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Gemifloxacin mesylate - 98% (HPLC), high purity , Topoisomerase IV inhibitor, CAS No.210353-53-0, Topoisomerase IV inhibitor

≥98%(HPLC)

CAS#: 210353-53-0
Formula: C₁₉H₂₄FN₅O₇S
Molecular Weight: 485.49
PubChem CID: 9588170
PubChem SID: 488196290

Item Number

G168525

Grouped product items
SKU	Size	Availability	Price
G168525-5mg	5mg	In stock	$14.90
G168525-25mg	25mg	In stock	$60.90
G168525-100mg	100mg	In stock	$200.90
G168525-250mg	250mg	In stock	$452.90
G168525-1g	1g	In stock	$1,628.90

Basic Description

Synonyms	Gemifloxacin mesylate \| Factive \| 210353-53-0 \| Gemifioxacin Mesylate \| Gemifloxacin mesilate \| Gemifloxacin methanesulfonate \| Floxguard \| Gemixa \| LB 20304a \| LB-20304a \| Gemifloxacin mesylate [USAN] \| Gemifloxacin (mesylate) \| X4S9F8RL01 \| 204519-65-3 \| DTXSID7045948 \| CHEBI:53749 \|
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synth
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Topoisomerase IV inhibitor

Associated Targets(Human)

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)

Discover Target: ABCC2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCB11 Tchem Bile salt export pump (2311 Activities)

Discover Target: ABCB11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)

Discover Target: ABCC3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)

Discover Target: ABCC4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

Discover Target: RUNX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Klebsiella pneumoniae (43867 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Shigella flexneri (1836 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Shigella sp. (79 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Citrobacter (156 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Proteus mirabilis (3894 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Scytonema hofmannii (23 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488196290
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488196290
IUPAC Name	7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
INCHI	InChI=1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+;
InChi Key	JIYMVSQRGZEYAX-CWUUNJJBSA-N
Canonical SMILES	CON=C1CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O
Isomeric SMILES	CO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O
PubChem CID	9588170
Molecular Weight	485.49

Certificates

Certificate of Analysis(COA)

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16 results found

Lot Number	Certificate Type	Date	Item
E2315795	Certificate of Analysis	Mar 17, 2023	G168525
E2315796	Certificate of Analysis	Mar 17, 2023	G168525
E2315798	Certificate of Analysis	Mar 17, 2023	G168525
E2315854	Certificate of Analysis	Mar 17, 2023	G168525
E2315856	Certificate of Analysis	Mar 17, 2023	G168525
E2315857	Certificate of Analysis	Mar 17, 2023	G168525
E2315859	Certificate of Analysis	Mar 17, 2023	G168525
E2315860	Certificate of Analysis	Mar 17, 2023	G168525
E2315863	Certificate of Analysis	Mar 17, 2023	G168525
E2315864	Certificate of Analysis	Mar 17, 2023	G168525
B2224412	Certificate of Analysis	Dec 29, 2021	G168525
B2224418	Certificate of Analysis	Dec 29, 2021	G168525
B2225059	Certificate of Analysis	Dec 29, 2021	G168525
B2225066	Certificate of Analysis	Dec 29, 2021	G168525
B2225091	Certificate of Analysis	Dec 29, 2021	G168525
J2219155	Certificate of Analysis	Dec 29, 2021	G168525

Solubility

DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)

Sensitivity

light &Moisture sensitive.

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