Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G274639-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $64.90 | |
G274639-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $146.90 | |
G274639-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $242.90 | |
G274639-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $437.90 | |
G274639-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $984.90 | |
G274639-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,542.90 | |
G274639-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $15,943.90 |
Selective dopamine transport inhibitor
Synonyms | cis-octadecafluorodecahydronaphthalene | G0541 | Vanoxeamine | 1-(2-[bis(4-Fluorophenyl)methoxy]ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride | 67469-78-7 (HCl) | VANOXERINE 2HCL(GBR12909) | GBR-12909 | Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)e |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Potent, selective dopamine reuptake inhibitor (IC 50 = 2.32 µM in rat hippocampal slices; IC 50 = 6-35 µM in whole cell patch clamp recordings). |
Source | Synthetic |
Storage Temp | Store at -20°C,Argon charged,Desiccated |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of DAT;σ2;sigma non-opioid intracellular receptor 1 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. |
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IUPAC Name | 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;dihydrochloride |
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INCHI | InChI=1S/C28H32F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-3,5-6,8-15,28H,4,7,16-22H2;2*1H |
InChi Key | MIBSKSYCRFWIRU-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
Isomeric SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
PubChem CID | 104920 |
Molecular Weight | 523.49 |
PubChem CID | 3455 |
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CAS Registry No. | 67469-78-7 |
ChEMBL Ligand | CHEMBL281594 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2206056 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206057 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206058 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206060 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206061 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206063 | Certificate of Analysis | Oct 20, 2022 | G274639 |
A2206071 | Certificate of Analysis | Oct 20, 2022 | G274639 |
Solubility | Soluble in water to 25 mM (with heating) and in DMSO to 100 mM (with heating) |
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Sensitivity | Hygroscopic |
Melt Point(°C) | 219.0 to 223.0 °C |