GSDMB Antibody - Primary antibody, specific to GSDMB, Rabbit IgG

Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human GSDMB Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab106583
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab106583-10μl
10μl
In stock
$69.90
Ab106583-50μl
50μl
In stock
$199.90
Ab106583-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab106583-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,899.90

pAb; Rabbit anti Human GSDMB Antibody; WB; Unconjugated

Basic Description

Product NameGSDMB Antibody - Primary antibody, specific to GSDMB, Rabbit IgG
SynonymsGSDMB-1 | GSDML | PP4052 | PRO2521 | 123 antibody | 156 antibody | Gasdermin B antibody | Gasdermin like protein antibody | Gasdermin-B antibody | Gasdermin-like protein antibody | GSDMB antibody | GSDMB_HUMAN antibody | GSDML antibody | PP4052 antibody |
Specifications & PurityExactAb™, Validated, Carrier Free, 0.5 mg/mL
Host speciesRabbit
SpecificityGSDMB
ImmunogenRecombinant GSDMB expressed in E.coli (AA 208-237).
Positive ControlWB: A431 and MDA-MB-231 cell lysates.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human GSDMB Antibody, Polyclonal, could be used for WB and so on.
Application
WB: 1/1000
Protein Function
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified + Peptide affinity purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

GSDMB Antibody (Ab106583) - Western Blot
All lanes: GSDMB Antibody (Ab106583) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution

Predicted band size: 47 kDa
Observed band size: 41, 43, 45 kDa
Exposure time: 10.6 s

Associated Targets(Human)

GSDMB Tbio Gasdermin-B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303300Certificate of AnalysisMar 15, 2024 Ab106583
ZJ24F0303299Certificate of AnalysisMar 15, 2024 Ab106583

Related Documents

References

1. Yu, Y Y and 16 more authors..  (2001)  Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs..  Genome research,      [PMID:11483580]
2. Wan, Dafang D and 24 more authors..  (2004)  Large-scale cDNA transfection screening for genes related to cancer development and progression..  Proceedings of the National Academy of Sciences of the United States of America,    (2):   [PMID:15498874]
3. Zody, Michael C MC and 73 more authors..  (2006)  DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage..  Nature,    (20):   [PMID:16625196]
4. Sin, H-S HS and 9 more authors..  (2006)  Transcriptional control of the HERV-H LTR element of the GSDML gene in human tissues and cancer cells..  Archives of virology,      [PMID:16625320]
5. Sjöblom, Tobias T and 28 more authors..  (2006)  The consensus coding sequences of human breast and colorectal cancers..  Science (New York, N.Y.),    (13):   [PMID:16959974]
6. Tamura, Masaru M and 8 more authors..  (2007)  Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner..  Genomics,      [PMID:17350798]
7. Nguyen, Su Tien ST and 7 more authors..  (2007)  Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma..  Cancer science,      [PMID:17391312]
8. Bechtel, Stephanie S and 18 more authors..  (2007)  The full-ORF clone resource of the German cDNA Consortium..  BMC genomics,    (31):   [PMID:17974005]
9. Carl-McGrath, Stacy S, Schneider-Stock, Regine R, Ebert, Matthias M and Röcken, Christoph C..  (2008)  Differential expression and localisation of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic, and colon tissues..  Pathology,      [PMID:18038310]
10. Saeki, Norihisa N and 10 more authors..  (2009)  Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium..  Genes, chromosomes & cancer,      [PMID:19051310]
11. Chao, Kinlin L KL, Kulakova, Liudmila L and Herzberg, Osnat O..  (2017)  Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein..  Proceedings of the National Academy of Sciences of the United States of America,    (14):   [PMID:28154144]

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