Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G287416-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $97.90 | |
G287416-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $162.90 | |
G287416-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $325.90 | |
G287416-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $543.90 | |
G287416-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $979.90 |
Group II PAK inhibitor; potently inhibits PAK4 and PAK 6
Specifications & Purity | ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | Inhibitor of group II p21 activated kinases (PAK; IC50values are 7.5, 126 and 36 nM for PAK4, PAK5 and PAK6, respectively). Displays selectivity for group II PAK over a panel of 222 kinases. Inhibits tumor cell proliferation, migration and invasion in two |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol |
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INCHI | InChI=1S/C22H26N6O2/c1-30-14-13-25-21-26-17-6-5-16(7-11-22(29)9-3-2-4-10-22)15-18(17)28(21)19-8-12-24-20(23)27-19/h5-6,8,12,15,29H,2-4,9-10,13-14H2,1H3,(H,25,26)(H2,23,24,27) |
InChi Key | RZXMIHOUHYSGJO-UHFFFAOYSA-N |
Canonical SMILES | COCCNC1=NC2=C(N1C3=NC(=NC=C3)N)C=C(C=C2)C#CC4(CCCCC4)O |
Isomeric SMILES | COCCNC1=NC2=C(N1C3=NC(=NC=C3)N)C=C(C=C2)C#CC4(CCCCC4)O |
PubChem CID | 68181954 |
Molecular Weight | 406.48 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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L2404251 | Certificate of Analysis | Dec 07, 2024 | G287416 |
H2223264 | Certificate of Analysis | Jun 21, 2022 | G287416 |
H2223265 | Certificate of Analysis | Jun 21, 2022 | G287416 |
H2223403 | Certificate of Analysis | Jun 21, 2022 | G287416 |
H2223404 | Certificate of Analysis | Jun 21, 2022 | G287416 |
H2223405 | Certificate of Analysis | Jun 21, 2022 | G287416 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 40.65, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 40.65, Max Conc. mM: 100 |
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