Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G650461-2mg | 2mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $194.90 | |
G650461-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $420.90 | |
G650461-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $780.90 | |
G650461-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,400.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.\nIC50 value:\nTarget: GPR40\nPreparation of spiropiperidine derivatives for use as antidiabetic agents\nBy Hamdouchi, Chafiq; Lineswala, Jayana Pankaj; Maiti, Pranab \nFrom P |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.IC50 value:Target: GPR40Preparation of spiropiperidine derivatives for use as antidiabetic agentsBy Hamdouchi, Chafiq; Lineswala, Jayana Pankaj; Maiti, PranabFrom PCT Int. Appl. (2011), WO 2011066183 A1 20110603. Form:Solid |
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IUPAC Name | (3S)-3-[4-[[5-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acid |
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INCHI | InChI=1S/C31H31NO3S/c1-2-5-25(20-30(33)34)23-8-10-26(11-9-23)35-22-28-13-12-27(36-28)21-32-18-16-31(17-19-32)15-14-24-6-3-4-7-29(24)31/h3-4,6-15,25H,16-22H2,1H3,(H,33,34)/t25-/m0/s1 |
InChi Key | YSVQUSMRABAJAR-VWLOTQADSA-N |
Canonical SMILES | CC#CC(CC(=O)O)C1=CC=C(C=C1)OCC2=CC=C(S2)CN3CCC4(CC3)C=CC5=CC=CC=C45 |
Isomeric SMILES | CC#C[C@@H](CC(=O)O)C1=CC=C(C=C1)OCC2=CC=C(S2)CN3CCC4(CC3)C=CC5=CC=CC=C45 |
PubChem CID | 52936292 |
Molecular Weight | 497.65 |
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