| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| G423487-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
HIF Inhibitors
| Synonyms | 2-Amino-2-Deoxy-D-Glucopyranose | 2-Amino-2-Deoxy-D-Glucopyranoside | 2-Amino-2-Deoxy-D-Glucose | 2-Amino-2-Deoxy-Glucopyranose | 2-Amino-2-Deoxy-Glucopyranoside | 2-Amino-2-Deoxy-Glucose | 2-Deoxy-2-Amino-D-Glucopyranose | 2-Deoxy-2-Amino-D-Glucopyranoside | 2-Deoxy-2-A |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulate |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Glucosamine Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites. |
| pKa | pKₐ: 12.27 (Predicted), pKₐ: 8.44 (Predicted) |
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| Canonical SMILES | C([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)N)O)O)O |
|---|---|
| Isomeric SMILES | C([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)N)O)O)O |
| RTECS | LZ6665000 |
| PubChem CID | 439213 |
| Molecular Weight | 179.17 |
| Beilstein | 1423209 |
Enter Lot Number to search for COA:
| Refractive Index | n20D1.6 (Predicted) |
|---|---|
| Boil Point(°C) | ~449.9° C at 760 mmHg (Predicted) |
| Melt Point(°C) | 109-111° C |
| RTECS | LZ6665000 |
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| 1. Shuwei Yuan, Miaomiao Zhang, Zhen Yao, Jiangyun Liu, Xiang Li, Zhenqing Zhang, Duxin Li. (2024) Isolation, structural characterization, and bioactivities of neutral polysaccharides from Zizania latifolia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 254 (127679). [PMID:37890741] |
| 2. Qihong Jiang, Lin Chen, Rui Wang, Yin Chen, Shanggui Deng, Guoxin Shen, Shulai Liu, Xingwei Xiang. (2024) Hypoglycemic mechanism of Tegillarca granosa polysaccharides on type 2 diabetic mice by altering gut microbiota and regulating the PI3K-akt signaling pathway. Food Science and Human Wellness, 13 (5): (842). [PMID:10025403] |
| 3. Yang Liu, Limei Ran, Yahong Wang, Peng Wan, Hongli Zhou. (2023) Basic characterization, antioxidant and immunomodulatory activities of polysaccharides from sea buckthorn leaves. FITOTERAPIA, 169 (105592). [PMID:37343686] |
| 4. Shuwei Yuan, Jiahui Wang, Xiang Li, Xun Zhu, Zhenqing Zhang, Duxin Li. (2023) Study on the structure, antioxidant activity and degradation pattern of polysaccharides isolated from lotus seedpod. CARBOHYDRATE POLYMERS, 316 (121065). [PMID:37321745] |
| 5. Cui Cao, Lilong Wang, Xueqian Zhang, Chunqing Ai, Zhongfu Wang, Linjuan Huang, Shuang Song, Beiwei Zhu. (2023) Interaction between Bacteroidetes species in the fermentation of Lycium barbarum arabinogalactan. FOOD CHEMISTRY, 409 (135288). [PMID:36584527] |
| 6. Zhengyu Hu, Jiaming Wang, Long Jin, Tieqiang Zong, Yuanqi Duan, Jinfeng Sun, Wei Zhou, Gao Li. (2022) Preparation, Characterization and Anti-Complementary Activity of Three Novel Polysaccharides from Cordyceps militaris. Polymers, 14 (21): (4636). [PMID:36365633] |
| 7. Dongxue Cao, Enwei Wei, Zeyu Wang, Zhengyu Hu, Ling Qi, Hongli Zhou, Jingli Zhao. (2022) Microwave-assisted extraction, structural elucidation, and in vitro anti-glioma and immunostimulatory activity of polysaccharide from Panax ginseng C. A. Meyer. INDUSTRIAL CROPS AND PRODUCTS, 189 (115729). [PMID:] |
| 8. Jinfang Zhang, Baoyue Zhu, Xiaojian Xu, Yihan Liu, Qinggang Li, Yu Li, Fuping Lu. (2022) Remodeling Bacillus amyloliquefaciens Cell Wall Rigidity to Reduce Cell Lysis and Increase the Yield of Heterologous Proteins. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (34): (10552–10562). [PMID:35984403] |
| 9. Zhengyu Hu, Ruiying Yu, Jinfeng Sun, Yuanqi Duan, Hongli Zhou, Wei Zhou, Gao Li. (2022) Static decolorization of polysaccharides from the leaves of Rhododendron dauricum: Process optimization, characterization and antioxidant activities. PROCESS BIOCHEMISTRY, 121 (113). [PMID:] |
| 10. Lei Li, Yun Fang, Yongmei Xia, Chunling Bo, Ye Fan. (2022) Monosaccharides driving the formation of conjugated linoleic acid vesicles in near-neutral solutions via weak noncovalent bonding interactions. JOURNAL OF MOLECULAR LIQUIDS, 351 (118656). [PMID:] |
| 11. Hualing Xie, Jingyu Fang, Mohamed A. Farag, Zhenhao Li, Peilong Sun, Ping Shao. (2022) Dendrobium officinale leaf polysaccharides regulation of immune response and gut microbiota composition in cyclophosphamide-treated mice. Food Chemistry-X, 13 (100235). [PMID:35499019] |
| 1. Shuwei Yuan, Miaomiao Zhang, Zhen Yao, Jiangyun Liu, Xiang Li, Zhenqing Zhang, Duxin Li. (2024) Isolation, structural characterization, and bioactivities of neutral polysaccharides from Zizania latifolia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 254 (127679). [PMID:37890741] |
| 2. Qihong Jiang, Lin Chen, Rui Wang, Yin Chen, Shanggui Deng, Guoxin Shen, Shulai Liu, Xingwei Xiang. (2024) Hypoglycemic mechanism of Tegillarca granosa polysaccharides on type 2 diabetic mice by altering gut microbiota and regulating the PI3K-akt signaling pathway. Food Science and Human Wellness, 13 (5): (842). [PMID:10025403] |
| 3. Yang Liu, Limei Ran, Yahong Wang, Peng Wan, Hongli Zhou. (2023) Basic characterization, antioxidant and immunomodulatory activities of polysaccharides from sea buckthorn leaves. FITOTERAPIA, 169 (105592). [PMID:37343686] |
| 4. Shuwei Yuan, Jiahui Wang, Xiang Li, Xun Zhu, Zhenqing Zhang, Duxin Li. (2023) Study on the structure, antioxidant activity and degradation pattern of polysaccharides isolated from lotus seedpod. CARBOHYDRATE POLYMERS, 316 (121065). [PMID:37321745] |
| 5. Cui Cao, Lilong Wang, Xueqian Zhang, Chunqing Ai, Zhongfu Wang, Linjuan Huang, Shuang Song, Beiwei Zhu. (2023) Interaction between Bacteroidetes species in the fermentation of Lycium barbarum arabinogalactan. FOOD CHEMISTRY, 409 (135288). [PMID:36584527] |
| 6. Zhengyu Hu, Jiaming Wang, Long Jin, Tieqiang Zong, Yuanqi Duan, Jinfeng Sun, Wei Zhou, Gao Li. (2022) Preparation, Characterization and Anti-Complementary Activity of Three Novel Polysaccharides from Cordyceps militaris. Polymers, 14 (21): (4636). [PMID:36365633] |
| 7. Dongxue Cao, Enwei Wei, Zeyu Wang, Zhengyu Hu, Ling Qi, Hongli Zhou, Jingli Zhao. (2022) Microwave-assisted extraction, structural elucidation, and in vitro anti-glioma and immunostimulatory activity of polysaccharide from Panax ginseng C. A. Meyer. INDUSTRIAL CROPS AND PRODUCTS, 189 (115729). [PMID:] |
| 8. Jinfang Zhang, Baoyue Zhu, Xiaojian Xu, Yihan Liu, Qinggang Li, Yu Li, Fuping Lu. (2022) Remodeling Bacillus amyloliquefaciens Cell Wall Rigidity to Reduce Cell Lysis and Increase the Yield of Heterologous Proteins. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (34): (10552–10562). [PMID:35984403] |
| 9. Zhengyu Hu, Ruiying Yu, Jinfeng Sun, Yuanqi Duan, Hongli Zhou, Wei Zhou, Gao Li. (2022) Static decolorization of polysaccharides from the leaves of Rhododendron dauricum: Process optimization, characterization and antioxidant activities. PROCESS BIOCHEMISTRY, 121 (113). [PMID:] |
| 10. Lei Li, Yun Fang, Yongmei Xia, Chunling Bo, Ye Fan. (2022) Monosaccharides driving the formation of conjugated linoleic acid vesicles in near-neutral solutions via weak noncovalent bonding interactions. JOURNAL OF MOLECULAR LIQUIDS, 351 (118656). [PMID:] |
| 11. Hualing Xie, Jingyu Fang, Mohamed A. Farag, Zhenhao Li, Peilong Sun, Ping Shao. (2022) Dendrobium officinale leaf polysaccharides regulation of immune response and gut microbiota composition in cyclophosphamide-treated mice. Food Chemistry-X, 13 (100235). [PMID:35499019] |
