Gly-Arg-Gly-Asp-Ser TFA - ≥98%, high purity , CAS No.96426-21-0

  • ≥98%
Item Number
G305036
Grouped product items
SKUSizeAvailabilityPrice Qty
G305036-5mg
5mg
In stock
$105.90
G305036-10mg
10mg
In stock
$165.90
G305036-25mg
25mg
In stock
$260.90
G305036-50mg
50mg
In stock
$469.90

Synthetic integrin antagonist

Basic Description

SynonymsL-Serine, N-(N-(N-(N2-glycyl-L-arginyl)glycyl)-L-alpha-aspartyl)- | Gly-Arg-Gly-Asp-Ser, >=97% (HPLC) | NH2-Gly-Arg-Gly-Asp-Ser | (6S,12S,15S)-1-amino-6-(2-aminoacetamido)-12-(carboxymethyl)-15-(hydroxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexa
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSynthetic integrin antagonist. Contains the RGD (Arg-Gly-Asp) sequence found in many extracellular matrix adhesive proteins.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

ITGA2B Tclin Integrin alpha-IIb (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA4 Tclin Integrin alpha-4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB3 Tclin Integrin beta-3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB1 Tclin Integrin beta-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB3 Tclin Integrin alpha-V/beta-3 (2708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB1 Tclin Integrin alpha-4/beta-1 (2269 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-IIb/beta-3 (3481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (3S)-3-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-oxobutanoic acid
INCHI InChI=1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
InChi Key RGNVSYKVCGAEHK-GUBZILKMSA-N
Canonical SMILES C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)CN)CN=C(N)N
Isomeric SMILES C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)CN)CN=C(N)N
PubChem CID 123811
Molecular Weight 490.47(free base)

Certificates

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4 results found

Lot NumberCertificate TypeDateItem
C2303262Certificate of AnalysisSep 27, 2022 G305036
C2303263Certificate of AnalysisSep 27, 2022 G305036
C2303264Certificate of AnalysisSep 27, 2022 G305036
C2303265Certificate of AnalysisSep 27, 2022 G305036

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