GN 44028 - ≥98%(HPLC), high purity , CAS No.1421448-26-1

  • ≥98%(HPLC)
Item Number
G288045
Grouped product items
SKUSizeAvailabilityPrice Qty
G288045-5mg
5mg
In stock
$276.90
G288045-10mg
10mg
In stock
$498.90
G288045-25mg
25mg
In stock
$1,121.90
G288045-50mg
50mg
In stock
$2,019.90
G288045-100mg
100mg
In stock
$3,634.90

Potent HIF-1α inhibitor

Basic Description

SynonymsN-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine;GN44028
Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads

Associated Targets(Human)

HIF1A Tchem Hypoxia-inducible factor 1-alpha (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EP300 Tchem Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
INCHI InChI=1S/C18H15N3O2/c1-2-4-13-11(3-1)9-14-17(13)20-21-18(14)19-12-5-6-15-16(10-12)23-8-7-22-15/h1-6,10H,7-9H2,(H2,19,20,21)
InChi Key CGZKSZVSWAAUHE-UHFFFAOYSA-N
Canonical SMILES C1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54
Isomeric SMILES C1COC2=C(O1)C=CC(=C2)NC3=NNC4=C3CC5=CC=CC=C54
PubChem CID 71625259
Molecular Weight 305.33

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
K2218453Certificate of AnalysisAug 29, 2022 G288045
K2218454Certificate of AnalysisAug 29, 2022 G288045
K2218455Certificate of AnalysisAug 29, 2022 G288045
K2218456Certificate of AnalysisAug 29, 2022 G288045
K2218469Certificate of AnalysisAug 29, 2022 G288045

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 30.53, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.53, Max Conc. mM: 100

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