Gemcitabine hydrochloride - 98%, high purity , DNA polymerase (alpha/delta/epsilon) inhibitor, CAS No.122111-03-9, DNA polymerase (alpha/delta/epsilon) inhibitor

Item Number

G120180

Grouped product items
SKU	Size	Availability	Price
G120180-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
G120180-50mg	50mg	In stock	$11.90
G120180-250mg	250mg	In stock	$13.90
G120180-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$22.90
G120180-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$72.90
G120180-10g	10g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$119.90
G120180-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$199.90

Potent, specific deoxycytidine analog

View related series

Basic Description

Synonyms	GEMCITABINE HYDROCHLORIDE\|122111-03-9\|Gemcitabine HCl\|Gemzar\|LY188011 hydrochloride\|2'-Deoxy-2',2'-difluorocytidine monohydrochloride\|Cytidine, 2'-deoxy-2',2'-difluoro-, monohydrochloride\|LY-188011\|Gemcitabine (Hydrochloride)\|UNII-U347PV74IL\|Gemcitabine (
Specifications & Purity	98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Action Type	INHIBITOR
Mechanism of action	DNA polymerase (alpha/delta/epsilon) inhibitor
Product Description	Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.This product is only used for scientific research.

Names and Identifiers

IUPAC Name	4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride
INCHI	InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
InChi Key	OKKDEIYWILRZIA-OSZBKLCCSA-N
Canonical SMILES	C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
Isomeric SMILES	C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.Cl
WGK Germany	3
RTECS	HA3840000
PubChem CID	60749
Molecular Weight	299.66
Reaxy-Rn	5386970

Certificates

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot Number	Certificate Type	Date	Item
D2415053	Certificate of Analysis	Mar 30, 2024	G120180
D2415054	Certificate of Analysis	Mar 30, 2024	G120180
D2415055	Certificate of Analysis	Mar 30, 2024	G120180
D2415056	Certificate of Analysis	Mar 30, 2024	G120180
D2415057	Certificate of Analysis	Mar 30, 2024	G120180
D2415058	Certificate of Analysis	Mar 30, 2024	G120180
J1811195	Certificate of Analysis	Aug 11, 2022	G120180
J1811194	Certificate of Analysis	Aug 11, 2022	G120180
F2222019	Certificate of Analysis	Jun 01, 2022	G120180
F2222056	Certificate of Analysis	Jun 01, 2022	G120180
F2222060	Certificate of Analysis	Jun 01, 2022	G120180
F2222062	Certificate of Analysis	Jun 01, 2022	G120180
F2222064	Certificate of Analysis	Jun 01, 2022	G120180

Sensitivity

Heat & Light sensitive；Moisture sensitive

Refractive Index

268

Specific Rotation[α]

48°C

Melt Point(°C)

292°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H360:May damage fertility or the unborn child
Precautionary Statements	P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention.
WGK Germany	3
RTECS	HA3840000
Reaxy-Rn	5386970
Merck Index	4386

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description