Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G101969-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $31.90 | |
G101969-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $49.90 | |
G101969-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $92.90 |
Platelet -activating factor (PAF) antagonist
Synonyms | Ginkgolide B | Ginkolide B | Ginklide B | 1-Hydroxy-(1beta)-Ginkgolide A | Gingko lactone | 7-Deoxyginkgolide C |
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Specifications & Purity | Moligand™, analytical standard, ≥99% |
Biochemical and Physiological Mechanisms | Primary constituent of Ginkgo biloba. Potential anticancer agent and neuroprotective.Platelet -activating factor (PAF) antagonist (K i = 1.3 μM). A biologically active terpenic lactone. Anti-inflammatory and neuroprotective effects in vivo. Inhibits ather |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | analytical standard, Moligand™ |
Action Type | ANTAGONIST, CHANNEL BLOCKER |
Mechanism of action | Channel blocker of 5-HT 3A;Channel blocker of 5-HT 3AB;Channel blocker of glycine receptor α1 subunit;Channel blocker of glycine receptor α2 subunit;Channel blocker of glycine receptor α3 subunit;Channel blocker of glycine receptor β subunit;Antagonist of |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references |
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IUPAC Name | 8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione |
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INCHI | InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3 |
InChi Key | SQOJOAFXDQDRGF-UHFFFAOYSA-N |
Canonical SMILES | CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O |
Isomeric SMILES | CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O |
WGK Germany | 3 |
PubChem CID | 65243 |
Molecular Weight | 424.4 |
Find and download the COA for your product by matching the lot number on the packaging.
10 results found
Lot Number | Certificate Type | Date | Item |
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E2428441 | Certificate of Analysis | May 15, 2024 | G101969 |
E2428442 | Certificate of Analysis | May 15, 2024 | G101969 |
E2428443 | Certificate of Analysis | May 15, 2024 | G101969 |
E2428444 | Certificate of Analysis | May 15, 2024 | G101969 |
E2428456 | Certificate of Analysis | May 15, 2024 | G101969 |
E2428466 | Certificate of Analysis | May 15, 2024 | G101969 |
K2104225 | Certificate of Analysis | Aug 22, 2023 | G101969 |
K2104235 | Certificate of Analysis | Aug 22, 2023 | G101969 |
K2104242 | Certificate of Analysis | Aug 22, 2023 | G101969 |
L1206005 | Certificate of Analysis | Dec 14, 2022 | G101969 |
Sensitivity | Heat sensitive |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Starting at $59.90
1. Damu Lin, Hongqiang Wu, Zongwei Zhou, Zhenyu Tao, Tanghong Jia, Weiyang Gao. (2021) Ginkgolide B improves multiterritory perforator flap survival by inhibiting endoplasmic reticulum stress and oxidative stress. JOURNAL OF INVESTIGATIVE SURGERY, 34 (6): (610-616). [PMID:31870195] [10.1080/08941939.2019.1676483] |
2. Lingling Wang, Xiuhua Zhao, Fengjian Yang, Weiwei Wu, Yanjie Liu, Li Wang, Lu Wang, Zijian Wang. (2019) Enhanced bioaccessibility in vitro and bioavailability of Ginkgo biloba extract nanoparticles prepared by liquid anti-solvent precipitation. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (6): (2266-2276). [PMID:] [10.1111/ijfs.14141] |
3. Lingling Wang, Xiuhua Zhao, Yuangang Zu, Weiwei Wu, Yuanyuan Li, Chang Zu, Yin Zhang. (2016) Enhanced dissolution rate and oral bioavailability of ginkgo biloba extract by preparing nanoparticles via emulsion solvent evaporation combined with freeze drying (ESE-FR). RSC Advances, 6 (81): (77346-77357). [PMID:] [10.1039/C6RA14771B] |
4. Yuan Gang Zu, Lingling Wang, Xiuhua Zhao, Yuanyuan Li, Weiwei Wu, Chang Zu, Yannian Huang, Mingfang Wu, Ziqi Feng. (2016) Purification of Ginkgo biloba Extract by Antisolvent Recrystallization. CHEMICAL ENGINEERING & TECHNOLOGY, 39 (7): (1301-1308). [PMID:] [10.1002/ceat.201500691] |
1. Damu Lin, Hongqiang Wu, Zongwei Zhou, Zhenyu Tao, Tanghong Jia, Weiyang Gao. (2021) Ginkgolide B improves multiterritory perforator flap survival by inhibiting endoplasmic reticulum stress and oxidative stress. JOURNAL OF INVESTIGATIVE SURGERY, 34 (6): (610-616). [PMID:31870195] [10.1080/08941939.2019.1676483] |
2. Lingling Wang, Xiuhua Zhao, Fengjian Yang, Weiwei Wu, Yanjie Liu, Li Wang, Lu Wang, Zijian Wang. (2019) Enhanced bioaccessibility in vitro and bioavailability of Ginkgo biloba extract nanoparticles prepared by liquid anti-solvent precipitation. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (6): (2266-2276). [PMID:] [10.1111/ijfs.14141] |
3. Lingling Wang, Xiuhua Zhao, Yuangang Zu, Weiwei Wu, Yuanyuan Li, Chang Zu, Yin Zhang. (2016) Enhanced dissolution rate and oral bioavailability of ginkgo biloba extract by preparing nanoparticles via emulsion solvent evaporation combined with freeze drying (ESE-FR). RSC Advances, 6 (81): (77346-77357). [PMID:] [10.1039/C6RA14771B] |
4. Yuan Gang Zu, Lingling Wang, Xiuhua Zhao, Yuanyuan Li, Weiwei Wu, Chang Zu, Yannian Huang, Mingfang Wu, Ziqi Feng. (2016) Purification of Ginkgo biloba Extract by Antisolvent Recrystallization. CHEMICAL ENGINEERING & TECHNOLOGY, 39 (7): (1301-1308). [PMID:] [10.1002/ceat.201500691] |