Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Galanthamine hydrobromide prevents β-amyloid-induced apoptosis in SH-SY5Y and
Storage Temp
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
1.Yijing Liao, Xi Mai, Xiaqing Wu, Xing Hu, Xiaoqiao Luo, Guowen Zhang. (2022) Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells. MOLECULES, 27 (22):(7971). [PMID:36432070][10.3390/molecules27227971]
2.Yijing Liao, Xing Hu, Junhui Pan, Guowen Zhang. (2022) Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation. Foods, 11 (2):(168). [PMID:35053900][10.3390/foods11020168]
3.Pei-Pei WANG, Guo-Wei ZHAO, Wen XIA, En-Ji HAN, Lan XIANG. (2014) A new flavonol C-glycoside and a rare bioactive lignanamide from Piper wallichii Miq. Hand.-Mazz. Chinese Journal of Natural Medicines, 12 (377). [PMID:24856762][10.1016/S1875-5364(14)60047-9]
4.Ping Chen, Pei-Pei Wang, Ze-Zhao Jiao, Lan Xiang. (2014) Sesquiterpenoids from the Fruits of Alpinia oxyphylla and Their Anti-Acetylcholinesterase Activity. HELVETICA CHIMICA ACTA, 97 (3):(388-397). [PMID:][10.1002/hlca.201300234]
References
1.Yijing Liao, Xi Mai, Xiaqing Wu, Xing Hu, Xiaoqiao Luo, Guowen Zhang. (2022) Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells. MOLECULES, 27 (22):(7971). [PMID:36432070][10.3390/molecules27227971]
2.Yijing Liao, Xing Hu, Junhui Pan, Guowen Zhang. (2022) Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation. Foods, 11 (2):(168). [PMID:35053900][10.3390/foods11020168]
3.Pei-Pei WANG, Guo-Wei ZHAO, Wen XIA, En-Ji HAN, Lan XIANG. (2014) A new flavonol C-glycoside and a rare bioactive lignanamide from Piper wallichii Miq. Hand.-Mazz. Chinese Journal of Natural Medicines, 12 (377). [PMID:24856762][10.1016/S1875-5364(14)60047-9]
4.Ping Chen, Pei-Pei Wang, Ze-Zhao Jiao, Lan Xiang. (2014) Sesquiterpenoids from the Fruits of Alpinia oxyphylla and Their Anti-Acetylcholinesterase Activity. HELVETICA CHIMICA ACTA, 97 (3):(388-397). [PMID:][10.1002/hlca.201300234]
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