| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab106524-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $66.90 | |
| Ab106524-50μl | 50μl | In stock | $199.90 | |
| Ab106524-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $309.90 | |
| Ab106524-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $3,089.90 |
pAb; Rabbit anti Human Grp75 Antibody; WB, IHC; Unconjugated
| Product Name | Grp75 Antibody - Primary antibody, specific to Grp75, Rabbit IgG |
|---|---|
| Synonyms | 75 kDa glucose regulated protein antibody | 75 kDa glucose-regulated protein antibody | CSA antibody | Glucose Regulated Protein antibody | Grp 75 antibody | GRP-75 antibody | GRP75 antibody | GRP75_HUMAN antibody | Heat shock 70 kDa protein 9 antibody | |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, 0.6 mg/mL |
| Host species | Rabbit |
| Specificity | Grp75 |
| Immunogen | A synthetic peptide derived from human HSPA9 (AA 114-157). |
| Positive Control | WB: A549, MCF-7, HEK293, HeLa, Jurkat, NIH/3T3 and C6 cell lysates. IHC: Human brain tissue. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, Validated |
| Product Description | Rabbit anti Human Grp75 Antibody, Polyclonal antibody, could be used for WB, IHC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 Protein Function Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Grp75 Antibody (Ab106524) - Western Blot
All lanes: Grp75 Antibody (Ab106524) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 75 kDa
Observed band size: 74 kDa
Exposure time: 4.5 s
Grp75 Antibody (Ab106524) - IHC
Immunohistochemistry analysis of paraffin-embedded Human brain using Grp75 Antibody (Ab106524). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
| IHC | 1/50 - 1/100 "> 1/50 - 1/100 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1202094 | Certificate of Analysis | Dec 19, 2023 | Ab106524 |
| ZJ23F1202095 | Certificate of Analysis | Dec 19, 2023 | Ab106524 |
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| 2. Hochstrasser, D F DF and 9 more authors.. (1992) Human liver protein map: a reference database established by microsequencing and gel comparison.. Electrophoresis, [PMID:1286669] |
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| 9. Uhrigshardt, Helge H, Singh, Anamika A, Kovtunovych, Gennadiy G, Ghosh, Manik M and Rouault, Tracey A TA.. (2010) Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis.. Human molecular genetics, (1): [PMID:20668094] |
| 10. Chen, Tim H-P TH and 6 more authors.. (2011) Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice.. Blood, (3): [PMID:21123823] |
| 11. Peng, Chao C and 18 more authors.. (2011) The first identification of lysine malonylation substrates and its regulatory enzyme.. Molecular & cellular proteomics : MCP, [PMID:21908771] |
| 12. Ahmad, Yasmeen; Boisvert, Francois-Michel; Lundberg, Emma; Uhlen, Mathias and Lamond, Angus I.. (2012) Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.. Molecular & cellular proteomics : MCP, [PMID:22002106] |
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| 16. Matsuzaki, Hiroshi H, Fujimoto, Takahiro T, Tanaka, Masatoshi M and Shirasawa, Senji S.. (2013) Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux.. Biochemical and biophysical research communications, (12): [PMID:23501103] |
| 17. Tsuneki, Masayuki M and 9 more authors.. (2013) Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells.. Biochemical and biophysical research communications, (26): [PMID:23541579] |
| 18. Cai, Kai K and 5 more authors.. (2013) Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).. The Journal of biological chemistry, (4): [PMID:23940031] |
| 19. Guo, Ailan and 15 more authors.. (2014) Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.. Molecular & cellular proteomics : MCP, [PMID:24129315] |
| 20. Schmitz-Abe, Klaus K and 27 more authors.. (2015) Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.. Blood, (17): [PMID:26491070] |
| 21. Royer-Bertrand, Beryl B and 14 more authors.. (2015) Mutations in the heat-shock protein A9 (HSPA9) gene cause the EVEN-PLUS syndrome of congenital malformations and skeletal dysplasia.. Scientific reports, (24): [PMID:26598328] |
| 22. Shan, Yuxi Y and Cortopassi, Gino G.. (2016) Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.. Mitochondrion, [PMID:26702583] |
| 23. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |
