino |
|---|---|
| Specifications & Purity | Moligand™, 10mM in Water |
| Biochemical and Physiological Mechanisms | Endogenous inhibitory neurotransmitter. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
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| IUPAC Name | 4-aminobutanoic acid |
|---|---|
| INCHI | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
| InChi Key | BTCSSZJGUNDROE-UHFFFAOYSA-N |
| Canonical SMILES | C(CC(=O)O)CN |
| Isomeric SMILES | C(CC(=O)O)CN |
| WGK Germany | 2 |
| RTECS | ES6300000 |
| Alternate CAS | 56-12-2,70582-09-1 (calcium salt (2:1)) |
| PubChem CID | 119 |
| NSC Number | 27418 |
| MeSH Entry Terms | 4 Aminobutanoic Acid;4 Aminobutyric Acid;4-Aminobutanoic Acid;4-Aminobutyric Acid;Acid, Hydrochloride gamma-Aminobutyric;Aminalon;Aminalone;GABA;GABA, Lithium;gamma Aminobutyric Acid;gamma Aminobutyric Acid, Hydrochloride;gamma Aminobutyric Acid, Monolith |
| Molecular Weight | 103.12 |
| Beilstein | 4(3)1316 |
| Reaxy-Rn | 906818 |
Enter Lot Number to search for COA:
| Melt Point(°C) | 195°C |
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| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | ES6300000 |
| Reaxy-Rn | 906818 |
| Merck Index | 430 |
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| 3. Wenting Lin, Kan Li, Yingjun Qin, Xing Han, Xiaohui Chen, Yuan Ren. (2023) Flunitrazepam induces neurotoxicity in zebrafish through microbiota-gut-brain axis. SCIENCE OF THE TOTAL ENVIRONMENT, 901 (165974). [PMID:37532048] [10.1016/j.scitotenv.2023.165974] |
| 4. Xue Yang, Ying Liu, Cai-xia Fu, Ying-Hua Chu, Qun Chen, He Wang, Da-Xiu Wei, Ye-Feng Yao. (2023) Selectively Probing the Magnetic Resonance Signals of γ-Aminobutyric Acid in Human Brains In Vivo. JOURNAL OF MAGNETIC RESONANCE IMAGING, [PMID:37312270] [10.1002/jmri.28853] |
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| 8. Yihan Yu, Dandan Tian, Sanghyok Ri, Tongchol Kim, Kwangjin Ju, Jiongming Zhang, Shuangshuang Teng, Weixia Zhang, Wei Shi, Guangxu Liu. (2023) Gamma-aminobutyric acid (GABA) suppresses hemocyte phagocytosis by binding to GABA receptors and modulating corresponding downstream pathways in blood clam, Tegillarca granosa. FISH & SHELLFISH IMMUNOLOGY, 134 (108608). [PMID:36764632] [10.1016/j.fsi.2023.108608] |
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| 10. Yanni Wu, Shudong He, Tiange Pan, Xinya Miao, Jie Xiang, Yongkang Ye, Xiaodong Cao, Hanju Sun. (2023) Enhancement of γ-aminobutyric acid and relevant metabolites in brown glutinous rice (Oryza sativa L.) through salt stress and low-frequency ultrasound treatments at pre-germination stage. FOOD CHEMISTRY, 410 (135362). [PMID:36608561] [10.1016/j.foodchem.2022.135362] |
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| 36. Mengying Wei, Yuanyuan Liu, Zifeng Pi, Shizhe Li, Mingxin Hu, Yang He, Kexin Yue, Tianshu Liu, Zhiqiang Liu, Fengrui Song, Zhongying Liu. (2019) Systematically Characterize the Anti-Alzheimer’s Disease Mechanism of Lignans from S. chinensis Based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC–Q-TOF-MS. MOLECULES, 24 (7): (1203). [PMID:30934777] [10.3390/molecules24071203] |
| 37. Ni Pengjuan, Xie Junfeng, Chen Chuanxia, Jiang Yuanyuan, Lu Yizhong, Hu Xun. (2019) Fluorometric determination of the activity of alkaline phosphatase and its inhibitors based on ascorbic acid-induced aggregation of carbon dots. MICROCHIMICA ACTA, 186 (3): (1-8). [PMID:30796533] [10.1007/s00604-019-3303-2] |
| 38. Jing Chen, Ying Yuan, Xiaoku Ran, Na Guo, Deqiang Dou. (2018) Metabolomics analysis based on a UPLC-Q-TOF-MS metabolomics approach to compare Lin-Xia-Shan-Shen and garden ginseng. RSC Advances, 8 (53): (30616-30623). [PMID:35546833] [10.1039/C8RA04823A] |
| 39. Wang Xiao-mei, Ren Hao-hao, Yan Yong-gang, Ji Mi-zhi. (2018) A Novel Bio-based Polyaspartic Acid Copolymer: Synthesis, Structure and Performance of Degradation. JOURNAL OF POLYMERS AND THE ENVIRONMENT, 26 (11): (4201-4210). [PMID:] [10.1007/s10924-018-1293-5] |
| 40. Dan Huang, Qing-Song Jiang, Jun-Qing Yang, Ting Cui, Nian-Ru Wang, Ting-Ting Du, Xin-Hui Jiang. (2018) Simultaneous determination of nine analytes related to the pathogenesis of diabetic encephalopathy in diabetic rat cortex and hippocampus by HPLC-FLD. BIOMEDICAL CHROMATOGRAPHY, 32 (11): (e4338). [PMID:30003560] [10.1002/bmc.4338] |
| 41. Ming Wang, Qi-jian Zhang, Zhuang Li, Hua Li, Jian-Mei Lu. (2018) Solvents Effects on Film Morphologies and Memory Behavior of a Perylenediimide-Containing Pendent Polymer. Chemistry-An Asian Journal, 13 (14): (1784-1790). [PMID:29741817] [10.1002/asia.201800331] |
| 42. Ding Shen, Jie Zheng, Xiping Cui, Yingshan Chen, Qiyi He, Rui Lv, Zhaoxia Li, Suqing Zhao. (2018) Analysis of cholyglycine acid as a biomarker for the early diagnosis of liver disease by fluorescence polarization immunoassay. SENSORS AND ACTUATORS B-CHEMICAL, 256 (846). [PMID:] [10.1016/j.snb.2017.10.013] |
| 43. Zhang Qian, Wang Junsong, Liao Shanting, Li Pei, Xu Dingqiao, Lv Yan, Yang Minghua, Kong Lingyi. (2017) Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis. Frontiers in Pharmacology, 8 [PMID:28400733] [10.3389/fphar.2017.00165] |
| 44. Ren Wenkai, Yin Jie, Xiao Hao, Chen Shuai, Liu Gang, Tan Bie, Li Nengzhang, Peng Yuanyi, Li Tiejun, Zeng Benhua, Li Wenxia, Wei Hong, Yin Zhinan, Wu Guoyao, Hardwidge Philip R., Yin Yulong. (2017) Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection. Frontiers in Immunology, 7 (685). [PMID:28138329] [10.3389/fimmu.2016.00685] |
| 45. Lin Luo, Hong-Tao Lei, Jin-Yi Yang, Gong-Liang Liu, Yuan-Ming Sun, Wei-Dong Bai, Hong Wang, Yu-Dong Shen, Sui Chen, Zhen-Lin Xu. (2017) Development of an indirect ELISA for the determination of ethyl carbamate in Chinese rice wine. ANALYTICA CHIMICA ACTA, 950 (162). [PMID:27916121] [10.1016/j.aca.2016.11.008] |
| 46. Kaifei Zhao, Peng Yang, Shichao Du, Kangli Li, Xiaona Li, Zhenfang Li, Yumin Liu, Lanlan Lin, Baohong Hou, Junbo Gong. (2016) Determination and correlation of solubility and thermodynamics of mixing of 4-aminobutyric acid in mono-solvents and binary solvent mixtures. JOURNAL OF CHEMICAL THERMODYNAMICS, 102 (276). [PMID:] [10.1016/j.jct.2016.07.014] |
| 47. Lili Wang, Wencheng Gong, Fang Wang, Zhenya Yu, Zilin Chen. (2016) Efficient bienzyme nanocomposite film for chiral recognition of L-tryptophan, L-phenylalanine and L-tyrosine. Analytical Methods, 8 (17): (3481-3487). [PMID:] [10.1039/C5AY03290C] |
| 48. Wang Fang, Gong Wencheng, Wang Lili, Chen Zilin. (2015) Enhanced amperometric response of a glucose oxidase and horseradish peroxidase based bienzyme glucose biosensor modified with a film of polymerized toluidine blue containing reduced graphene oxide. MICROCHIMICA ACTA, 182 (11): (1949-1956). [PMID:] [10.1007/s00604-015-1535-3] |
| 49. Lihuan Xu, Fang Yang, Chang Su, Lvlv Ji, Cheng Zhang. (2014) Synthesis and properties of novel TEMPO-contained polypyrrole derivatives as the cathode material of organic radical battery. ELECTROCHIMICA ACTA, 130 (148). [PMID:] [10.1016/j.electacta.2014.03.017] |
| 50. Cai F,Xu N,Liu Z,Ding R,Yu S,Dong M,Wang S,Shen J,Tae HS,Adams DJ,Zhang X,Dai Q. (2018) Targeting of N-Type Calcium Channels via GABA-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity.. J Med Chem, 61 (22): (10198-10205). [PMID:30358401] [10.1021/acs.jmedchem.8b01343] |
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| 4. Wenting Lin, Kan Li, Yingjun Qin, Xing Han, Xiaohui Chen, Yuan Ren. (2023) Flunitrazepam induces neurotoxicity in zebrafish through microbiota-gut-brain axis. SCIENCE OF THE TOTAL ENVIRONMENT, 901 (165974). [PMID:37532048] [10.1016/j.scitotenv.2023.165974] |
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| 30. Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu. (2020) Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, [PMID:] [10.1080/10942912.2020.1828455] |
| 31. Yong-hong Liu, Ting-ting Du, Jing-yuan Wan, Hua Zhao, Dan Huang, Jian-sha Li, Xin-hui Jiang. (2020) Simultaneous determination of thirteen substances related to NAFLD in mouse brain tissue using 3-aminobutyric acid as internal standard by HPLC–FLD. BIOMEDICAL CHROMATOGRAPHY, 34 (3): (e4767). [PMID:31785600] [10.1002/bmc.4767] |
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| 33. Wei Xia, Zhu Qingfen, Liu Na, Xu Lihua, Wei Sheng, Fan Zhiyun, Sun Changhua, Zhao Yan, Qiao Mingqi, Wu Jibiao, Hu Defu, Wang Yang, Sun Peng. (2019) Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia. Frontiers in Pharmacology, 10 (1096). [PMID:31611791] [10.3389/fphar.2019.01096] |
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| 35. Xue-Mei Han, Yan-Jie Qin, Ying Zhu, Xin-Lin Zhang, Nan-Xi Wang, Ying Rang, Xue-Jia Zhai, Yong-Ning Lu. (2019) Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 174 (683). [PMID:31288191] [10.1016/j.jpba.2019.06.043] |
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| 39. Jing Chen, Ying Yuan, Xiaoku Ran, Na Guo, Deqiang Dou. (2018) Metabolomics analysis based on a UPLC-Q-TOF-MS metabolomics approach to compare Lin-Xia-Shan-Shen and garden ginseng. RSC Advances, 8 (53): (30616-30623). [PMID:35546833] [10.1039/C8RA04823A] |
| 40. Wang Xiao-mei, Ren Hao-hao, Yan Yong-gang, Ji Mi-zhi. (2018) A Novel Bio-based Polyaspartic Acid Copolymer: Synthesis, Structure and Performance of Degradation. JOURNAL OF POLYMERS AND THE ENVIRONMENT, 26 (11): (4201-4210). [PMID:] [10.1007/s10924-018-1293-5] |
| 41. Dan Huang, Qing-Song Jiang, Jun-Qing Yang, Ting Cui, Nian-Ru Wang, Ting-Ting Du, Xin-Hui Jiang. (2018) Simultaneous determination of nine analytes related to the pathogenesis of diabetic encephalopathy in diabetic rat cortex and hippocampus by HPLC-FLD. BIOMEDICAL CHROMATOGRAPHY, 32 (11): (e4338). [PMID:30003560] [10.1002/bmc.4338] |
| 42. Ming Wang, Qi-jian Zhang, Zhuang Li, Hua Li, Jian-Mei Lu. (2018) Solvents Effects on Film Morphologies and Memory Behavior of a Perylenediimide-Containing Pendent Polymer. Chemistry-An Asian Journal, 13 (14): (1784-1790). [PMID:29741817] [10.1002/asia.201800331] |
| 43. Ding Shen, Jie Zheng, Xiping Cui, Yingshan Chen, Qiyi He, Rui Lv, Zhaoxia Li, Suqing Zhao. (2018) Analysis of cholyglycine acid as a biomarker for the early diagnosis of liver disease by fluorescence polarization immunoassay. SENSORS AND ACTUATORS B-CHEMICAL, 256 (846). [PMID:] [10.1016/j.snb.2017.10.013] |
| 44. Zhang Qian, Wang Junsong, Liao Shanting, Li Pei, Xu Dingqiao, Lv Yan, Yang Minghua, Kong Lingyi. (2017) Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis. Frontiers in Pharmacology, 8 [PMID:28400733] [10.3389/fphar.2017.00165] |
| 45. Ren Wenkai, Yin Jie, Xiao Hao, Chen Shuai, Liu Gang, Tan Bie, Li Nengzhang, Peng Yuanyi, Li Tiejun, Zeng Benhua, Li Wenxia, Wei Hong, Yin Zhinan, Wu Guoyao, Hardwidge Philip R., Yin Yulong. (2017) Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection. Frontiers in Immunology, 7 (685). [PMID:28138329] [10.3389/fimmu.2016.00685] |
| 46. Lin Luo, Hong-Tao Lei, Jin-Yi Yang, Gong-Liang Liu, Yuan-Ming Sun, Wei-Dong Bai, Hong Wang, Yu-Dong Shen, Sui Chen, Zhen-Lin Xu. (2017) Development of an indirect ELISA for the determination of ethyl carbamate in Chinese rice wine. ANALYTICA CHIMICA ACTA, 950 (162). [PMID:27916121] [10.1016/j.aca.2016.11.008] |
| 47. Kaifei Zhao, Peng Yang, Shichao Du, Kangli Li, Xiaona Li, Zhenfang Li, Yumin Liu, Lanlan Lin, Baohong Hou, Junbo Gong. (2016) Determination and correlation of solubility and thermodynamics of mixing of 4-aminobutyric acid in mono-solvents and binary solvent mixtures. JOURNAL OF CHEMICAL THERMODYNAMICS, 102 (276). [PMID:] [10.1016/j.jct.2016.07.014] |
| 48. Lili Wang, Wencheng Gong, Fang Wang, Zhenya Yu, Zilin Chen. (2016) Efficient bienzyme nanocomposite film for chiral recognition of L-tryptophan, L-phenylalanine and L-tyrosine. Analytical Methods, 8 (17): (3481-3487). [PMID:] [10.1039/C5AY03290C] |
| 49. Wang Fang, Gong Wencheng, Wang Lili, Chen Zilin. (2015) Enhanced amperometric response of a glucose oxidase and horseradish peroxidase based bienzyme glucose biosensor modified with a film of polymerized toluidine blue containing reduced graphene oxide. MICROCHIMICA ACTA, 182 (11): (1949-1956). [PMID:] [10.1007/s00604-015-1535-3] |
| 50. Lihuan Xu, Fang Yang, Chang Su, Lvlv Ji, Cheng Zhang. (2014) Synthesis and properties of novel TEMPO-contained polypyrrole derivatives as the cathode material of organic radical battery. ELECTROCHIMICA ACTA, 130 (148). [PMID:] [10.1016/j.electacta.2014.03.017] |
| 51. Cai F,Xu N,Liu Z,Ding R,Yu S,Dong M,Wang S,Shen J,Tae HS,Adams DJ,Zhang X,Dai Q. (2018) Targeting of N-Type Calcium Channels via GABA-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity.. J Med Chem, 61 (22): (10198-10205). [PMID:30358401] [10.1021/acs.jmedchem.8b01343] |
