GPR52 antagonist-1 - 98%, high purity , CAS No.1239987-91-7

Item Number

G648112

Grouped product items
SKU	Size	Availability	Price
G648112-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$70.90
G648112-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$110.90
G648112-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90
G648112-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$380.90
G648112-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$610.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC 50 of 0.63 μM. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC 50 of 0.63 μM. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons In Vivo GPR52 antagonist-1 (Compound 43) (5 mg/kg; i.p.; once a day for 4 weeks) reduces mHTT levels and rescues HD-related phenotypes in HdhQ140 mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC 50 : 0.63 μM (GPR52)

Names and Identifiers

IUPAC Name	(E)-5-phenyl-1-thiophen-2-ylpent-2-en-1-one
INCHI	InChI=1S/C15H14OS/c16-14(15-11-6-12-17-15)10-5-4-9-13-7-2-1-3-8-13/h1-3,5-8,10-12H,4,9H2/b10-5+
InChi Key	XUIAIACHIPOOHR-BJMVGYQFSA-N
Canonical SMILES	C1=CC=C(C=C1)CCC=CC(=O)C2=CC=CS2
Isomeric SMILES	C1=CC=C(C=C1)CC/C=C/C(=O)C2=CC=CS2
PubChem CID	156588927
Molecular Weight	242.34

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Basic Description