GITR/CD357 Rat mAb (AF647)

    Application:
  • Flow Cytometry
Features and benefits
  • Host species: Rat
  • Species reactivity(Reacts with): Mouse
  • Isotype: Rat IgG2b
  • Clone Number: DTA-1
  • Conjugation: Alexa Fluor® 647
Item Number
Ab190295
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab190295-10μg (Trial Size)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab190295-25μg
25μg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
Ab190295-100μg
100μg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90

mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (AF647); Flow

Basic Description

Product NameGITR/CD357 Rat mAb (AF647)
SynonymsGitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein |
Specifications & PurityExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL
Biochemical and Physiological MechanismsReceptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Host speciesRat
SpecificityGITR/CD357
ImmunogenMouse CD25+ CD4+ T cells
Positive ControlFlow: C57BL/6 mouse splenocytes.
ConjugationAlexa Fluor® 647
GradeEm:668nm, Ex:650nm, ExactAb™, Validated
Product Description

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow.

Product Properties

IsotypeRat IgG2b
Light Chain Typelambda
Purification MethodProtein G purified
Concentration0.5 mg/mL
Storage TempStore at 2-8°C,Protected from light,Freeze prohibited
Shipped InWet ice
Stability And StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Associated Targets(Human)

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
Flow Cytometry≤0.3μg/test

For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.

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≤0.3μg/test

For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators