GDC046 - 99%, high purity , CAS No.1258292-64-6

Item Number

G412348

• Specifications & Purity: ≥99%
• Biochemical and Physiological Mechanisms: GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

Information

GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor ofTYK2with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively.

Targets

TYK2 (Cell-free assay); JAK2 (Cell-free assay); JAK1 (Cell-free assay); JAK3 (Cell-free assay) 4.8 nM(Ki); 27.6 nM(Ki); 83.8 nM(Ki); 253 nM(Ki)