Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infec
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Product Description
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease
In Vitro
Glycolithocholic acid 3-sulfate (100 μg/mL) protects MT-4 cells against HIV-1-induced cytopathogenicity. Glycolithocholic acid 3-sulfate (200 μg/mL) shows no toxicity for host cells. Glycolithocholic acid 3-sulfate inhibits HIV-1 antigen expression in HIV-1-infected CEM cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Glycolithocholic acid 3-sulfate (24 μmoL /100 g; i.v., once) induces intrahepatic cholestasis and increases biliary cholesterol secretion in male Wistar rats with bile fistula. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats with bile fistulaDosage: 24 μmoL/100 g Administration: Intravenous injection; 24 μmoL/100 g Result: Induced intrahepatic cholestasis and increased biliary cholesterol secretion.
Form:Solid
IC50& Target:Microbial Metabolite
Associated Targets(Human)
ABCC4TchemMultidrug resistance-associated protein 4 (785 Activities)
