Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G111443-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $103.90 | |
G111443-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $234.90 | |
G111443-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $842.90 | |
G111443-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,790.90 |
Alkaloid acetylcholinesterase inhibitor
Synonyms | Galanthamine hydrobromide|Galantamine hydrobromide|1953-04-4|Reminyl|Nivalin|Nivaline|Lycoremine hydrobromide|Jilkon hydrobromide|Razadyne|Tamilin|Galanthamine (hydrobromide)|MJ4PTD2VVW|Nivaline (pharmaceutical)|Jilcon hydrobromide|(-)-Galantamine Hydrobr |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Galanthamine hydrobromide prevents β-amyloid-induced apoptosis in SH-SY5Y and |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide |
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INCHI | InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1 |
InChi Key | QORVDGQLPPAFRS-XPSHAMGMSA-N |
Canonical SMILES | CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br |
Isomeric SMILES | CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O.Br |
WGK Germany | 3 |
RTECS | DF8075000 |
PubChem CID | 121587 |
Molecular Weight | 368.27 |
Beilstein | 27(3/4)2184 |
Reaxy-Rn | 3787265 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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A2219724 | Certificate of Analysis | Oct 17, 2023 | G111443 |
F2302722 | Certificate of Analysis | May 22, 2023 | G111443 |
F2302723 | Certificate of Analysis | May 22, 2023 | G111443 |
F2302724 | Certificate of Analysis | May 22, 2023 | G111443 |
F2302725 | Certificate of Analysis | May 22, 2023 | G111443 |
A2219452 | Certificate of Analysis | Jan 04, 2022 | G111443 |
A2219725 | Certificate of Analysis | Jan 04, 2022 | G111443 |
F2218032 | Certificate of Analysis | Jan 04, 2022 | G111443 |
Solubility | insoluble in ETOH; ≥36.9 mg/mL in H2O with gentle warming and ultrasonic; ≥4.60 mg/mL in DMSO |
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Sensitivity | Light Sensitive,Hygroscopic,Heat Sensitive |
Specific Rotation[α] | -95 ° (C=1.4, H2O) |
Melt Point(°C) | 256°C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | DF8075000 |
Reaxy-Rn | 3787265 |
Merck Index | 4340 |