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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Ab190295-10μg (Trial Size) Apply for free trial size(?) Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
Ab190295-25μg | 25μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $169.90 | |
Ab190295-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $419.90 |
mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (AF647); Flow
Product Name | GITR/CD357 Rat mAb (AF647) |
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Synonyms | Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein | |
Specifications & Purity | ExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL |
Biochemical and Physiological Mechanisms | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Host species | Rat |
Specificity | GITR/CD357 |
Immunogen | Mouse CD25+ CD4+ T cells |
Positive Control | Flow: C57BL/6 mouse splenocytes. |
Conjugation | Alexa Fluor® 647 |
Grade | Em:668nm, Ex:650nm, ExactAb™, Validated |
Product Description | Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow. |
Isotype | Rat IgG2b |
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Light Chain Type | lambda |
Purification Method | Protein G purified |
Concentration | 0.5 mg/mL |
Storage Temp | Store at 2-8°C,Protected from light,Freeze prohibited |
Shipped In | Wet ice |
Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Application | Dilution info |
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Flow Cytometry | ≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume. ≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume. |
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