Gallamine Triethiodide - ≥98%, high purity , Muscle-type nicotinic acetylcholine receptor antagonist, CAS No.65-29-2, Muscle-type nicotinic acetylcholine receptor antagonist

Item Number

G129967

• Synonyms: GALLAMINE TRIETHIODIDE | 65-29-2 | Flaxedil | Benzcurine iodide | Remyolan | Syncurarine | Benzkurin | Pirolakson | Sincurarine | Gallaflex | Parexyl | Pyrolaxon | Relaxan | Retensin | Tricuran | Gallamin triethiodide | Gallamone triethiodide | Gallamoni jodidum | Miowas G | Gallaminii iodidu
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase.Potent and selective M 2 receptor antagonist (K i values are 2.4 and 24 n
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: ALLOSTERIC MODULATOR, ANTAGONIST, CHANNEL BLOCKER
• Mechanism of action: Muscle-type nicotinic acetylcholine receptor antagonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.
Gallamine Triethiodide is a synthetic nondepolarizing blocking drug. Target: mAChR Gallamine triethiodide is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Gallamine triethiodide is commonly used to stabilize muscle contractions during surgical procedures. From Wikipedia.