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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G118956-1mg | 1mg | In stock | $140.90 | |
G118956-5mg | 5mg | In stock | $565.90 | |
G118956-25mg | 25mg | In stock | $2,547.90 |
Selective CCK2agonist
Synonyms | Little gastrin I | Gastrin I human | Gastrin-17 | Gastrin I (human) | 10047-33-3 | Gastrin 17 | Gastrin heptadecapeptide | Heptadecapeptide gastrin | Little gastrin | 60748-06-3 | G 17 | CHEMBL4451154 | Shg17NS | C97H124N20O31S | GastrinIHuman | Gastrin-1 | Gastrin-I (human) | GASTRINI,HU |
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Specifications & Purity | Moligand™, ≥97%(HPLC) |
Biochemical and Physiological Mechanisms | Endogenous peptide produced in the stomach that acts as a selective CCK2receptor agonist. Stimulates gastric acid secretion. Also used in the culture of stomach organoids. |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of CCK 1 receptor;Agonist of CCK 2 receptor |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Pubchem Sid | 488199064 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488199064 |
IUPAC Name | (4S)-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-[[(2S)-4-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-1-[2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]-5-oxopentanoic acid |
INCHI | InChI=1S/C97H124N20O31S/c1-49(2)39-68(114-95(146)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(148)73-19-12-37-117(73)76(121)48-102-85(136)60-24-30-74(119)104-60)93(144)110-65(29-35-81(130)131)91(142)109-64(28-34-80(128)129)90(141)108-63(27-33-79(126)127)89(140)107-62(26-32-78(124)125)88(139)106-61(25-31-77(122)123)87(138)103-50(3)84(135)113-69(41-52-20-22-55(118)23-21-52)86(137)101-47-75(120)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(145)111-66(36-38-149-4)92(143)115-72(44-82(132)133)96(147)112-67(83(98)134)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100,118H,12,19,24-44,47-48H2,1-4H3,(H2,98,134)(H,101,137)(H,102,136)(H,103,138)(H,104,119)(H,105,120)(H,106,139)(H,107,140)(H,108,141)(H,109,142)(H,110,144)(H,111,145)(H,112,147)(H,113,135)(H,114,146)(H,115,143)(H,116,148)(H,122,123)(H,124,125)(H,126,127)(H,128,129)(H,130,131)(H,132,133)/t50-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-/m0/s1 |
InChi Key | GKDWRERMBNGKCZ-RNXBIMIWSA-N |
Canonical SMILES | CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NCC(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC4=CC=CC=C4)C(=O)N)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C7CCCN7C(=O)CNC(=O)C8CCC(=O)N8 |
Isomeric SMILES | C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NCC(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@@H]7CCCN7C(=O)CNC(=O)[C@@H]8CCC(=O)N8 |
Alternate CAS | 10047-33-3,60748-06-3 |
PubChem CID | 16162108 |
MeSH Entry Terms | G 17;gastrin 17;gastrin heptadecapeptide;gastrin-17;heptadecapeptide gastrin;little gastrin I;SHG17NS |
Molecular Weight | 2098.2 |
PubChem SID | 488199064 |
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Lot Number | Certificate Type | Date | Item |
---|---|---|---|
D23061578 | Certificate of Analysis | Mar 23, 2023 | G118956 |
D23061579 | Certificate of Analysis | Mar 23, 2023 | G118956 |
D23061584 | Certificate of Analysis | Mar 23, 2023 | G118956 |
D23061589 | Certificate of Analysis | Mar 23, 2023 | G118956 |
D23061590 | Certificate of Analysis | Mar 23, 2023 | G118956 |
D23061592 | Certificate of Analysis | Mar 23, 2023 | G118956 |
H2216316 | Certificate of Analysis | Aug 20, 2022 | G118956 |
B2314404 | Certificate of Analysis | Aug 18, 2021 | G118956 |
Solubility | Soluble to 1 (mg/mL) in 1% Ammonia with sonication} |
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Sensitivity | Moisture sensitive;Light sensitive |