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Galantamine Hydrobromide - 98%, high purity , CAS No.1953-04-4

  • ≥98%
Item Number
G111443
Grouped product items
SKUSizeAvailabilityPrice Qty
G111443-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$103.90
G111443-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$234.90
G111443-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$842.90
G111443-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,790.90

Alkaloid acetylcholinesterase inhibitor

Basic Description

SynonymsGalanthamine hydrobromide|Galantamine hydrobromide|1953-04-4|Reminyl|Nivalin|Nivaline|Lycoremine hydrobromide|Jilkon hydrobromide|Razadyne|Tamilin|Galanthamine (hydrobromide)|MJ4PTD2VVW|Nivaline (pharmaceutical)|Jilcon hydrobromide|(-)-Galantamine Hydrobr
Specifications & Purity≥98%
Biochemical and Physiological MechanismsGalanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Galanthamine hydrobromide prevents β-amyloid-induced apoptosis in SH-SY5Y and
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BCHE Tclin Cholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide
INCHI InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChi Key QORVDGQLPPAFRS-XPSHAMGMSA-N
Canonical SMILES CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br
Isomeric SMILES CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O.Br
WGK Germany 3
RTECS DF8075000
PubChem CID 121587
Molecular Weight 368.27
Beilstein 27(3/4)2184
Reaxy-Rn 3787265

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
A2219724Certificate of AnalysisOct 17, 2023 G111443
F2302722Certificate of AnalysisMay 22, 2023 G111443
F2302723Certificate of AnalysisMay 22, 2023 G111443
F2302724Certificate of AnalysisMay 22, 2023 G111443
F2302725Certificate of AnalysisMay 22, 2023 G111443
A2219452Certificate of AnalysisJan 04, 2022 G111443
A2219725Certificate of AnalysisJan 04, 2022 G111443
F2218032Certificate of AnalysisJan 04, 2022 G111443

Chemical and Physical Properties

Solubilityinsoluble in ETOH; ≥36.9 mg/mL in H2O with gentle warming and ultrasonic; ≥4.60 mg/mL in DMSO
SensitivityLight Sensitive,Hygroscopic,Heat Sensitive
Specific Rotation[α]-95 ° (C=1.4, H2O)
Melt Point(°C)256°C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

WGK Germany 3
RTECS DF8075000
Reaxy-Rn 3787265
Merck Index 4340

Related Documents

Solution Calculators