Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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G129565-1g | 1g | In stock | $48.90 | |
G129565-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $142.90 |
Potent ATP-dependent K + channel blocker
Synonyms | 3-FORMYLTHIOPHEN-2-YL-2-BORONIC ACID | BRD-K80396088-001-03-9 | AC-23356 | Boronic acid, B-(4-methoxy-2-methylphenyl)- | Gliquidone | Beglynor | SPBio_002972 | 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylure |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Gliquidone is an ATP-dependent K+ (KATP) channel blocker. Gliquidone is an anti-diabetic drug in the sulfonylurea class. Gliquidone is used in the treatment of diabetes mellitus type 2. This block causes a depolarization which leads to activation of volta |
Shipped In | Normal |
Note | 卖完停产,不再备货.Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM. |
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IUPAC Name | 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea |
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INCHI | InChI=1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33) |
InChi Key | LLJFMFZYVVLQKT-UHFFFAOYSA-N |
Canonical SMILES | CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C |
Isomeric SMILES | CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C |
RTECS | DB1584250 |
PubChem CID | 91610 |
Molecular Weight | 527.63 |
Reaxy-Rn | 1559726 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H1518110 | Certificate of Analysis | Mar 15, 2023 | G129565 |
Solubility | Soluble in DMSO (105 mg/ml at 25 °C), water (< 1 mg/ml at 25 °C), and ethanol (6 mg/ml at 25 °C). |
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Melt Point(°C) | 179 °C |
RTECS | DB1584250 |
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Reaxy-Rn | 1559726 |
Merck Index | 4443 |
1. Zixian He, Zhiwei Liu, Haihuan Xie, Pengjie Luo, Xiangmei Li. (2023) An Ultrasensitive Lateral Flow Immunoassay Based on Metal-Organic Framework-Decorated Polydopamine for Multiple Sulfonylureas Adulteration in Functional Foods. Foods, 12 (3): (539). [PMID:36766067] |
1. Zixian He, Zhiwei Liu, Haihuan Xie, Pengjie Luo, Xiangmei Li. (2023) An Ultrasensitive Lateral Flow Immunoassay Based on Metal-Organic Framework-Decorated Polydopamine for Multiple Sulfonylureas Adulteration in Functional Foods. Foods, 12 (3): (539). [PMID:36766067] |