Grouped product items

SKU

Size

Availability

Price

Qty

G121372-25mg

25mg

In stock

$61.90

G121372-100mg

100mg

Available within 4-8 weeks(?)

$179.90

G121372-500mg

500mg

In stock

$807.90

Basic Description

Synonyms	Glutathione monoethyl ester \| 118421-50-4 \| 92614-59-0 \| Glutathione reduced ethyl ester \| N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine monoethyl ester \| GSH-OEt \| GSH-MEE \| (2S)-2-amino-5-[[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopenta
Specifications & Purity	≥90%
Biochemical and Physiological Mechanisms	Glutathione reduced ethyl ester is cell permeable and has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. Glutathione reduced ethyl ester is a derivative of GSH that may be used to partiall
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

PAM Tchem Peptidyl-glycine alpha-amidating monooxygenase (0 Activities)

Discover Target: PAM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PAM Tchem Peptidyl-glycine alpha-amidating monooxygenase (90 Activities)

Discover Target: PAM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(2S)-2-amino-5-[[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
INCHI	InChI=1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
InChi Key	JKRODHBGNBKZLE-YUMQZZPRSA-N
Canonical SMILES	CCOC(=O)CNC(=O)C(CS)NC(=O)CCC(C(=O)O)N
Isomeric SMILES	CCOC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@@H](C(=O)O)N
WGK Germany	3
PubChem CID	147253
Molecular Weight	335.38

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
G2411570	Certificate of Analysis	Jun 21, 2024	G121372
G2411576	Certificate of Analysis	Jun 21, 2024	G121372
G2411591	Certificate of Analysis	Jun 21, 2024	G121372
G2411592	Certificate of Analysis	Jun 21, 2024	G121372
G2222333	Certificate of Analysis	Jun 07, 2022	G121372
G2222337	Certificate of Analysis	Jun 07, 2022	G121372
G2222341	Certificate of Analysis	Jun 07, 2022	G121372
H2330033	Certificate of Analysis	Jun 07, 2022	G121372
K2201575	Certificate of Analysis	Jun 07, 2022	G121372

Safety and Hazards(GHS)

WGK Germany	3

Citations of This Product

1. Yufen Liao, Xin Wang, Guangyun Ran, Shiyu Zhang, Chutian Wu, Rong Tan, Ying Liu, Yan He, Ting Liu, Zhongxiu Wu, Ying Peng, Weiwei Li, Jiang Zheng. (2023) DNA damage and up-regulation of PARP-1 induced by columbin in vitro and in vivo. TOXICOLOGY LETTERS, 379 (20). [PMID:36905973]
2. Shiyu Zhang, Ying Liu, Ting Liu, Jie Pan, Rong Tan, Zixia Hu, Bowen Gong, Yufen Liao, Peng Luo, Qibing Zeng, Weiwei Li, Jiang Zheng. (2022) DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo. TOXICOLOGY AND APPLIED PHARMACOLOGY, 443 (116007). [PMID:35367474]
3. Xianya Qin, Conglian Yang, Hongbo Xu, Runzan Zhang, Dan Zhang, Jingyao Tu, Yuanyuan Guo, Boning Niu, Li Kong, Zhiping Zhang. (2021) Cell-Derived Biogenetic Gold Nanoparticles for Sensitizing Radiotherapy and Boosting Immune Response against Cancer. Small, 17 (50): (2103984). [PMID:34723421]

References

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18. Xianxian Wu,Boram Lee,Lingxiang Zhu,Zhi Ding,Yin Chen. (2020-04-23) Exposure to mold proteases stimulates mucin production in airway epithelial cells through Ras/Raf1/ERK signal pathway.. PloS one, 15 ((4)): (e0231990-e0231990). [PMID:32320453]
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32. Yufen Liao, Xin Wang, Guangyun Ran, Shiyu Zhang, Chutian Wu, Rong Tan, Ying Liu, Yan He, Ting Liu, Zhongxiu Wu, Ying Peng, Weiwei Li, Jiang Zheng. (2023) DNA damage and up-regulation of PARP-1 induced by columbin in vitro and in vivo. TOXICOLOGY LETTERS, 379 (20). [PMID:36905973]
33. Shiyu Zhang, Ying Liu, Ting Liu, Jie Pan, Rong Tan, Zixia Hu, Bowen Gong, Yufen Liao, Peng Luo, Qibing Zeng, Weiwei Li, Jiang Zheng. (2022) DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo. TOXICOLOGY AND APPLIED PHARMACOLOGY, 443 (116007). [PMID:35367474]
34. Xianya Qin, Conglian Yang, Hongbo Xu, Runzan Zhang, Dan Zhang, Jingyao Tu, Yuanyuan Guo, Boning Niu, Li Kong, Zhiping Zhang. (2021) Cell-Derived Biogenetic Gold Nanoparticles for Sensitizing Radiotherapy and Boosting Immune Response against Cancer. Small, 17 (50): (2103984). [PMID:34723421]

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Glutathione reduced ethyl ester - 90%, high purity , CAS No.92614-59-0