Glycyrrhizic acid - analytical standard, high purity , CAS No.1405-86-3, Inhibitor of OATP1B1;Inhibitor of OATP1B3

Item Number
G111375
Grouped product items
SKUSizeAvailabilityPrice Qty
G111375-20mg
20mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$28.90

Basic Description

Synonyms(3.BETA.,20.BETA.)-20-CARBOXY-11-OXO-30-NOROLEAN-12-EN-3-YL 2-O-.BETA.-D-GLUCOPYRANURONOSYL-.ALPHA.-D-GLUCOPYRANOSIDURONIC ACID | CCRIS 8444 | Glycyrrhetinic acid glycoside | LPLVUJXQOOQHMX-QWBHMCJMSA-N | MFCD00065194 | 18.beta.-glycyrrhizic acid | Glycyr
Specifications & PurityMoligand™, analytical standard
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Gradeanalytical standard, Moligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of OATP1B1;Inhibitor of OATP1B3
Product Description

Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.

Associated Targets(Human)

HSD11B2 Tchem Corticosteroid 11-beta-dehydrogenase isozyme 2 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HSD11B1 Tclin Corticosteroid 11-beta-dehydrogenase isozyme 1 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
blaZ Beta-lactamase (285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hsd11b1 11-beta-hydroxysteroid dehydrogenase 1 (202 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gusb Beta-glucuronidase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hsd11b2 11-beta-hydroxysteroid dehydrogenase 2 (82 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human gammaherpesvirus 4 (1538 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Influenza A virus (11224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PYGM Glycogen phosphorylase, muscle form (1331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dengue virus type 2 (2400 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a1 Solute carrier organic anion transporter family member 1A1 (265 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a4 Solute carrier organic anion transporter family member 1A4 (114 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1b2 Solute carrier organic anion transporter family member 1B2 (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slco1a5 Solute carrier organic anion transporter family member 1A5 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV (424 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
INCHI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
InChi Key LPLVUJXQOOQHMX-QWBHMCJMSA-N
Canonical SMILES CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C
Isomeric SMILES C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O
PubChem CID 14982
Molecular Weight 822.93

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
H2423256Certificate of AnalysisAug 31, 2024 G111375
A2425296Certificate of AnalysisFeb 04, 2024 G111375
A2425306Certificate of AnalysisFeb 04, 2024 G111375
F2305266Certificate of AnalysisJun 13, 2023 G111375
L2201716Certificate of AnalysisOct 31, 2022 G111375
G2222273Certificate of AnalysisJul 29, 2022 G111375

Chemical and Physical Properties

SensitivityMoisture sensitive
Specific Rotation[α]61 ° (C=1.5, EtOH)

Safety and Hazards(GHS)

Merck Index 4505

Related Documents

Citations of This Product

1. Yang Liu, Zhenfeng Wu, Yingchong Chen, Yongmei Guan, Huiwen Guo, Ming Yang, Pengfei Yue.  (2023)  Rubusoside As a Multifunctional Stabilizer for Novel Nanocrystal-Based Solid Dispersions with a High Drug Loading: A Case Study.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:37659720] [10.1016/j.xphs.2023.08.024]
2. Zongjian Sun, Mingxin Zhang, Yanjun Wei, Mengshuang Li, Xianggen Wu, Meng Xin.  (2023)  A simple but novel glycymicelle ophthalmic solution based on two approved drugs empagliflozin and glycyrrhizin: in vitro/in vivo experimental evaluation for the treatment of corneal alkali burns.  Biomaterials Science,  11  (7): (2531-2542).  [PMID:36779571] [10.1039/D2BM01957D]
3. Chenxi Wang, Ruyu Yan, Xiaojing Li, Shangyuan Sang, David Julian McClements, Long Chen, Jie Long, Aiquan Jiao, Jinpeng Wang, Chao Qiu, Zhengyu Jin.  (2023)  Development of emulsion-based edible inks for 3D printing applications: Pickering emulsion gels.  FOOD HYDROCOLLOIDS,  138  (108482).  [PMID:] [10.1016/j.foodhyd.2023.108482]
4. Jun Zheng, Xianwen Song, Zhaoyu Yang, Yun Tan, Chao Yin, Jiafu Yin, Yufang Lu, Yufan Yang, Chuntai Liu, Lunzhao Yi, Yi Zhang.  (2023)  Self-assembling glycyrrhizic acid micellar hydrogels as encapsulant carriers for delivery of curcumin.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  658  (130680).  [PMID:] [10.1016/j.colsurfa.2022.130680]
5. Qiaoyu He, Yumeng Shi, Hong Xing, Qian Tang, Jing Liu, Chunxia Li, Han Zhang, Boli Zhang, Junhua Zhang, Xiaopeng Chen.  (2022)  Modulating effect of Xuanfei Baidu granule on host metabolism and gut microbiome in rats..  Frontiers in Pharmacology,  13  (922642-922642).  [PMID:36147334] [10.3389/fphar.2022.922642]
6. Yujie Zhang, Min Chen, Shouyong Zhou, Haifeng Han, Mingliang Zhang, Hongdeng Qiu.  (2022)  A carbonylative coupling approach to alkyl stationary phases with variable embedded carbamate groups for high-performance liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,  1661  (462718).  [PMID:34875517] [10.1016/j.chroma.2021.462718]
7. Zhaoyan Zhao, Yuchen Xiao, Lingqing Xu, Ye Liu, Guanmin Jiang, Wei Wang, Bin Li, Tianchuan Zhu, Qingqin Tan, Lantian Tang, Haibo Zhou, Xi Huang, Hong Shan.  (2021)  Glycyrrhizic Acid Nanoparticles as Antiviral and Anti-inflammatory Agents for COVID-19 Treatment.  ACS Applied Materials & Interfaces,  13  (18): (20995–21006).  [PMID:33930273] [10.1021/acsami.1c02755]
8. Ting Pan, Yali Lin, Quanzhou Wu, Kaiwen Huang, Jianfeng He.  (2020)  Preparation of boronate-functionalized surface molecularly imprinted polymer microspheres with polydopamine coating for specific recognition and separation of glycoside template.  JOURNAL OF SEPARATION SCIENCE,  44  (12): (2465-2473).  [PMID:32367689] [10.1002/jssc.202000125]
9. Ting Tong, Hongwei Hu, Junwei Zhou, Shuangfei Deng, Xiaotong Zhang, Wantao Tang, Liurong Fang, Shaobo Xiao, Jiangong Liang.  (2020)  Glycyrrhizic-Acid-Based Carbon Dots with High Antiviral Activity by Multisite Inhibition Mechanisms.  Small,  16  (13): (1906206).  [PMID:32077621] [10.1002/smll.201906206]
10. Qiu Miao, Huang Keqing, Liu Yanzhuo, Yang Yuqing, Tang Honglin, Liu Xiaoxiao, Wang Chenlong, Chen Honglei, Xiong Yu, Zhang Jing, Yang Jing.  (2019)  Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis.  Mucosal Immunology,  12  (4): (945-957).  [PMID:30755716] [10.1038/s41385-019-0144-6]
11. Haixia Li, Dandan Guo, Liangran Zhang, Xiao Feng.  (2018)  Glycyrrhizin attenuates histamine-mediated MUC5AC upregulation, inflammatory cytokine production, and aquaporin 5 downregulation through suppressing the NF-κB pathway in human nasal epithelial cells.  CHEMICO-BIOLOGICAL INTERACTIONS,  285  (21).  [PMID:29452068] [10.1016/j.cbi.2018.02.010]
12. Zhen-Huan Lv, Trinh Anh Phuong, Shi-Jie Jin, Xiao-Xue Li, Ming Xu.  (2017)  Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes.  Oncotarget,  (53): ( 91291–91305).  [PMID:29207644] [10.18632/oncotarget.20443]
13. Huang Run-Yue, Chu Yong-Liang, Jiang Ze-Bo, Chen Xiu-Ming, Zhang Xian, Zeng Xing.  (2014)  Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY,  33  (2): (375-388).  [PMID:24556579] [10.1159/000356677]

References

1. Yang Liu, Zhenfeng Wu, Yingchong Chen, Yongmei Guan, Huiwen Guo, Ming Yang, Pengfei Yue.  (2023)  Rubusoside As a Multifunctional Stabilizer for Novel Nanocrystal-Based Solid Dispersions with a High Drug Loading: A Case Study.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:37659720] [10.1016/j.xphs.2023.08.024]
2. Zongjian Sun, Mingxin Zhang, Yanjun Wei, Mengshuang Li, Xianggen Wu, Meng Xin.  (2023)  A simple but novel glycymicelle ophthalmic solution based on two approved drugs empagliflozin and glycyrrhizin: in vitro/in vivo experimental evaluation for the treatment of corneal alkali burns.  Biomaterials Science,  11  (7): (2531-2542).  [PMID:36779571] [10.1039/D2BM01957D]
3. Chenxi Wang, Ruyu Yan, Xiaojing Li, Shangyuan Sang, David Julian McClements, Long Chen, Jie Long, Aiquan Jiao, Jinpeng Wang, Chao Qiu, Zhengyu Jin.  (2023)  Development of emulsion-based edible inks for 3D printing applications: Pickering emulsion gels.  FOOD HYDROCOLLOIDS,  138  (108482).  [PMID:] [10.1016/j.foodhyd.2023.108482]
4. Jun Zheng, Xianwen Song, Zhaoyu Yang, Yun Tan, Chao Yin, Jiafu Yin, Yufang Lu, Yufan Yang, Chuntai Liu, Lunzhao Yi, Yi Zhang.  (2023)  Self-assembling glycyrrhizic acid micellar hydrogels as encapsulant carriers for delivery of curcumin.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  658  (130680).  [PMID:] [10.1016/j.colsurfa.2022.130680]
5. Qiaoyu He, Yumeng Shi, Hong Xing, Qian Tang, Jing Liu, Chunxia Li, Han Zhang, Boli Zhang, Junhua Zhang, Xiaopeng Chen.  (2022)  Modulating effect of Xuanfei Baidu granule on host metabolism and gut microbiome in rats..  Frontiers in Pharmacology,  13  (922642-922642).  [PMID:36147334] [10.3389/fphar.2022.922642]
6. Yujie Zhang, Min Chen, Shouyong Zhou, Haifeng Han, Mingliang Zhang, Hongdeng Qiu.  (2022)  A carbonylative coupling approach to alkyl stationary phases with variable embedded carbamate groups for high-performance liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,  1661  (462718).  [PMID:34875517] [10.1016/j.chroma.2021.462718]
7. Zhaoyan Zhao, Yuchen Xiao, Lingqing Xu, Ye Liu, Guanmin Jiang, Wei Wang, Bin Li, Tianchuan Zhu, Qingqin Tan, Lantian Tang, Haibo Zhou, Xi Huang, Hong Shan.  (2021)  Glycyrrhizic Acid Nanoparticles as Antiviral and Anti-inflammatory Agents for COVID-19 Treatment.  ACS Applied Materials & Interfaces,  13  (18): (20995–21006).  [PMID:33930273] [10.1021/acsami.1c02755]
8. Ting Pan, Yali Lin, Quanzhou Wu, Kaiwen Huang, Jianfeng He.  (2020)  Preparation of boronate-functionalized surface molecularly imprinted polymer microspheres with polydopamine coating for specific recognition and separation of glycoside template.  JOURNAL OF SEPARATION SCIENCE,  44  (12): (2465-2473).  [PMID:32367689] [10.1002/jssc.202000125]
9. Ting Tong, Hongwei Hu, Junwei Zhou, Shuangfei Deng, Xiaotong Zhang, Wantao Tang, Liurong Fang, Shaobo Xiao, Jiangong Liang.  (2020)  Glycyrrhizic-Acid-Based Carbon Dots with High Antiviral Activity by Multisite Inhibition Mechanisms.  Small,  16  (13): (1906206).  [PMID:32077621] [10.1002/smll.201906206]
10. Qiu Miao, Huang Keqing, Liu Yanzhuo, Yang Yuqing, Tang Honglin, Liu Xiaoxiao, Wang Chenlong, Chen Honglei, Xiong Yu, Zhang Jing, Yang Jing.  (2019)  Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis.  Mucosal Immunology,  12  (4): (945-957).  [PMID:30755716] [10.1038/s41385-019-0144-6]
11. Haixia Li, Dandan Guo, Liangran Zhang, Xiao Feng.  (2018)  Glycyrrhizin attenuates histamine-mediated MUC5AC upregulation, inflammatory cytokine production, and aquaporin 5 downregulation through suppressing the NF-κB pathway in human nasal epithelial cells.  CHEMICO-BIOLOGICAL INTERACTIONS,  285  (21).  [PMID:29452068] [10.1016/j.cbi.2018.02.010]
12. Zhen-Huan Lv, Trinh Anh Phuong, Shi-Jie Jin, Xiao-Xue Li, Ming Xu.  (2017)  Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes.  Oncotarget,  (53): ( 91291–91305).  [PMID:29207644] [10.18632/oncotarget.20443]
13. Huang Run-Yue, Chu Yong-Liang, Jiang Ze-Bo, Chen Xiu-Ming, Zhang Xian, Zeng Xing.  (2014)  Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase.  CELLULAR PHYSIOLOGY AND BIOCHEMISTRY,  33  (2): (375-388).  [PMID:24556579] [10.1159/000356677]

Solution Calculators