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Gemifloxacin mesylate - 98% (HPLC), high purity , Topoisomerase IV inhibitor, CAS No.210353-53-0, Topoisomerase IV inhibitor
Basic Description Synonyms GEMIFLOXACIN MESILATE [MART.] | mesilato de gemifloxacina | 2-Methyl-2-phenylpropanamide # | (+/-)-7-(3-(AMINOMETHYL)-4-OXO-1-PYRROLIDINYL)-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID, 7(SUP 4)-(Z)-(O-METHYLOXIME), MONOMET Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synth Storage Temp Protected from light,Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action Topoisomerase IV inhibitor
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488196290 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488196290 IUPAC Name 7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid INCHI InChI=1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+; InChi Key JIYMVSQRGZEYAX-CWUUNJJBSA-N Canonical SMILES CON=C1CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O Isomeric SMILES CO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O PubChem CID 9588170 Molecular Weight 485.49
Chemical and Physical Properties Solubility DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) Sensitivity light &Moisture sensitive.
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B2224412