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Genistein - analytical standard,≥98%, high purity , CAS No.446-72-0, Activator of CFTR;Agonist of Estrogen receptor-β;Agonist of Estrogen-related receptor-α;Agonist of Estrogen-related receptor-β;Agonist of Estrogen-related receptor-γ;Agonist of TAS2R14;Agonist of TAS2R39;Activator of TRPC5

  • analytical standard
  • Moligand™
  • ≥98%
Item Number
G106672
Grouped product items
SKUSizeAvailabilityPrice Qty
G106672-20mg
20mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$31.90
G106672-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$686.90
G106672-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,403.90

Basic Description

Synonymsgenistein|446-72-0|Prunetol|4',5,7-Trihydroxyisoflavone|Genisterin|Genisteol|Sophoricol|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one|5,7,4'-Trihydroxyisoflavone|Bonistein|Genestein|Differenol A|NPI 031L|5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopy
Specifications & PurityMoligand™, analytical standard, ≥98%
Biochemical and Physiological Mechanisms

Description:
IC50 Value: 37.5 uM( Topo II) [3]
Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Gradeanalytical standard, Moligand™
Action TypeACTIVATOR, AGONIST
Mechanism of actionActivator of CFTR;Agonist of Estrogen receptor-β;Agonist of Estrogen-related receptor-α;Agonist of Estrogen-related receptor-β;Agonist of Estrogen-related receptor-γ;Agonist of TAS2R14;Agonist of TAS2R39;Activator of TRPC5

Names and Identifiers

IUPAC Name 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
INCHI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
InChi Key TZBJGXHYKVUXJN-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
Isomeric SMILES C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
WGK Germany 3
RTECS NR2392000
PubChem CID 5280961
Molecular Weight 270.24
Beilstein 263823
Reaxy-Rn 263823

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
K1820022Certificate of AnalysisApr 03, 2024 G106672
K2327044Certificate of AnalysisNov 30, 2023 G106672
C2125019Certificate of AnalysisDec 15, 2022 G106672
C2226643Certificate of AnalysisMay 24, 2022 G106672
C2226617Certificate of AnalysisMay 23, 2022 G106672

Chemical and Physical Properties

Melt Point(°C)297-298°C

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS NR2392000
Reaxy-Rn 263823
Merck Index 4391

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