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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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G412381-1mg | 1mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,469.90 | |
G412381-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,609.90 | |
G412381-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,719.90 | |
G412381-25mg | 25mg | In stock | $599.90 | |
G412381-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $2,379.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | GATA4-NKX2-5-IN-1 (3i-1000) is a potent, dose-dependent inhibitor of the GATA4–NKX2-5 transcriptional synergy with IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modu |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | GATA4-NKX2-5-IN-1 (3i-1000) is a potent, dose-dependent inhibitor of the GATA4–NKX2-5 transcriptional synergy with IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression. |
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IUPAC Name | N-[4-(diethylamino)phenyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide |
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INCHI | InChI=1S/C21H23N3O2/c1-4-24(5-2)18-13-11-17(12-14-18)22-21(25)19-15(3)26-23-20(19)16-9-7-6-8-10-16/h6-14H,4-5H2,1-3H3,(H,22,25) |
InChi Key | UDDOZWWBHVIGDS-UHFFFAOYSA-N |
Canonical SMILES | CCN(CC)C1=CC=C(C=C1)NC(=O)C2=C(ON=C2C3=CC=CC=C3)C |
Isomeric SMILES | CCN(CC)C1=CC=C(C=C1)NC(=O)C2=C(ON=C2C3=CC=CC=C3)C |
PubChem CID | 753168 |
Molecular Weight | 349.43 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2329125 | Certificate of Analysis | Nov 20, 2023 | G412381 |
K2329128 | Certificate of Analysis | Nov 20, 2023 | G412381 |
K2329210 | Certificate of Analysis | Nov 20, 2023 | G412381 |
K2329211 | Certificate of Analysis | Nov 20, 2023 | G412381 |
K2329212 | Certificate of Analysis | Nov 20, 2023 | G412381 |
K2329214 | Certificate of Analysis | Nov 20, 2023 | G412381 |
Starting at $59.90