GFB-8438 - 10mM in DMSO, high purity , CAS No.2304549-73-1

Item Number

G422733

• Specifications & Purity: Moligand™, 10mM in DMSO
• Biochemical and Physiological Mechanisms: GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™

Product Description

Information

GFB-8438 GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel .

Targets

hERG channel ; TRPC4 (Cell-free assay); TRPC5 (Cell-free assay) ; 0.18 μM; 0.29 μM