GANT 61 - ≥98%, high purity , CAS No.500579-04-4

Specifications & Purity: ≥98%

Item Number

G275450

Grouped product items
SKU	Size	Availability	Price
G275450-5mg	5mg	In stock	$64.90
G275450-10mg	10mg	In stock	$103.90
G275450-25mg	25mg	In stock	$234.90
G275450-50mg	50mg	In stock	$391.90
G275450-100mg	100mg	In stock	$705.90
G275450-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,587.90
G275450-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$5,715.90

Discover GANT 61 by Aladdin Scientific in ≥98% for only $64.90. Available - in Ligands at Aladdin Scientific. Selective GLI1 and 2 inhibitor Tags: .

Basic Description

Synonyms	500579-04-4\|GANT61\|GANT 61\|GANT-61\|2,2'-((2-(pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylaniline)\|NSC136476\|2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline\|GNT61\|NSC 13
Specifications & Purity	≥98%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Dry ice

Names and Identifiers

IUPAC Name	2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline
INCHI	InChI=1S/C27H35N5/c1-29(2)25-12-7-5-10-23(25)20-31-18-9-19-32(27(31)22-14-16-28-17-15-22)21-24-11-6-8-13-26(24)30(3)4/h5-8,10-17,27H,9,18-21H2,1-4H3
InChi Key	KVQOGDQTWWCZFX-UHFFFAOYSA-N
Canonical SMILES	CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
Isomeric SMILES	CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
PubChem CID	421610
Molecular Weight	429.61

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7 results found

Lot Number	Certificate Type	Date	Item
A2214479	Certificate of Analysis	Jul 12, 2023	G275450
A2214480	Certificate of Analysis	Jul 12, 2023	G275450
A2214472	Certificate of Analysis	Oct 21, 2022	G275450
A2214473	Certificate of Analysis	Oct 21, 2022	G275450
A2214474	Certificate of Analysis	Oct 21, 2022	G275450
A2214475	Certificate of Analysis	Oct 21, 2022	G275450
A2214476	Certificate of Analysis	Oct 21, 2022	G275450

References

1. Dong H et al.. (2019) GLI1 activation by non-classical pathway integrin avß3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis.. Cell Death Dis, 10 (8): (574). [PMID:31366904]
2. Zhang C et al.. (2016) Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling.. Oncotarget, 7 (52): (86134-86147). [PMID:27863385]
3. Zeng C et al.. (2020) Hedgehog signaling activation required for glypican-6-mediated regulation of invasion, migration, and epithelial-mesenchymal transition of gastric cancer cells.. Biosci Rep, 40 (6): [PMID:32478377]
4. Xu Y et al.. (2014) Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells.. Oncol Rep, 31 (2): (707-12). [PMID:24297612]
5. Qi H et al.. (2019) Inactivation of Nell-1 in Chondrocytes Significantly Impedes Appendicular Skeletogenesis.. J Bone Miner Res, 34 (3): (533-546). [PMID:30352124]
6. Shao JB et al.. (2017) The mechanism of epithelial-mesenchymal transition induced by TGF-ß1 in neuroblastoma cells.. Int J Oncol, 50 (5): (1623-1633). [PMID:28393230]

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Basic Description